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GI Pharm > PUD Drugs > Flashcards

PUD Drugs Flashcards

1
Q

H. pylori Triple combination Tx

A

Omeprazole
Amoxicillin
Clarithromycin

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2
Q

Triple combo Tx MOA

A

Reduce gastric pH; Abx action of H. pylori

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3
Q

Triple combo Tx indication

A

H. pylori associated ulcers

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4
Q

H. pylori Quadruple combination Tx

A

Omeprazole
Metronidazole
Tetracycline
Bismuth

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5
Q

Ranitidine class

A

H2RB

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6
Q

Ranitidine MOA

A

Competitively inhibits H2Rs in gastric parietal cells reducing basal and stimulated acid secretion

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7
Q

Ranitidine indication

A

PUD, GERD

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8
Q

Ranitidine side effect

A

Possible B12 deficiency with long term use

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9
Q

When should you take Ranitidine?

A

~1900h

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10
Q

Omeprazole class

A

PPI

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11
Q

Omeprazole MOA

A

Reduces basal and stimulated gastric parietal cell proton pump acid secretion

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12
Q

Omeprazoel indication

A

PUD, GERD, NSAID ulcer Px, Stress ulcer Px in critically ill

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13
Q

Omeprazole side efect

A

May cause gastric atrophy/B12 deficiency in long term use

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14
Q

Omeprazole Dx-Dx

A

May decrease absorption of Fe, Zn, Ca++

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15
Q

Pantoprazole class

A

PPI

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16
Q

Pantoprazole has the least effect on this med, compared to other PPIs…

A

Clopidrogrel

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17
Q

Sucralfate class

A

Mucosal surfactant

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18
Q

Sucralfate MOA

A

Forms a paste and selectively binds to ulcers and erosions; stimulates mucus, bicarb, and prostaglandin secretion

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19
Q

Sucralfate indication

A

Duodenal and gastric ulcers

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20
Q

Sucralfate side effect

A

Constipation

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21
Q

After taking Sucralfate, how long do you have to wait to take nay other meds?

A

2 hours

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22
Q

What element does Sucralfate contain?

A

Al

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23
Q

Who needs to avoid the Al?

A

Renal failure Pts

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24
Q

Dicyclomine class

A

Muscarinic antagonist

25
Q

Dicyclomine MOA

A

M receptor anticholinergic drug

26
Q

Dicyclomine indication

A

IBS cramps

27
Q

Dicyclomine side effect

A

Dry mouth

28
Q

Dicyclomine contraindication

A

Glaucoma

29
Q

Alternagel class

A

Antacid

30
Q

Alternagel MOA

A

Neutralizes HCl to AlCl3 and H2O

31
Q

Alternagel indication

A

Hyperacidity

32
Q

Alternagel side effect

A

hypophosphatemia

33
Q

Alternalgel contraindication

A

Al allergy

34
Q

Alternalgel Dx-Dx

A

Binds to and inhibits absorption of many drugs

35
Q

MOM class

A

Antacid

36
Q

MOM MOA

A

Reacts with HCl to form MgCl; osmotic absorption of fluids distends colon and increases peristalsis

37
Q

MOM indication

A

Dyspepsia, constipation

38
Q

MOM side effect

A

Diarrhea

39
Q

MOM Dx-Dx

A

Binds to and inhibits absorption of many drugs

40
Q

Cytotec class

A

NSAID protectant

41
Q

Cytotec MOA

A

Replaced prostaglandins

42
Q

Cytotec indication

A

NSAID associated ulcers, Pts taking NSAIDs at high risk of gastric bleeding

43
Q

Cytotec pregnancy class

A

X - abortifactant

44
Q

Saxenda class

A

GLP-1 Receptor Agonist; Wt loss drug

45
Q

Saxenda MOA

A

Increases insulin secretion
Decreases glucagon secretion
Decreases gastric emptying and food intake

46
Q

Saxenda indication

A

T2DM adjunct therapy, Wt loss

47
Q

Saxenda side effect

A

hypoglycemia

48
Q

Saxenda pregancy class

A

X

49
Q

D/C Saxenda if you haven’t lost at least _____ of your body wt in ______.

A

4%

16 weeks

50
Q

Orlistat class

A

Lipase inhibitor; Wt loss drug

51
Q

Orlistat MOA

A

Reversibly inhibits lipase secretion, reducing fat absorption by ~30%

52
Q

Orlistat indication

A

Obesity management in Pts with a BMI >30 or >27 with risk factors

53
Q

Orlistat side effect

A

Oily rectal discharge

54
Q

I’m sorry, I’m sorry, what did you say could happen on Orlistat?

A

I said oily rectal discharge

55
Q

I would rather wreck myself at the gym

A

But we all make choices

56
Q

Orlistat pregnacny class

A

X

57
Q

D/C Orlistat in _____ if you haven;t lost at least _____ of your body wt.

A

12 weeks

5%

58
Q

All that oily rectal discharge, and I didn’t even loose 5%.

A

Ain’t that a kick in the oily pants

GI Pharm (5 decks)

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