Pulm Flashcards

1
Q

COPD CAP association

A

H. influenzae

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2
Q

Recent viral infection CAP association

A

S. aureus

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3
Q

Poor dentition/Aspiration CAP association

A

Anaerobes

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4
Q

Young healthy patient CAP association

A

Mycoplasma pneumoniae

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5
Q

Hoarseness CAP association

A

Chlamydophila pneumoniae

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6
Q

Diarrhea CAP association

A

Legionella

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7
Q

Birds CAP association

A

Chlamydia psittaci

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8
Q

Animals birthing, veterinarians, farmers CAP association

A

Coxiella burnetii

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9
Q

Hemoptysis from necrotizing disease, currant jelly sputum

A

Klebsiella pneumoniae

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10
Q

Foul-smelling sputum like rotten eggs

A

Anaerobes

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11
Q

Dry cough, rarely severe, bullous myringitis

A

Mycoplasma pneumoniae

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12
Q

Abdominal pain, diarrhea or headache and confusion

A

Legionella

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13
Q

Aids with <200 CD4 cells

A

Pneumoncystis

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14
Q

Infections associated with dry non-productive cough

A

Mycoplasma, viruses, Coxiella, pneumocystis, chlamydia

Involve interstitial space more than air space

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15
Q

Mycoplasma pneumoniae diagnostic tests

A

PCR
Cold agglutins
Serology
Eaton’s agar culture

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16
Q

Chlamydophila pneumonia diagnostic test

A

Rising Ab titers

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17
Q

Legionella diagnostic test

A

Urine antigen, culture on charcoal-yeast agar

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18
Q

Chlamydia psittaci diagnostic test

A

Rising Ab titers

19
Q

Coxiella burnetii diagnostic test

A

Rising Ab titers

20
Q

PJP diagnostic test

A

brochoalvelolar lavage with silver stain

21
Q

Outpatient tx of CAP in healthy patient with no abx in last 3 months

A

Azithromycin/clarithromycin

Doxycycline

22
Q

Outpatient tx of CAP in patient with comorbidities or abx in the last 3 months

A

Levofloxacin/moxifloxacin

23
Q

Inpatient tx of CAP

A

levoflaxacin/moxiflaxacin

ceftriaxone and azithromycin

24
Q

When to hospitalize CAP?

A
C-confusion
U-uremia
R-respiratory distress
B-BP low 
65- Age >65

2+ = hospitalization

25
Q

Hospital acquired pneumonia definition

A
  • Pneumonia developing more than 48 hours after hospitalization
  • 90 days after hospital admission
26
Q

Hospital acquired pneumonia etiology

A

E.coli or psuedomonas

27
Q

HAP treatment

A

cefepime/ceftazidine
Piperacillin/tazobactam
Carbapenem

28
Q

Treatment of ventilator associated pneumonia

A
  1. Antipseudomonal beta lactam:
    celphalosporin/zosyn/carbapenem
  2. Second antipseudomonal agent:
    gentamicin(or other amino glycoside)/flouroquinolone
  3. MRSA agent: Vancomycin or linezolid
29
Q

When to add steroids to bacterium in PCP?

A

pO2 35

30
Q

Alternative treatment for mild PCP with mild hypoxia

A

Atovoquone

31
Q

Alternative treatment for PCP with bactrim toxicity

A
  • Clindamycin and primaquine

- Pentamidine

32
Q

When to prophylax for PCP

A

CD4>200

33
Q

Alternatives to bactrim for PCP prophylaxis

A

Atovaquone or dapsone

34
Q

When/what to use for prophylaxis for atypical mycobacterium?

A

CD4 >50

Azithromycin

35
Q

Risk factors for TB

A
Immigrant in last 5 years 
Prisoners 
HIV positive
Healthcare workers 
Close contact with person with TB
Steroid use 
Hematologic malignancy 
Alcoholic 
DM
36
Q

Diagnosing TB

A

Best initial test: CXR
Sputum stain and culture for acid x3
Most accurate test: pleural biopsy

37
Q

Active TB treatment

A

2 months: Rifampin, INH, pyrazinamide, ethambutol
4 additional months: rifampin and INH

Treatment continues for 9 months if: 
Osteomyelitis 
Miliary TB
Meningitis 
Pregnancy or other contraindication for pyrasinamide
38
Q

Rifampin toxicity

A

Red color to body secretions

No need to stop therapy

39
Q

Isoniazid toxicity

A

Peripherla neuropathy

Use pyridoxine to prevent

40
Q

Pyrazinamide toxicity

A

Hyperuricemia

No need to treat unless symptomatic

41
Q

Ethambutol toxicity

A

Optic neuritis/color vision

Management: decrease dose in renal failure

42
Q

Induration >5mm positive

A
HIV
Glucocorticoid user 
Close contact with TB 
Abnormal calcifications on CXR
Organ transplant recipient
43
Q

Induration >10mm positive

A
Immigrant in last 5 years 
Prisoner 
Healthcare worker 
Close contact with TB 
Hematologic malignancy 
Alcoholic 
DM
44
Q

Treatment of Pulmonary hypertension

A

Prostacyclin analogues (PA vasodilators): epoprostenol, treprostinil, iloprost, beraprost

Endothelin antagonists: bosetan

PDE inhibitor: sildenafil