EM Flashcards
Ingestion </= 2 hours
Gastric lavage
50%-1 hour
15%- 2 hours
Never try to induce vomiting, it takes 15-20 minutes to work and delays antidote
Contraindicated:
Altered mental status- aspiration
Caustic agent-burns
Ipecac for overdose
Do not use
Takes 15-20 min to induce vomiting
Cathartics (sorbitol, Mg sulfate/citrate) for overdose
Always WRONG
speeding up GI transit time does not eliminate ingestion
Forced diuresis for overdose
WRONG
Whole bowel irrigations for overdose
Place NGT-administer GOLYTELY
Only for: massive iron ingestion, lithium, swallowing drug filled packet
Opiate overdose
Naloxone
Overdose is fatal
Withdrawal is not
Slurred speech Unsteady gait Drowsiness Normal pupil size Mild decrease in respirations
Benzo overdose - not fatal
Do not give flumazenil- seizures
Charcoal in overdose
Benign and should be used in all patients with pill overdose
Decreases toxin level even once drug is absorbed
Acetaminophen overdose
Clear toxic dose (>8mg)- N-acetylcysteine
Unclear dose: Activated charcoal, obtain a acetaminophen level at 4 hours, repeat level at 2 hours, based on two data points determine necessity of n-acetylcysteine within 8 hours of ingestion
24 hours after ingestion- no therapy
Tinnitus hyperventilation
Respiratory alkalosis progression to anion metabolic acidosis
Renal toxicity
Altered mental status
Aspirin toxicity
Alkalize urine to increase rate of aspirin excretion
TCA toxicity
Fatality from: seizures and prolonged QT causing arrhythmias
Anticholinergic effects: dry mouth, constipation, urinary retention (do not need to treat because not fatal)
Tx: sodium bicarbonate- protects the heart against arrhythmias, does not improve urinary excretion
Carbon monoxide poisoning
Carboxyhemoglobin- same as being super anemic Dyspnea Light headed Confusion Seizures MI Lactic acidosis
Dx: carboxyhemoglobin level, normal PaO2, but lactic acidosis
Tx: 100% O2, if severe hyperbaric chamber
Methemoglobinemia
Hemoglobin oxidized in ferric state
Will not carry oxygen- brown
Caused by: benzocaine, nitrites, nitroglycerin, and dapsone
Dyspnea Cyanosis Confusion Seizures Lactic acidosis
Dx: methemoglobin level, normal PaO2, but lactic acidosis
Tx: 100% O2 and methylene blue
Organophosphate/Never gas poisoning
Acetyhcholinesterase inhibitors Salvation Lacrimation Polyuria Diarrhea Bronchospasm, bronchorrhea, respiratory distress
Tx:
Atropine
Remove clothing
Pralidoxime (reactive acetylcholinesterase, takes a while to work)
Digoxin toxicity
Hypokalemia predisposes
GI problems: N/V, anorexia, abdominal pain
Hyperkalemia
Confusion
Visual disturbances
Rhythm disturbances- any arrhythmia is possible, atrial tachycardia with AV block most common
Dx: Digoxin leve
Tx: Control potassium, Digoxin specific antibody