Pulmonary/Chest Cases Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Asthma in the ED

A
  • Bilateral wheezing is the hallmark
  • Dyspnea, cough, chest “tightness”
  • Pronged expiratory phase, I:E ratio 1:3 or 4
  • Tachypnea, tachycardia, hypoxia, hypercarbia
  • Poor peak expiratory flow measurements (PEFR)
  • Med non-compliance, viral illness most common reasons
  • “All that wheezes isn’t asthma”
  • New onset after 40yo is likely NOT asthma
  • Correct the exacerbation: that is the goal

-You dont develop primary asthma after age 40

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2
Q

Mild to moderate asthma exacerbations

A
  • Hand held nebulizer – asap Albuterol 2.5mg in nebulizer:
    • Once, x3 q20min or 10ml/1 hr
  • Oral Prednisone (60mg) PO (as good as IV initially)
  • Peak flow (PEFR) after each neb tx, repeat VS, reassess
  • Usually no need for labs, CXR, EKG, ABG, etc…unless…
    • Severe sx’s, fever, not improving, get worse or considering alternate Dx

-Albuterol nebulizer dosing: 2.5mg Albuterol (0.5ml of 0.5% diluted in 3ml normal saline)
-If shes a smoker or has COPD, you would consider Atrovent as well
-PREDNISONE IS KEY
-The HR will increase after the neb treatment – if the HR is now 160, THAT’S A PROBLEM
USUALLY NO NEED FOR LABS, CXR, ETC!!!
-If they have a fever, you need CXR

  • Walk ‘em – while youre walking, you want to hear them speak. If they cant say a sentence without taking a breath, they cant go home!
  • Most people do 60mg oral steroid
  • B2 agonists can cause the lactic acid to rise
  • If someone with asthma has ever been intubated,, that should scare you
  • If they’ve ever had an exacerbation with a steroid burst, THEY CANNOT GO HOME!!
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3
Q

When to discharge asthma exacerbations

A
  • Walk ‘em, assure f/u, return precautions
  • Rx’s: Oral steroid burst (60mg x5d or tapered dose Rx), inhaled steroid prescription
  • Can’t go home if…
    • Not responding to treatment, worsening
    • Hypoxic - ambulatory pulse ox <94-95%
    • PEFR not improved to 65-70% predicted
    • ED visit in past 3 days for same
    • Exacerbation during steroid burst
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4
Q

COPD in the ED

A
  • Exacerbations common, but why?
    • Disease progression
    • Med non-compliance, out of home O2
    • Infection - viral, bronchitis, pneumonia
    • Cardiac - pump failure/impairment, arrhythmia
    • Metabolic acidosis, other illness on top
    • Exposure/environment
    • Sedation, drugs
  • Treatment goals – reverse hypoxia, reverse hypercarbia, restore effective ventilation
  • Is this COPD or something else??

On CXR:
-Hyperexpanded lung fields, narrow
cardiac silhouette, flat diaphragms,
blunted costophrenic angles

  • New arrhythmia with COPD exacerbation is NOT GOOD!!
  • MUDPILERS – metabolic acidosis
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5
Q

COPD diagnosis and tx

A
  • IV, monitor, CXR, EKG, lung/cardiac US, labs (cbc, cmp, Utox, +/- troponin)
  • Continuous nebulizer treatments
    • Beta 2 agonists (10mg over 1h)
    • Inhaled anticholinergics
  • Oral steroids, IV if admit
  • Antibiotics if appropriate
  • NIPPV: Bipap – Bi-level positive airway pressure
    • If no response to above tx
  • Albuterol + Atrovent (Ipratropium) = DuoNeb– > 3mg Albuterol/0.5mg Ipratropium
  • COPDers are often much older and sicker than asthmatics – don’t turn around as quickly as asthmatics
  • IV O2 monitor
  • Lung and cardiac US very important
  • Beta 2 agonists, anticholinergics and steroids!
  • Most of the time, people use doxy because these people often get weird pneumonias

-COPDers that fall asleep with RR of 40, THEY ARE HYPERCARBIC!!

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6
Q

When should you NOT send home a COPD exacerbation

A
  • Not responding, worsening symptoms/signs
  • Mental status changes
  • If require Bipap (usually)
  • Hx recent severe exacerbations/intubation
  • Older, co-morbidities
  • New arrhythmia
  • Uncertain of diagnosis
  • Poor ambulatory pulse ox
  • Poor home support
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7
Q

pneumothorax

A

-IV, O2, monitor; EKG, tx pain

  • CXR – search edges
    • +/-Expir film, lateral decub; deep sulcus sign if in bed
  • Bedside ultrasound
    • Absence of “comet tailing”; the friction of pleural sliding
  • Shock? Or stable now?
    • Can deteriorate quickly
  • Primary or Secondary?
  • Chest CT
  • Surgery consult
  • Tall young males who have spontaneous pneumothorax
  • What made you think this? He had a sudden onset, decreased pulse ox, increased RR
  • Not thinking PNA or MI because hes 19
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8
Q

Treatment of pneumothorax

A
  • Treatment depends on size
    • Pigtail catheter w/ Heimlich valve
    • Chest tube

-Majority are admitted to Surgery

  • Small, primary pneumos (<15% total lung) in select cases, a stable patient can go home if:
    • Not a secondary pneumo
    • Stable vitals after 3-4hrs
    • Repeat CXR with no enlargement
    • Pt is reliably able to return in 12-24hrs for repeat CXR
    • If catheter re-expansion (Stable x6hrs)
    • Surgical consult agrees
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9
Q

Tension pneumothorax

A
  • Air into pleural space - one-way valve
  • Rare, deadly: seconds count
  • Clinical diagnosis - often post-trauma
    • Severe dyspnea, sudden change in VS/LOC
    • *Decreased breath sounds affected side
    • *Hypotension
    • *Distended neck veins
    • *Tracheal shift
  • Needle thoracentesis: 2nd ICS at MCL
  • Follow with chest tube immediately
  • This is a CLINICAL diagnosis!! NOT AN XRAY DIAGNOSIS
  • This person will die if you don’t treat it!!
  • Usually a 16 gauge that you can find – 2nd intercostal space at the mid clavicular line
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10
Q

Pulmonary effusion

A
  • IV, O2, monitor, pain control, labs
  • CXR; Lateral decubitus film – does it layer out?
  • Bedside ultrasound - see fluid, guides tap – also check for pericardial effusion
  • Chest CT - gold standard
    • Excellent for small effusions, other dx’s
    • CT guided thoracentesis if loculated – doesn’t layer out
  • Effusions can be infectious, malignant, reactive, chronic, post-surgical, traumatic
  • If you get a pleural effusion, you as the practitioner need to check for pericardial effusion!!
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11
Q

pulmonary effusion treatment

A
  • Sick? Is this shock? Fever?
  • Triple scan US: fluid status, pericardial effusion
  • US guided Thoracentesis
    • Diagnostic and therapeutic
    • Slow removal of fluid - ultrasound guided
    • No more than 1000 - 1500ml (To avoid re-expansion pulmonary edema)
    • CXR after to check for pneumothorax

-Pleural fluid analysis

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12
Q

The flu red flags

A
  • Who should you be worried about?
    • Young, old, immunocomp, recent surg/hosp, lung Dz

-Who gets a CXR

  • Hypotension/tachy/tachy/fever, hypoxic, lung findings
    • **No viral syndrome sx’s, worsening, sx’s >2wks
  • Who gets moved to the main ED?
    • Abnormal VS, chest pain, young/old, risks, look sick
  • Which Hx/PE findings really make a difference?
    • ROS: SOB, DOE, hemoptysis, leg edema/pain, syncope
    • PMHx (cardiac, lung dz, DM, steroids), SH (etoh, home)
    • VS, diaphoresis, new wheezes, rales, edema, rash

-Who has the flu vs. who has pneumonia, other dx??

  • Tachy tachy = tachycardic and tachypnic
  • Bacteria, PNA are different – cough (sore throat), no n/v, no diarrhea
  • If you don’t have viral sxs (runny nose, upset stomache, n/v, diarrhea, etc.)
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13
Q

pneumonia

A
  • Common: sick or not sick? Know Sx’s/Red Flags/Risks
  • CXR for Dx
  • If +/- sick, risks: lactic acid for sepsis; labs, CURB65
  • Admit sick; D/C not sick w/ close f/u, return precautions
  • Abx: Azithro, Levo?, Doxy
  • If D/C: educate, sx relief
  • 100 CXR’s…
  • CURB65 – clinical decision score to determine 30 day mortality risk in patients with pneumonia.
  • Points for confusion, BUN, respiratory rate, blood pressure, age >65
  • Higher the score, greater risk for 30 day mortality. Indication for admission
  • PNA is a big cause of sepsis so you need to recognize it!
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14
Q

Hemoptysis

A
  • Pulmonary or non-pulmonary?
  • Amount in 24hrs? Small amounts common
  • Hemodynamically stable?
  • Common causes:
    • Pneumonia
    • Coumadin/thinners
    • Tuberculosis
    • Cancer
    • Pulmonary embolus
    • Hematemesis?
    • Nasal, dental, oral source?
    • Trauma
  • ABC’s, vitals; IV(s), O2, monitor
  • Hx: Onset? Chest pain? SOB? Weight loss? Fever? Trauma? Coumadin/thinners? CAM?
  • PE: Usual suspects + look for non-pulmonary source
  • CXR, EKG, Labs, lactic acid, PT/INR. Type and screen/cross?
  • Chest CT if significant
  • If very significant, ongoing: a big airway concern. Make a plan
  • Pulmonary consult: bronchoscopy
  • Admit: significant or bad dx
  • Hemodynamically stable = appropriate BP and nomal HR
  • If hemoptysis is significant, you need a chest CT to find out why
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15
Q

HIV with infitrates

A
  • IV, O2, monitor
  • CXR, labs, lactic acid, LDH, cultures, HIV labs: CD4 count, viral load
    • CD4 >200 = immunocompetent
  • Need isolation? Reverse Isolation? TB concern? Mask
  • Tx common and special pathogens
    • Rapid initiation of IV Abx
  • Monitor LOC, respiratory effort
  • Admit all immunocompromised pt’s if febrile and/or hypoxic
  • LDH is very important for AIDS pts
  • Note their respiratory effort
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16
Q

Tuberculosis clinical presentation

A
  • Classic: Cough, fever, weight loss, fatigue, night sweats, pleuritic chest pain, dyspnea and hemoptysis.
  • High index of suspicion
    • Classic sx’s, endemic area of origin - travel
    • Risks: immunocomp, incarcerated, known exposure, homeless, EtOH
  • Lung exam variable
  • Hx +PPD – reactivation TB
  • Multi-drug resistance
  • If respiratory distress - are very sick
17
Q

Tuberculosis ED diagnostics

A
  • Mask, isolation precautions asap
  • Chest Xray asap
    • Infiltrates/consolidation
    • Reactivation favors upper lobes
    • Pleural effusion
    • Cavitary lesions
    • Calcifications
    • Miliary pattern
  • PPD?
  • Sputum for AFB, culture
  • Quantiferon Gold - an aid for detecting latent Mycobacterium tuberculosis infection. It measures a component of cell-mediated immune reactivity to M. tuberculosis. The test is based on the quantification of interferon-gamma (IFN-) released from sensitized lymphocytes in whole blood incubated overnight with purified protein derivative (PPD) from M. tuberculosis and control antigens.
  • Result is not affected by prior BCG
18
Q

TB disposition in the ED

A
  • Suspected TB in respiratory distress = admit
  • High risk, classic symptoms, CXR with any infiltrate or effusion = you are done – admit
  • Positive PPD hx, CXR neg, classic symptoms = admit
  • Unknown PPD + risk + sx’s + neg CXR = place PPD, get Quantiferon Gold, admit if sick, close f/u if not sick
  • Positive PPD, CXR neg, no sx’s = home, PCP or TB coordinator f/u to initiate treatment
  • ED rarely initiates outpatient treatment
  • Outpatient TB treatment is complicated. Must identify appropriate drug, requires monitoring (compliance and LFT’s). ED not suited for this level of follow-up.
  • Classic sxs: cough, night sweats, weight loss, hemoptysis
19
Q

Differential Diagnosis for Breathlessness, chest tightness, pale, anxious, uncomfortable

A
  • CHF
  • AMI/ACS
  • PE
  • Pericardial effusion
  • Infection
  • Pleural effusion
  • Renal failure
  • Cancer
  • Begin with: IV, O2, monitor, EKG, CXR, Triple scan ULS (then formal)
  • CBC, CMP, lactic acid, troponin, UA, Tox screen
  • Solid Hx & PE when more stable
  • **BNP: $$, positive in PE/COPD too.
  • Order when Dx unclear, no ULS available
20
Q

Cardiogenic pulmonary edema

A

-CHF is a simplified term for a more complex problem
-Structural or functional inability of ventricles to fill and pump blood effectively:
-Acute (less common, emergent) vs. Chronic (common, familiar, recurrent)
Acute: ”flash” pulmonary edema; L-sided – MI, HTN emergency, valve rupture, etc
-Chronic: HTN, valve Dz, CAD -> cardiomegaly, mitral regurg, aortic stenosis, etc

-Think: Left or Right-sided (or both) failure? Systolic or Diastolic failure?
-Low or High output failure?
Left sided: left ventricle fails to pump blood out effectively (Sx’s: DOE, cough, fatigue, orthopnea, PND, rales, S3 gallop.)
-Right sided: usually result of left sided failure (Sx’s: JVD, peripheral edema, hepatomegaly, anasarca)
-Systolic: ventricle can’t “squeeze” enough to empty contents. Low EF, common
-Diastolic: “Squeeze” ok but ventricle can’t “relax” to fill during diastole
-Low output: common, chronic CHF. Low EF
-High output: compensating for demand: thyroid storm, anemia, etc

  • Symptoms mimic several entities – keep a broad DDx!!
  • Flash pulmonary edema – result of sudden rise in left-sided filling pressures
21
Q

CHF tx

A
  • Reduce preload, afterload with Vasodilators -> Nitroglycerin
  • IV (100mics), sublingual (0.4mg = 400mics!) waiting for drip
  • **No NTG if RV/inferior MI, Viagra, tamponade, aortic stenosis, hypovolemia
  • Diuretics IF volume overload: Lasix is first choice (US the IVC)
  • NIPPV is first line tx, if sick
  • Oxygen, Positioning
  • Admit all new CHF – search for cause – this is key!
  • Admit moderate, severe, recurrent or unstable CHF

BNP is expensive (>$200 in our ED)

  • Nitro contraindicated if RV infarct/inferior wall MI, Viagra, aortic stenosis, pericardial tamponade. May start lower than 100mics – often tx with 200mics or more
  • Morphine is weak vasodilator and sometimes indicated/helpful

-Isolated diastolic dysfunction is not common and is complex and difficult to manage. Consult the intensivist/ICU team for recommendations

22
Q

Symptomatic Anemia

A
  • Anemia is often chronic, well compensated:
  • Increase cardiac output (HR) for O2 delivery to tissues when needed.
  • When compensation fails = Sx’s: DOE, dizzy, weak, malaise, palpitations, chest pain, syncope
  • Transfusion is treatment
    • Not benign! It’s not the numbers. It’s the sx’s, effects of low Hgb
    • Risks: transfusion Rx, infection, hyperkalemia
  • Type/screen, type/cross for packed red blood cells (units)
  • So…why is this patient anemic?? Melena? Menstrual? Cancer? Renal Failure? Iron? Macro- or Microcytic?
23
Q

Thoracic Aortic Dissection

A
  • Marfan’s, Ehlers-Danlos, connective tissue dz, pregnancy, syphilis, family hx of sudden death at young age – all are risk factors
  • Classic: sudden “tearing/ripping” w/ SOB, HTN. Jaw, neck, chest - pain evolves, changes. Rarely classic presentation….
  • Migrating pain above and below the diaphragm; GI complaints – n/v/d
  • Dizziness, near-syncope, neuro sx’s common
  • If sx’s present, consider this Dx – it is elusive
    • Document risk factors - you thought of it
  • CT chest w/ contrast, Transesophageal echo
  • Young patients with SOB, chest discomfort can be sick too!
  • Ehlers-Danlos syndrome: inherited connective tissue disease, 13 subtypes, incurable. Features: hypermobile joints; stretchy, “velvety”, fragile skin that bruises easily; vascular fragility/rupture
  • Syphilis can cause this!!!
  • Ripping in my chest -> SCAN IMMEDIATELY!!
  • Radiation to the back -> think aorta!!
24
Q

Venous thromboembolism

A
  • Deep Venous Thrombosis (DVT) & Pulmonary embolus (PE)
    • DVT: Unilateral leg pain, edema, warmth (leg most common)
    • PE: Clot has travelled to the pulmonary vasculature
  • Risk: Virchow’s Triad (1856)
    • Venous Stasis: LE cast, hospital stay, bedridden, travel, paralysis
    • Hypercoagulability: previous DVT/PE (#1 risk), malignancy, increased estrogen, coagulation dz, inflammatory (Pregnancy; hormone BC; Factor V Leiden, Protein S, C or antithrombin III deficient, lupus, sickle cell, vasculitis)
    • Endothelial damage: recent surgery (<3mos), trauma, indwelling venous catheter, IVDU
  • PE is a complication of DVT
  • Risk factors for DVT same as for PE
  • ER is the one that diagnoses this!
  • Rare to have primary clot ONLY in your chest
  • NUMBER ONE RISK IS PREVIOUS DVT OR PE
25
Q

Pulmonary embolism

A
  • 650,000 diagnosed in US/year; 400,000 missed dx; 30% dx’d at autopsy
  • 3rd leading cause death in hospitalized pt’s
  • Ventilation-perfusion mismatch: no perfusion = no diffusion
  • Right heart outflow impeded -> reduction in left ventricular preload -> refractory hypotension -> shock -> death
  • Massive PE: dramatic presentation
  • Submassive/segmental PE: everyone else – this is our challenge
26
Q

When do you suspect a PE

A
  • Consider PE in everyone w/ chest pain or…classic presentation:
    • Sudden/rapid, unexplained dyspnea
    • Pleuritic chest pain, resting tachycardia
    • Cough, usu non-productive, maybe hemoptysis
    • Lower extremity pain, swelling with above symptoms
  • Lung, cardiac, extremity exam is often normal
    • Resting, persistent tachycardia (>100)***
    • Resting, persistent tachypnea (>20min)***
    • Low grade temp maybe, but <102
    • O2 saturation may be normal: normal O2 sat does not R/O PE
    • Chest wall +/- tender - reproduces pleuritic pain
    • Anxiety - 50% with PE have it. Hyperventilation???
27
Q

PE on the ddx

A
  • Work up is tricky, extensive, radiation (chest CT w/ contrast)
  • Assess pt’s risk for PE: begin with Hx (Virchow’s Triad), PE, DDx
  • Determine a “pre-test probability” – your clinical gestalt plus a clinical prediction tool
    • “Pre-test probability”: Low, Moderate or High
  • Assign score prior to testing to help determine the probability & likelihood for Dz = “risk stratify” the pt
  • Problem: 20% of patients with a proven PE had NO risk factors
  • Lack of risk factors alone does not rule out a PE
  • Lack of risk factors affects your pre-test probability only
  • Chest CT w/ contrast PE protocol (contrast timed, thin cuts 0.3mm) is the Gold Standard test for PE
28
Q

Well’s Criteria for PE

A
  • Assign a score:
  • Signs/Sx’s DVT - 3pts
  • PE #1 Dx – 3pts
  • Heart rate >100 - 1.5pts
  • Immobilization 3 days or surgery <1mo - 1.5pts
  • Hx proven PE/DVT-1.5pts
  • Hemoptysis – 1pt
  • Active malignancy – 1pt
  • Three tier model:
  • Low prob = <2 pts (1.3%)
  • Moderate = 2-6 pts (16.2%)
  • High prob = >6 pts (37.5%)
  • Two tier model
  • “PE Unlikely” = 0-4 pts (12%)
  • “PE Likely” = >4 pts (37%)
29
Q

PERC score - the LOW RISK PATIENT

A
  • PE rule-out criteria
  • MUST have LOW Risk and Pre-test Probability to even use this tool!
  • MUST answer YES to all questions: 1pt each
  • Score must be 8 or cannot “PERC ‘em out”
  • In “Low Risk” patient - <2% PE - if all true
  • Document PERC score
  • Age <50
  • Pulse <100
  • SaO2 >94%
  • No unilateral leg swelling
  • No hemoptysis
  • No recent trauma or surgery
  • No hx prior DVT or PE
  • No hormone use
30
Q

Can’t use the PERC criteria?

A
  • Low to Moderate risk pt (Well’s <4) that you can’t “PERC out”
  • You already have a Low to Moderate pre-test probability
    • The patient’s Well’s score for PE is 4 or less
    • PE is “unlikely” (two tier method)
  • Order a D-dimer
  • If the D-dimer is normal: 98% had no PE in this study
  • If the D-dimer is positive (>500): You now have to test for a PE
    • Chest CT w/ contrast, PE protocol
  • The Christopher Study
31
Q

ED work-up of PE

A
  • Chest Xray - often non-specific
    • Hamptom’s hump, Westermark’s sign (both late findings)
  • EKG - often non-specific, sinus tach, S1Q3T3 in 15% 
  • Labs, lactic acid, PT/INR
  • D-Dimer – low-moderate risk and low pre-test probability patients only
  • Bedside ULS and/or formal doppler ULS for DVT; bedside echo for right heart strain, “D” sign
  • Treatment if PE present:
    • Low-molecular weight heparin*
    • Admit
  • Stool guaiac before treatment!
  • Heparin also acceptable. Some new anticoagulants being considered as first line treatment for PE

Echo with Right Heart Strain: RA & RV enlargement; “bowing” of R ventricle – the “D” sign – highly suggestive

32
Q

PE summary - ED decision making

A
  • Low risk and low PTP? PERC score 8? <2% have PE
  • Low Risk/PTP but can’t PERC ‘em out?
    • D-dimer
    • Lower extremity doppler ultrasound for DVT
    • If both negative – done – unlikely PE
    • “Practitioner gestalt” – valuable (but takes experience)
  • Moderate (Well’s >4) to High Risk and high PTP?
    • Must perform testing for PE
    • D-dimer not useful in these patients – do not order it!
    • Ultrasound bilat lower extremities for DVT, echo for RV strain, “D” sign
    • Chest CT with contrast, PE protocol – Gold Standard test
    • Consider VQ scan: if can’t CT, allergy to contrast, new ARF (creat >2)
    • MRI may be a possibility in some centers
  • PPT = pre-test probability
  • Practitioner gestalt is still more valuable than a D-dimer
33
Q

the big 6

A
  • In every patient with chest pain, you must consider the “Big 6” – “cannot miss” diagnoses (2 A’s, 3 P’s, a B)
    • Your chart, presentation and DDx should address all of these in any patient with chest pain
  • AMI/ACS/USA - AMI/ACS/USA = Acute Myocardial Infarction/Acute Coronary Syndrome/Unstable Angina
  • Thoracic aortic dissection
  • Pericarditis/pericardial effusion
  • Pulmonary embolus
  • Pneumothorax
  • Boerhaave’s (espohageal rupture/pneumomediastinum)