Pul 7 - PE, DVT, Pneumothorax Flashcards
What are some pathologies that cause hypercoagulatbility?
- Sickle cell.
- Polycythemia.
- CHF.
- Estrogen excess.
- Cancer.
- Pregnancy.
- OCPs.
- Smoking.
What would be a state that would have all the three components of Virchow’s triad?
Postpartum.
What are the symptoms of DVT?
- Swollen foot/ankle (unilateral); (bilateral seen heart failure).
- +/-(may or may not) Pain.
- +/- Homan’s sign (pain w/ ankle dorsiflexion).
- +/- palpable cord.
How do we diagnose DVT?
- First consider if it is high or low probability.
- High prob: huge leg, history of cancer, or other coagulation prob. Use compression ultrasound: if the vein is hard and blood doesn’t move around, then you have a DVT.
- Low prob: If patient has a leg that isn’t swollen much, detect D-dimer: a fibrin degradation product that is elevated when plasmin is dissolving a clot. It is nonspecific, but if D-dimer is negative, DVT ruled-out.
How do we prevent DVT?
- Heparin.
- Low molecular weight heparin, like Enoxaparin.
- SCD: sequential compression devices, goes over calves and they inflate.
- Compression stockings.
What is the treatment for DVT?
Heparin until warfarin therapeutic.
What are the symptoms of pulmonary embolism (PE)?
- Pleuritic chest pain (Pain when inhaling).
- Shortness of breath.
- Cough.
- Hemoptysis (rare).
- Fever.
- Tachypnea.
- AMS/confusion (Altered mental status).
The last three are the most common symptoms.
How do we diagnose pulmonary embolism?
- Elevated D-dimer.
- +/- DVT on LE (lower extremity) US (ultrasound).
- Large A-a gradient on ABG (arterial blood gas).
- +/- EKG changes (S1Q3T3 - wide S in lead I, large Q and inverted T in lead III).
- CT scan.
- V/Q scan - centigraphy.
- Pulmonary angiogram = Gold standard
What is a saddle embolus?
The embolus is stuck in the bifurcation of the pulmonary arteries. Death is instantaneous.
What is the treatment for pulmonary embolism?
Consider thrombolysis, but usually just heparin/warfarin.
What are fat embolus associated with?
- Long bone fracture.
2. Liposuction.
What are amniotic fluid embolus associated with?
It can lead to DIC postpartum.
What is air embolus associated with?
Caisson disease (the bends”: decompression sickness from rising too quickly while scuba diving).
- IV
- Too much pressure form ventilator.
What are bacterial embolus associated with?
Bacterial endocarditis.
What is a pnemothorax?
Abnormal collection of air in the pleural space.