Public Health Flashcards
What is health?
A state of complete physical, mental and social well-being and not merely the absence of disease
3 areas of public health and 1 example of each
Health protection - environmental disasters
Health improvement - lifestyle e.g. change for life
Improving services - audit and evaluation
What is primary disease prevention? give 1 example
Aims to prevent a disease before it ever happens. Changes peoples exposure to a risk
Immunisation, fluoridation of water
What is secondary disease prevention? give 1 example
Aims to detect disease early to alter the course/slow progression
Screening, aspirin after an MI
What is tertiary disease prevention? give 1 example
Aims to reduce disability and minimise complications
stroke rehab
What is the prevention paradox?
If something brings a lot of benefit to a population it likely provides little benefit to the individual
10 screening criteria
Important problem, recognised early stage, natural history known, suitable test, acceptable to population, continuous process, facility to diagnose and treat, agreed policy on who to treat, acceptable treatment, cost effective
What 3 things form the triple assessment for breast cancer screening?
Imaging - USS & mammography
Clinical assessment
Biopsy
When does breast cancer screening take place?
Every 3 years between the ages of 50 and 70
When does cervical cancer screening take place?
ages 25-50 every 3 years
ages 50-64 every 5 years
9 things on the newborn heel prick test
MCADD, sickle cell, CF, congenital hypothyroid, maple syrup disease, PKU, Glutamic acidaemia, isovaleric acidaemia, homocysteine uria
What are the 2 ways of monitoring prevalence?
Active and passive
Describe the difference between active and passive prevalence monitoring
Active - seeking out people with the disease
Passive - data taken from sentinel GP practices
Define sensitivity
The proportion of people with the disease who are correctly identified by the screening
Define specificity
The proportion of people who do not have the disease who are correctly excluded by the screening
Define PPV
Proportion of people who have a positive screening result who actually have the disease
Define NPV
Proportion of people who have a negative screening result who do not have the disease
3 biases associated with screening
Selection bias
Length time bias
Lead time bias
Define length time bias
Screening is more likely to pick up long lived slow growing tumours than short lived aggressive ones due to the timings
Define lead time bias
Overestimation of survival duration due to earlier detection by screening than clinical presentation
What is epidemiology?
Study of frequency, distribution and determinants of disease in populations in order to prevent and control disease
Define prevalence
Number of existing cases in a defined population at a defined point in time divided by the number of people in a population
Prevalence ratio
Prevalence in exposed divided by prevalence in unexposed
5 reasons for association between 2 variables
True association, reverse causality, chance, bias, confounding
8 elements of communicable disease control
Surveillance, epidemiology, incubation periods, outbreak management , diseases, immunisations, healthcare associated infections and emerging disease
Define communicable disease
A disease which can be transferred from one person to another
6 methods of preventing disease transmission
Vaccination, education, prophylaxis, contact tracing, monitoring, treatment
What is the chain of infection
Reservoir - portal of exit - agent - mode of transmission - portal of entry - host - person to person spread
3 types of transmission and an example for each
Direct - STIs
Indirect - malaria
Airborne - TB
Define endemic
Persistent level of disease occurrence
Define hyper-endemic
Persistently high levels of disease occurence
Define sporadic
Irregular pattern of disease occurrence
Define epidemic
Occurrence within an area in excess of expected for given time
Define pandemic
Epidemic widespread over several countries
Define cluster
Aggregation of cases which may or may not be linked
3 reasons for surveillance
Establish baseline rate, allow identification of outbreaks, monitor efficacy or immunisation programmes
Define outbreak
2 or more cases that are linked or occurrence of a disease in an area that isn’t expected
Define common source outbreak
A group of people exposed to a common source of infectious agent
4 methods of surveillance
Passive, sentinel, active, enhanced
What is gillick competence?
A child under 16 is able to give consent for medical treatment without the need for parental permission and knowledge
5 Fraser guidelines
Girl will understand advice, can’t be persuaded to tell parents, likely to carry on having sex anyway, physical/mental health likely to suffer, best interests
Descrive a case control study
Population split into cases and controls and looks at exposures in both groups, usually retrospective
Describe a cohort study
An observational study where the population split into exposed and unexposed and looks at who gets the disease in both groups - usually prospective
What is an ecological study
A study carried out at population rather than individual level
What is a cross sectional study
Measures frequency and examines distribution and determinants, can be descriptive or analytical
Pros and cons of a cohort study
+ves - best for common outcomes, yields true incidence and relative risks
-ves expensive, requires large numbers, prone to bias in change of methods over time
Pros and cons of a case control study
+ves - good for rare outcomes, relatively inexpensive, small numbers and quick to complete
-ves - prone to selection bias, prone to recall bias
Pros and cons of a RCT
+ves - minimises bias and confounders, multiple outcomes can be studied, strong evidence of causal relationships can be provided
-ves - expensive, ethical concerns, large drop outs, conflicting evidence from trials occurs