Pulmonology Flashcards
Albuterol (Class & Use)
Beta 2
Short relief
Salmeterol (Class & Use)
Beta 2
Long relief
Formoterol (Class & Use)
Beta 2
Long relief
Beclomethasone (Class & Use)
Corticosteroid
Asthma
Budesonide (Class & Use)
Corticosteroid
Asthma
Fluticasone (Class & Use)
corticosteroid
Asthma
Ciclesonide (Class & Use)
Corticosteroid
Asthma
Zileuton (Class & Use)
5-LO inhibitor
Asthma
Zafirlukast (Class & Use)
LT Antagonist
Asthma
Montelukast (Class & Use)
LT Antagonist
Asthma
Cromolyn (Class & Use)
Mast Cell Inhibitor
Asthma
Omalizumab (Class & Use)
Anti-IgE monoclonal
Asthm
Ipratropium (Class & Use)
Muscarinic antagonist
COPD Relief
Codeine (Class & Use)
Opiate
cough
Dextromethorphan (Class & Use)
non opiate
Cough
Guaifenesin (Class & Use)
?
Expectorant
N-acetylcysteine (Class & Use)
mucolytic
COPD
Bosentan (Class & Use)
Endothelin antagonist
PAHtn
Sildenafil (Class & Use)
PDE5 inhibitor
PAHtn
Roflumilast (Class & Use)
PDE4 inhibitor
COPD relief
Albuterol (Side E.)
/HR,BS
\Mg,K
Most effective long term treatment of asthma symptom control
Corticosteroids
One of the only Prodrug asthma symptom controllers
ciclesonide (steroid)
Corticosteroids (adverse effects)
Thrush
dysphonia
\bone density
glaucoma
fast or slow inhale?
MDI's = Slow and deep DPI's = Quick and deep
LO & LT drugs (MOA & Admin)
pills (montelukast chewable)
inhibit mucus, constriction, eosinophils, and exudation.
Z’s /warfarin levels and liver enzymes
lung Anti-inflammatory (mastcells=histamine)
cromolyn
Omalizumab (MOA)
blocks IgE binding to mast cells
Best class of drugs for COPD
Muscarinic cholinergic antagonists
Then beta 2 & corticosteroid.
Causes of PAH
More ET-1 production over takes the effects of NO dilation and HTN takes over with constriction
Bosentan (side effect)
/ Liver enzymes