Pulmonary Disease Flashcards
Chronic inflammatory airway disorder
•Airway hyper-responsiveness to stimuli
•Bronchial edema
•Narrowing of the airways i.e., obstruction
Asthma
Signs and Symptoms of \_\_\_\_\_: Recurrent, reversible episodes of: •Dyspnea (shortness of breath) •Wheezing •Coughing •Tightness of chest
Asthma
Which of the following is a “true” asthma symptom? •Dyspnea (shortness of breath) •Wheezing •Coughing •Tightness of chest
•Tightness of chest
What stage of asthma should not be treated for routine dental care?
Uncontrolled
____ type of asthma
•Most common
•Children and young adults
•Typical positive family history
•Triggered by allergens (pollen, dust, house
mites, animal dander, mold etc.)
•Exaggerated inflammatory response Allergen →T Helper Lymphocyte Type 2 (Th2) →antibody production of high levels of IgE →activation of mast
cells, basophils and eosinophils → bradykinin, histamine, leukotrienes → bronchoconstriction
- Extrinsic (allergic or atopic)
____ type of asthma
•Unknown pathogenesis
•Children and young adults
•Triggered by exercise and thermal changes
•Cold air irritates mucosa resulting in airway
hyperactivity
- Exercise-induced
____ type of asthma
•Second most common
•Middle-aged individuals
•Triggered by respiratory irritants (tobacco, air
pollution, emotional stress, gastroesophageal reflux
disease (GERD)
•Infrequently associated with family history
•Normal IgE levels
Intrinsic (idiosyncratic, nonallergic, nonatopic)
____ type of asthma
•Subset of intrinsic
•Affects children, young adults & middle-aged adults
•Common antigens
➢NSAIDs, ASA (acetyl salicylic acid)
➢β-blockers
➢ACE (angiotensin-converting enzyme) inhibitors
➢Anticholinergic drugs (?)
➢Food dye
➢Metabisulfites in food and in local anesthetics with
epinephrine
- Drug-induced
Oral signs of \_\_\_\_\_: •Mouth breather (high palatal vault, overjet, crossbite, greater facial height) •Dry mouth •Candida •Enamel defects and caries •Gingivitis/periodontitis •Enamel erosion possible with GERD
Asthma
_______ Asthma
• Dental treatment should be limited to urgent care
only
• Treatment of acute pain, bleeding, or infection
Unstable
______ Asthma
• Any indicated dental treatment may be provided if
management protocols are considered
• Consult with physician for severe persistent
asthma
Stable
What 2 drugs are mentioned that trigger asthma?
ASA and NSAIDs
What 2 drugs are mentioned that cause respiratory depression causing issues with asthma?
Opioids and barbituates
_______ in epinephrine preparation of local anesthetics should be avoided in asthmatic pts
Sulfites
________
➢Potent inhibition of CYP3A4
➢Increases levels of theophylline
➢Toxicity (arrhythmia and seizures)
Theophylline and macrolides or ciprofloxacin