Pancreatic Drugs

Question 1

Viokase: class

Answer 1

Pancreatinc enzymes

Question 2

Viokase: class

Answer 2

Pancreatinc enzymes

Question 3

Viokase: MOA

Answer 3

Supplemental lipase, amylase, protease

Question 4

Viokase: indication:

Answer 4

Chronic pancreatitis

Question 5

Viokase: contraindication

Answer 5

Acute or exacerbation of chronic pancreatitis

Question 6

What does dairy do to Viokase?

Answer 6

Decreases efficacy

Question 7

Demerol: class

Answer 7

Analgesic

Question 8

Demerol: MOA

Answer 8

Binds to mu receptors in CNS and inhibits ascending pain pathways

Question 9

Demerol: indications

Answer 9

Short term peri-op and acute pacreatitis

Question 10

Demerol: side effects

Answer 10

CNS depression, HOTN, seizures from toxic metabolite

Question 11

Demerol: Contraindication

Answer 11

Renal disease, elderly, recent MAOI use

Question 12

How long should you limit the use of Demerol to?

Question 13

Octreotide: class

Answer 13

Somatostatin analogue

Question 14

Octreotide: MOA

Answer 14

Inhibits bowel secretions
Dose related effect on motility
Splanchnic arteriole contraction

Question 15

Octreotide: indication

Answer 15

Diarrhea secondary to bowel dysmotility, carcinois,

VIP-oma, vagotomy, dumping syndrome, short bowel syndrome, HIV diarrhea, GI bleed

Question 16

Octreotide: Side efects

Answer 16

Steatorrhea, Gallstones (>50% in long term use)

Question 17

Octreotide: contraindication

Answer 17

Bowel obstruction

Question 18

Octreotide: Dx-Dx

Answer 18

insulin, PO hypoglycemics, BBs, CCBs

Question 19

Ranitidine: class

Answer 19

H2RB

Question 20

Ranitidine: MOA

Answer 20

Competitively inhibits H2Rs in gastric parietal cell reducing basal and stimulated acid production

Question 21

Ranitidine: indications

Answer 21

PUD, GERD

Question 22

Ranitidine: side effect

Answer 22

Possible B12 deficiency in long term use

Question 23

Omeprazole: class

Answer 23

PPI

Question 24

Omeprazole: MOA

Answer 24

Reduces basal and stimulated parietal cell proton pump acid secretion

Question 25

Omeprazole: indications

Answer 25

PUD, GERD, NASID ulcer Px, stres ulcer Px in critically ill

Question 26

Omeprazole: side effects

Answer 26

Possible gastric atrophy and/or B12 deficiency in long term use

Question 27

Omeprazole: Dx-Dx

Answer 27

May decrease Fe/Zn/Ca++ absorption

Question 28

Pantoprazole: class

Answer 28

PPI

Question 29

What drug does Pantoprazole have little effect on, compared to Omeprazole?

Answer 29

Clopidogrel

Question 30

What time is gastric acid at it's highest?

Answer 30

1900h

Question 31

When should you take H2RBs and PPIs?

Answer 31

1800h

Question 32

Primaxin: class

Answer 32

Abx

Question 33

Primaxin: MOA

Answer 33

Lyses bacterial cells

Question 34

Primaxin: indication

Answer 34

Intra abd infection, liver abscess

Question 35

Primaxin: contraindication

Answer 35

Sensitivity to IM Lidocaine

Question 36

Cipro: class

Answer 36

FQ Abx

Question 37

Cipro: MOA

Answer 37

Inhibits DNA gyrase

Question 38

Cipro: indication

Answer 38

Mild diverticulitis | Traveler's diarrhea

Question 39

Cipro: contraindications

Answer 39

Age

Question 40

Metronidazole: class

Answer 40

Abx

Question 41

Metronidazole: MOA

Answer 41

Inhibits bacterial protein synthesis

Question 42

Metronidazole: indication

Answer 42

Diverticulitis, C. diff

Question 43

Metronidazole pregnancy category

Answer 43

B

Question 44

Vancomycin: class

Answer 44

Abx

Question 45

Vancomycin: MOA

Answer 45

Inhibits glycopeptide polymeration, inhibiting bact cell wall synthesis

Question 46

Vancomycin: indication

Answer 46

Staph enetrocolitis, C. diff

Question 47

Vancomycin: side effects

Answer 47

PO: bitter taste IV: nephro/neuro/ototoxicity, Red Man Syndrome