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GI Pharm > Pancreatic Drugs > Flashcards

Pancreatic Drugs Flashcards

1
Q

Viokase: class

A

Pancreatinc enzymes

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2
Q

Viokase: class

A

Pancreatinc enzymes

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3
Q

Viokase: MOA

A

Supplemental lipase, amylase, protease

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4
Q

Viokase: indication:

A

Chronic pancreatitis

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5
Q

Viokase: contraindication

A

Acute or exacerbation of chronic pancreatitis

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6
Q

What does dairy do to Viokase?

A

Decreases efficacy

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7
Q

Demerol: class

A

Analgesic

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8
Q

Demerol: MOA

A

Binds to mu receptors in CNS and inhibits ascending pain pathways

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9
Q

Demerol: indications

A

Short term peri-op and acute pacreatitis

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10
Q

Demerol: side effects

A

CNS depression, HOTN, seizures from toxic metabolite

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11
Q

Demerol: Contraindication

A

Renal disease, elderly, recent MAOI use

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12
Q

How long should you limit the use of Demerol to?

A
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13
Q

Octreotide: class

A

Somatostatin analogue

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14
Q

Octreotide: MOA

A

Inhibits bowel secretions
Dose related effect on motility
Splanchnic arteriole contraction

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15
Q

Octreotide: indication

A

Diarrhea secondary to bowel dysmotility, carcinois,

VIP-oma, vagotomy, dumping syndrome, short bowel syndrome, HIV diarrhea, GI bleed

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16
Q

Octreotide: Side efects

A

Steatorrhea, Gallstones (>50% in long term use)

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17
Q

Octreotide: contraindication

A

Bowel obstruction

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18
Q

Octreotide: Dx-Dx

A

insulin, PO hypoglycemics, BBs, CCBs

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19
Q

Ranitidine: class

20
Q

Ranitidine: MOA

A

Competitively inhibits H2Rs in gastric parietal cell reducing basal and stimulated acid production

21
Q

Ranitidine: indications

22
Q

Ranitidine: side effect

A

Possible B12 deficiency in long term use

23
Q

Omeprazole: class

24
Q

Omeprazole: MOA

A

Reduces basal and stimulated parietal cell proton pump acid secretion

25
Q

Omeprazole: indications

A

PUD, GERD, NASID ulcer Px, stres ulcer Px in critically ill

26
Q

Omeprazole: side effects

A

Possible gastric atrophy and/or B12 deficiency in long term use

27
Q

Omeprazole: Dx-Dx

A

May decrease Fe/Zn/Ca++ absorption

28
Q

Pantoprazole: class

29
Q

What drug does Pantoprazole have little effect on, compared to Omeprazole?

A

Clopidogrel

30
Q

What time is gastric acid at it’s highest?

31
Q

When should you take H2RBs and PPIs?

32
Q

Primaxin: class

33
Q

Primaxin: MOA

A

Lyses bacterial cells

34
Q

Primaxin: indication

A

Intra abd infection, liver abscess

35
Q

Primaxin: contraindication

A

Sensitivity to IM Lidocaine

36
Q

Cipro: class

37
Q

Cipro: MOA

A

Inhibits DNA gyrase

38
Q

Cipro: indication

A

Mild diverticulitis

Traveler’s diarrhea

39
Q

Cipro: contraindications

40
Q

Metronidazole: class

41
Q

Metronidazole: MOA

A

Inhibits bacterial protein synthesis

42
Q

Metronidazole: indication

A

Diverticulitis, C. diff

43
Q

Metronidazole pregnancy category

44
Q

Vancomycin: class

45
Q

Vancomycin: MOA

A

Inhibits glycopeptide polymeration, inhibiting bact cell wall synthesis

46
Q

Vancomycin: indication

A

Staph enetrocolitis, C. diff

47
Q

Vancomycin: side effects

A

PO: bitter taste
IV: nephro/neuro/ototoxicity, Red Man Syndrome

GI Pharm (5 decks)

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