Pulmonary equations Flashcards

1
Q

What is Laplace’s law?

A

Pressure = 2 X Surface tension/radius

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2
Q

What is the equation for lung compliance?

A

Change in lung volume/change in transpulmonary pressure

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3
Q

What is the equation for chest wall compliance?

A

Change in chest volume/change in transthoracic pressure

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4
Q

What is the equation for total compliance?

A

1/total compliance = 1/CW+1/CL

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5
Q

What is normal CW and CL?

A

200 ml/cm H2O

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6
Q

What is normal total compliance?

A

100 ml/cm H2O

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7
Q

What is the equation for oxygen content?

A

CaCO2 = (1.34 X Hb X SaO2) + (0.003X PaO2)

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8
Q

What is a normal oxygen content?

A

16-22

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9
Q

What is the equation for ventilation?

A

PaCO2 = VCO2/VE-VD

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10
Q

What is the equation for VE?

A

Tidal volume X RR

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11
Q

What is VE?

A

total minute ventilation

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12
Q

What is VD?

A

Dead space ventilation

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13
Q

What is the equation for alveolar ventilation?

A

VA = (VT-VD) X RR

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14
Q

What is the the equation for physiologic dead space?

A

VD = anatomic dead space + alveolar dead space

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15
Q

What is the normal dead space to tidal volume fraction?

A

0.3 = VD/VT

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16
Q

What is the equation for mixed venous saturation (SvO2)?

A

VO2/CO X Hb X 13

17
Q

What is normal SvO2?

A

65-75%

18
Q

What is normal PvO2?

A

35-45 mmHg

19
Q

What is normal P50?

A

27 mmHg

20
Q

What is P50?

A

the partial pressure of oxygen at which hemoglobin is 50% saturated

21
Q

What is the normal V/Q ratio?

A

1

22
Q

What does it mean if V/Q = infinity?

A

There is a perfusion problem - lots of dead space

23
Q

What does it mean if V/Q is below 1

A

There is a ventilation problem (Interstitial lung disease)

24
Q

What is an absolute shunt?

A

When there is perfusion, but no ventilation. V/Q = 0

25
Q

What is the equation for a shunt fraction?

A

QS/QT = CcO2-CaO2/CcO2 - CVO2

26
Q

What is a normal QS/QT?

A

0.1

27
Q

What is the equation for partial pressure of oxygen in the alveoli?

A

PAO2 = (PB - PH2O) X FiO2 - (PaCO2/0.8)

28
Q

What is the equation for the A/a gradient?

A

PAO2-PaO2

29
Q

What is a normal A/a gradient?

A

10-20 mmHg

30
Q

What is the equation for normal PaO2 associated with age?

A

102-age/3

31
Q

What is the equation for normal PaO2 using FiO2?

A

5 X FiO2