Pulmonary Embolism/DVT Flashcards
What is a pulmonary embolus ?
Thrombus (clot) that lodges in a segment of the pulmonary arterial system
What does a pulmonary embolus cause and what occurs in the body as a result?
Full/partial obstruction of pulmonary blood flow - causes a decrease in oxygenation
What are some of the risk factors associated with VTE (venous thromboembolism)
Age
Immobilisation
Surgery esp ortho surgery
Obesity
Pregnancy and post-partum
Acute CVA
Chronic lung disease
Post surgery/trauma
IV therapy, CV catheters
Hypercoagulability
Smoking
What is DVT (deep vein thrombosis)
Acute venous insufficiency caused by clot deep in venous system
What are some of the S and S associated with DVT
Oedema, pain , erythema + warmth, peripheral distension
When does a DVT become a pulmonary embolism
When the clot breaks off within the vein, enters circulation and ends up in the lungs
Varichow’s Triad include the 3 main categories that can cause blood clot formation. It also helps us identify those who are at risk of forming these clots. Name these categories.
Stasis of Venous circulation
Hypercoagulability
Endothelial damage (anything that causes damage to vein vessel)
What are some of the things that can cause stasis of venous circulation?
Immobilisation
Varicose veins
Surgery
Travelling for a long time w/o moving
Heart failure, A-fib
Obstruction - late pregnancy, obesity
What are some of the things that increases blood coagulation ?
Cancer
Severe illness- sepsis
Dehydration
Usage of oestrogen ( birth control)
Heparin induced thrombocytopenia (HIT)
Post partum
What are some of the things that can cause endothelial damage ?
IV therapy - venipuncture
Central line cath, heart valve - in dwelling devices
Meds
Trauma/ injury to vessel eg. Surgery
What are some of the S+S of PE
Tachypnoea- RR > 20 bpm
Hypotension
Signs of DVT- red, swollen calf
Pleural rub- squeezing/grating sound caused by ischemic lung tissues coming in contact with pleura
Cyanosis
SOB
Cough
Tachycardia- >100bpm
Pleuritic chest pain
Coughing up blood (haemoptysis)
Dizziness/fainting
What are some of the tests done for PE/DVT
Pt hx and phys exam
US (DVT)
Chest x-ray w contrast dye
ECG
ABG
D- dimer test
MRI
ECHO
CT pulmonary angiography
Familial/genetic testing
What does a d-dimer test assess for ?
Assess blood for fibrin degradation fragment
What is a fibrin degradation fragment ?
Protein fragment that hangs out in blood when clot has presented and started to break down
What does a d-dimer test do and not do ?
Can diagnose blood clots
Does not tell location of clot
Sometimes gives false positive result