Pulmonary A&P Flashcards

(55 cards)

1
Q

What involves the gas exchange pump? (conduction pathway)

A

Lung Tissue and airways
conducts airflow from outside –> alveoli and –> alveolar-capillary membrane

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2
Q

What involves the musculoskeletal ventilatory pump? what does is allow?

A

thoracic rib cage, cervical and thoracic spine, upper pelvic area and respiratory muscles
allow attachment for respiratory muscles and support/protection for lung

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3
Q

Where is the respiratory center located?

A

Medulla and Pons

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4
Q

what type of receptors respond to CO2 and pH in blood?

A

central chemoreceptors

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5
Q

What receptors can stimulate a change in RR?

A

central chemoreceptors

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6
Q

What is the primary stimulus in the control of ventilation? what is the secondary drive?

A

CO2 (CO2 and changes in pH)
O2 is secondary

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7
Q

What type of receptors in carotid and aortic arch respond to O2 and CO2

A

peripheral chemoreceptors

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8
Q

What is the pathway flow of air?

A

air in through nose or mouth
nasopharynx/oropharynx
trachea
carina (bifurcation) to many little airways
3 lobes of R or 2 lobes of L
lung tissue - parenchyma
alveoli

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9
Q

When we inhale the diaphragm ___
and the ___ muscle widens with the ribs

A

contracts and moves downward
external intercostals

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10
Q

The lower ribs do what kind of movements?

A

Lateral and A/P
bucket handle

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11
Q

The upper ribs do what kind of movements?

A

superior and outward elevation of thorax
pump handle

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12
Q

What is the function of the conducting zone? how many generation?

A

anything above bronchioles and alveoli sacs
warms and humidifies inspired air
filters and cleans
up to 16

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13
Q

How are particles trapped and taken out after breathing them in?

A

trapped in mucus
cilia moves it up and out to cough/blow nose

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14
Q

What is the function of the transitional and respiratory zone? how many generations?

A

includes respiratory bronchials and alveoli sacs
gas exchange b/w 1 alveoli and capillary
17+ generations

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15
Q

Where would you see turbulent flow in the airway?

A

trachea (big spaces)

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16
Q

Where would you expect to see laminar flow?

A

narrow airways (straight airways)

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17
Q

___: distensibility of tissues, promotes lung expansion, amount of pressure needed to expand tissues

A

compliance

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18
Q

decreased compliance = __ work = __ pressure to expand lungs

A

more work and more pressure

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19
Q

___: force which promotes return to normal, resistance to change

A

elastance

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20
Q

in an obstructive problem there is (increased or decreased) resistance?

A

increased

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21
Q

in obstructive you have decreased ___ making it harder to expand

A

estensibility? making it harder for airway to expand

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22
Q

in restrictive there is (increased or decreased) compliance?

A

decreased compliance
alveoli don’t want to open up

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23
Q

what happens to forces expiration in an obstructive disease?

A

airway starts to close down from pressure increase

24
Q

What is closing volume?
What causes this?

A

while breathing the point which the airways begins to collapse
breathing hard causes closing

25
people with COPD what happens to the airway as they breath hard over time
airway closing happens closer to quiet breathing --> air trapping
26
someone with restrictive will have (increase or decrease) lung volume? How is this related to compliance?
less volume takes more pressure to get air in leading to smaller volume in lungs
27
What is the work of breathing? What is the relationship with pressure and volume
work required to overcome airway and tissue resistance Pressure X volume (proportinal)
28
What is normal work of breathing at rest?
<5%
29
What is the function of surfactant?
provide surface stability and prevents collapse of alveolar structures
30
surfactant: increases __ of lung __ work of breaking promotes __ of alveoli
compliance decreases stability
31
surfactant: secreted by ___ helps overcome __ to allow alveoli to expand
Type 2 alveolar cells surface tension
32
When is surfactant start to be produced? When does fetus have sufficient amount for independent respiration?
24-28 weeks gestation 34-35 weeks
33
What kind of cells make up mucociliary transport and thier functions?
goblet cells: secrete mucus Ciliated epithelial cells: move fluid particulate matter stopped at multiple sites
34
What is someone mucociliary transport paralyzed, what are they at risk for?
anesthesia pneumonia
35
___: air moving in/out of lungs for distribution to alveoli
ventilation
36
__: gas transported to/from lungs and cells in blood passing through pulm capillaries for gas exchange
Perfusion
37
___: air moving to cross alveolar capillary membrane
diffusion
38
When we sit upright where is ventilation highest? Where is perfusion highest?
upper lungs weight of blood pushes down - lower lungs
39
when supine where is best ventilation and best perfusion?
ventilation: anterior perfusion: posterior
40
When we are lying on L side, where is best ventilation and perfusion?
ventilation: R lung perfusion: L lung
41
Where are you are greatest risk of pneumonia? (area of high ventilation or area of high perfusion)
area of higher perfusion because it is getting less ventilation
42
What position gives more opportunity for ventilation?
Prone
43
What is dead space? (blocked capillary)
Ventilation with no perfusion
44
What is shunt? (blocked airway)
perfusion with no ventilation
45
PEFR:
initial peak with max exhilation
46
FEV1: What is is used to evaluate?
amount exhaled after 1 second - used to evaluate bronchodilator effectiveness
47
FEV25 -75: what info?
middle 50% of exhalation info about state of small - middle sized airways
48
FVC:
total volume expired with max effort
49
What is FEV1/FVC in normal, restrictive, and obstructive?
norm: 75% restrictive: 83% obstructive: 25%
50
What is DLCO? What is it measuring? What is the norm?
diffusion capacity of the lungs for carbon monoxide overall function of the alveolar/capillary membrane 75-140% predicted
51
decreased surface ares or increased thickness of membrane will (increase or decrease) DCLO
decrease
52
What type of condition (4) will have decrease DLCO
emphysema interstitial lung disease pulmonary hypertension smoking
53
What types of conditions (3) will have increased DLCO
exercise asthma supine position
54
why does exercise increase DLCO
recruitment of capillaries
55
why does supine position increase DLCO
increased pulmonary capillary blood volume