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Pharm > Pulmonary Meds > Flashcards

Pulmonary Meds Flashcards

1
Q

What are bronchioles composed of?

A

Smooth muscle and Elastic fibers

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2
Q

Parasympathetic innervation via the vagus nerves maintains what in the bronchioles?

A

Slight Constriction

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3
Q

The bronchioles are innervated by what?

A

Parasympathetic and Sympathetic nervous systems

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4
Q

What do anticholinergics do to smooth muscle?

A

They inhibit the action of Ach on smooth muscle, which reduces bronchospasm

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5
Q

What does an increased level of cyclic AMP result in?

A

Relaxation of smooth muscle

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6
Q

What 3 things to Beta 2 agonists do when they stimulate the sympathetic nerve receptors in bronchial smooth muscle?

A

Reduce Bronchospasm
Decrease glandular secretion
Increase vasoconstriction (to decrease edema)

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7
Q

What do PDE inhibitors do to promote bronchodilation?

A

They decrease the rate of cAMP degradation

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8
Q

Exercise induced asthma is best medicated with what drug?

A

Albuterol

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9
Q

What is the combo inhaled glucocorticoid and LABA that is used for bronchodilation and long term control of asthma?

A

Advair - Fluticasone and Salmeterol

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10
Q

What is the combo inhaled anticholinergic and SABA that is used for COPD patients who need 2 bronchodilators?

A

Combivent - Ipratropium and Albuterol

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11
Q

What is the combo inhaled long term anticholinergic and LABA that is used for patients for patients with COPD ?

A

Anoro Ellipta - Umeclidinium and Vilanterol

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12
Q

What is the combo inhaled corticosteroid and LABA used for patients who need maintenance of bronchodilation in asthma and COPD ?

A

Symbicort - Budesomide and Formoterol

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13
Q

What are the inhaled glucocorticoid?

A

Fluticasone

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14
Q

What is the MOA of fluticasone?

A

Decrease smooth muscle irritability; anti-inflammatory and anti-proliferative

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15
Q

What are the indications of fluticasone

A

Asthma (primarily)

COPD

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16
Q

What are some contraindications of fluticasone that should be considered?

A

Latent TB
Glaucoma
Cataracts

17
Q

What is the oral corticosteroid?

A

Prednisone

18
Q

What are the contraindications of Prednisone

A

TB
Glaucoma
Cataracts

19
Q

What is the mast cell stabilizer?

A

Cromolyn

20
Q

How does cromolyn work?

A

It decreases smooth muscle irritability, stabilizes mast cell membrane to prevent degranulation and release of leukotrienes

Pharm (12 decks)

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