Pancreatic Drugs Flashcards
Viokase: class
Pancreatinc enzymes
Viokase: class
Pancreatinc enzymes
Viokase: MOA
Supplemental lipase, amylase, protease
Viokase: indication:
Chronic pancreatitis
Viokase: contraindication
Acute or exacerbation of chronic pancreatitis
What does dairy do to Viokase?
Decreases efficacy
Demerol: class
Analgesic
Demerol: MOA
Binds to mu receptors in CNS and inhibits ascending pain pathways
Demerol: indications
Short term peri-op and acute pacreatitis
Demerol: side effects
CNS depression, HOTN, seizures from toxic metabolite
Demerol: Contraindication
Renal disease, elderly, recent MAOI use
How long should you limit the use of Demerol to?
Octreotide: class
Somatostatin analogue
Octreotide: MOA
Inhibits bowel secretions
Dose related effect on motility
Splanchnic arteriole contraction
Octreotide: indication
Diarrhea secondary to bowel dysmotility, carcinois,
VIP-oma, vagotomy, dumping syndrome, short bowel syndrome, HIV diarrhea, GI bleed
Octreotide: Side efects
Steatorrhea, Gallstones (>50% in long term use)
Octreotide: contraindication
Bowel obstruction
Octreotide: Dx-Dx
insulin, PO hypoglycemics, BBs, CCBs