PUD Drugs Flashcards by E D

H. pylori Triple combination Tx

Omeprazole
Amoxicillin
Clarithromycin

How well did you know this?

Not at all

Perfectly

Triple combo Tx MOA

Reduce gastric pH; Abx action of H. pylori

How well did you know this?

Not at all

Perfectly

Triple combo Tx indication

H. pylori associated ulcers

How well did you know this?

Not at all

Perfectly

H. pylori Quadruple combination Tx

Omeprazole
Metronidazole
Tetracycline
Bismuth

How well did you know this?

Not at all

Perfectly

Ranitidine class

H2RB

How well did you know this?

Not at all

Perfectly

Ranitidine MOA

Competitively inhibits H2Rs in gastric parietal cells reducing basal and stimulated acid secretion

How well did you know this?

Not at all

Perfectly

Ranitidine indication

PUD, GERD

How well did you know this?

Not at all

Perfectly

Ranitidine side effect

Possible B12 deficiency with long term use

How well did you know this?

Not at all

Perfectly

When should you take Ranitidine?

~1900h

How well did you know this?

Not at all

Perfectly

Omeprazole class

PPI

How well did you know this?

Not at all

Perfectly

Omeprazole MOA

Reduces basal and stimulated gastric parietal cell proton pump acid secretion

How well did you know this?

Not at all

Perfectly

Omeprazoel indication

PUD, GERD, NSAID ulcer Px, Stress ulcer Px in critically ill

How well did you know this?

Not at all

Perfectly

Omeprazole side efect

May cause gastric atrophy/B12 deficiency in long term use

How well did you know this?

Not at all

Perfectly

Omeprazole Dx-Dx

May decrease absorption of Fe, Zn, Ca++

How well did you know this?

Not at all

Perfectly

Pantoprazole class

PPI

How well did you know this?

Not at all

Perfectly

Pantoprazole has the least effect on this med, compared to other PPIs…

Clopidrogrel

How well did you know this?

Not at all

Perfectly

Sucralfate class

Mucosal surfactant

How well did you know this?

Not at all

Perfectly

Sucralfate MOA

Forms a paste and selectively binds to ulcers and erosions; stimulates mucus, bicarb, and prostaglandin secretion

How well did you know this?

Not at all

Perfectly

Sucralfate indication

Duodenal and gastric ulcers

How well did you know this?

Not at all

Perfectly

Sucralfate side effect

Constipation

How well did you know this?

Not at all

Perfectly

After taking Sucralfate, how long do you have to wait to take nay other meds?

2 hours

How well did you know this?

Not at all

Perfectly

What element does Sucralfate contain?

How well did you know this?

Not at all

Perfectly

Who needs to avoid the Al?

Renal failure Pts

How well did you know this?

Not at all

Perfectly

Dicyclomine class

Muscarinic antagonist

Dicyclomine MOA

M receptor anticholinergic drug

Dicyclomine indication

IBS cramps

Dicyclomine side effect

Dry mouth

Dicyclomine contraindication

Glaucoma

Alternagel class

Antacid

Alternagel MOA

Neutralizes HCl to AlCl3 and H2O

Alternagel indication

Hyperacidity

Alternagel side effect

hypophosphatemia

Alternalgel contraindication

Al allergy

Alternalgel Dx-Dx

Binds to and inhibits absorption of many drugs

MOM class

Antacid

MOM MOA

Reacts with HCl to form MgCl; osmotic absorption of fluids distends colon and increases peristalsis

MOM indication

Dyspepsia, constipation

MOM side effect

Diarrhea

MOM Dx-Dx

Binds to and inhibits absorption of many drugs

Cytotec class

NSAID protectant

Cytotec MOA

Replaced prostaglandins

Cytotec indication

NSAID associated ulcers, Pts taking NSAIDs at high risk of gastric bleeding

Cytotec pregnancy class

X - abortifactant

Saxenda class

GLP-1 Receptor Agonist; Wt loss drug

Saxenda MOA

Increases insulin secretion Decreases glucagon secretion Decreases gastric emptying and food intake

Saxenda indication

T2DM adjunct therapy, Wt loss

Saxenda side effect

hypoglycemia

Saxenda pregancy class

D/C Saxenda if you haven't lost at least _____ of your body wt in ______.

4% | 16 weeks

Orlistat class

Lipase inhibitor; Wt loss drug

Orlistat MOA

Reversibly inhibits lipase secretion, reducing fat absorption by ~30%

Orlistat indication

Obesity management in Pts with a BMI >30 or >27 with risk factors

Orlistat side effect

Oily rectal discharge

I'm sorry, I'm sorry, what did you say could happen on Orlistat?

I said oily rectal discharge

I would rather wreck myself at the gym

But we all make choices

Orlistat pregnacny class

D/C Orlistat in _____ if you haven;t lost at least _____ of your body wt.

12 weeks | 5%

All that oily rectal discharge, and I didn't even loose 5%.

Ain't that a kick in the oily pants