Cards Flashcards
CC: Chest pain
PE: Chest wall tenderness
Diagnosis?
Accurate test?
Costochondritis
No additional testing
CC: Chest pain w/ radiation to back
PE: Unequal blood pressure between arms
Diagnosis?
Accurate test?
Aortic Dissection
CXR: Widened mediastinum
Confirmatory: CT/MRI/TEE
CC: Chest pain in person under 40yo
PE: Replicate pain with lying flat, improve with sitting up
Diagnosis?
Accurate test?
Pericarditis
ECG: ST elevations everywhere with PR depressions
CC: Chest pain sudden onset with SOB
PE: tachycardic, hypoxic
Diagnosis?
Accurate test?
Pulmonary embolism
Spiral CT or VQ scan
Niacin- effect and adverse effects
Excellent at adding to Statin for lipid control, increase HDL
AE: elevation in glucose and uric acid, pruritus
Statin- effect and adverse effects
HMG-CoA reductase inhibitor, lowers LDL
Antioxidant effect on endothelial lining
AE: elevations in LFTs (monitor), myositis
Gemfibrozil- effect and adverse effects
Fibric acid derivative, lowers TG. No mortality benefit.
AE: Enhances statins myositis
Cholestryamine- effect and adverse effects
Bile acid sequester ant
AE: GI discomfort- flatus and cramps
Reduces absorption of other medications from gut
Ezetimibe- effect and adverse effects
Lowers LDL, no effect on anything
Essentially useless
Well tolerated
Dihydropyridine CCB (all the ones that end in -dipine)- effect
Decrease vascular resistance, negative inotrope
Causes reflex tachycardia- increasing myocardial oxygen demand
**increase mortality in CAD
Non-dihydropyridine CCB (verapamil and diltiazem) - effect
Cardiac specific- reduce myocardial oxygen demand and vasospasm.
Used in with CAD when: Severe asthma limits use of BB Pinzmetal variant angina Cocaine induced chest pain Inability to control pain despite max medical management
***Does NOT lower mortality risk
Side effects of CCB
Edema
Constipation
Heart block
Increased prolactin (only verapamil)
Extra heart sound right before S1
S4- indicated atrium contracting against stiffen ventricle
May be present during infarction or ventricular hypertrophy
Extra heart sound right after S2
S3- turbulent flow into ventricles
May be present in diastolic heart failure
> 10mmHg decrease in BP on inhalation
Pulsus paradoxus
Associated with cardiac tamponade
Triphasic scratchy sound on auscultation
Pericardial friction rub
Associated with pericarditis
Contraindications to thrombolytics
Major bleeding: Melena or Any brain bleed
Surgery in last 2 weeks
BP >180/110
Nonhemorrhagic stroke in last 6mo
***If thrombolytics contraindicated- transfer to facility that performs PCI
ACS- Aspirin
Every patient prior to revascularization
***Improves mortality
ACS-Clopidigrel
If aspirin is not tolerated
Always if patient undergoes stenting or angioplasty
ACS- Beta blockers
Every patient- improves mortality
Not time sensitive-just start any time after admission
ACS- ACE/ARB
Every patient- improves mortality
Best results if EF<40%, not time sensitive
ACS- Statins
Every patient
Best benefit with LDL >100