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phase 3b > Derm Pathology > Flashcards

Derm Pathology Flashcards

(65 cards)

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1
Q

What is a malignant melanoma

A

invasive malignant tumour of epidermal melanocytes which has potential to metastasize

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2
Q

what is this

A

pustular psoriasis

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3
Q

What is a squamous cell carcinoma

A

locally invasive malignant tumour of epidermal keratinocytes or its appendages

has potential to met

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4
Q

What is a basal cell carcinoma

A

slow growing locally invasive malignant tumour of epidermal keratinocytes

most common malignant skin tumour, rarely mets

normally in older people

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5
Q

what is shingles

A

reactivation of dormant virus in posterior root ganglion

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6
Q

what is this

A

nodular basal cell carcinoma

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7
Q

Management of scabies

A

scabicide - permethrin or malathion

antihistamines

washing bedding and clothes

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8
Q

Presentation of SCC

A

keratotic (scaly/crusty) ill defined nodule which may ulcerate

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9
Q

What is this

A

ringworm/tinea corporis

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10
Q

what is this

A

nail changes in psoriasis - pitting

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11
Q

what is this

A

malignant melanoma

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12
Q

eczema presentation

A

itchy, erythematous dry scaly patches

child: face and extensors
adults: flexors

scratching -> excoriations and lichenfication

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13
Q

what is this

A

chicken pox

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14
Q

what is this

A

flexural psoriasis

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15
Q

how does shingles present

A
  • tired
  • unilateral scabs - polymorphic red papules
  • pain/burning/itchy
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16
Q

What is this

A

lichen planus

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17
Q

what is this

A

scabies

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18
Q

What is this

A

pitryiasis versicolor

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19
Q

Causes of acne

A
  • hormonal
  • increased sebum production
  • abnormal follicular keratinization
  • bacterial colonization
  • inflammation
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20
Q

what is this

A

urticaria

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21
Q

describe and identify this

A

impetigo

honey coloured crusts on erythematous base

well defined lesions

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22
Q

What is lichen planus?

A

chronic inflammatory and immune mediated disease

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23
Q

what is this

A

plaque psoriasis

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24
Q

what is this

A

Pityriasis rosea

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25
what is this
guttate psoriasis - raindrops
26
Management of shingles
aciclovir
27
How does urticaria present?
itchy stinging/burning rash
28
What is prognosis based on for BCC and SCC
tumour size, site, growth pattern, failure of previous treatment, immunosuppresion
29
Impetigo management
Topical fusidic acid PO Abx (fluclox) if severe
30
Acne Management
* topical - benzoyl peroxide, abx, retinoids * oral - anti androgens abx, retinoids (severe) Generally treatment takes 6 weeks to take effect
31
What is prognosis of Malignant melanoma based on?
Breslow thickness 5 year survival based on TNM
32
What is impetigo
contagious superficial bacterial infection by staph aureus
33
what is this
Herpes simplex virus
34
Acne presentation
commonly affects face, chest and upper back * mild - non inflam lesions, open (black) and closed (white) comedones * mod/severe - papules, pustules, nodules and cysts
35
examples of derm fungal infections and their presentations
ring worm/tinea corporis: itchy circular or annular lesions. clearly defined, raised, scaly edge. Edge more inflammed than centre Yeast: itchy/irritation in affected area, white plaques on mucousal areas. Erythema with satellite lesions in flexures
36
pityriasis rosea management
self limting - will resolve in 2-12 weeks
37
How to assess a ?malignant melanoma
**ABCDE Symptoms** **A**symmetrical shape **B**order irregularity **C**olour irregularity **D**iameter \>6mm **E**voluation of lesion **Symptoms** bleeding, itching
38
Presentation of psoriasis
well demarcated erythematous scaley plaques can be itchy, burning or painful extensors nail changes - pitting, onycholysis (splits from nail bed)
39
What is psoriasis
chronic inflammatory skin disease due to hyperproliferation of keratinocytes and inflammatory cell infiltration
40
how does chickenpox present
red itchy lesions that turn into vesicles which crust to form scabs starts on face, scalp or trunk
41
what is scabies
where mites lay eggs in the skin causing intense itching especially at night
42
Presentation and management of pityriasis versicolor
multiple hypo pigmented scaly macules on upper trunk and back imidazole cream, ketoconazole shampoo
43
SCC management
* surgical removal * mohs micrographic surgery * radiotherapy - large non resectable tumours *
44
Management of BCC
surgical removal+ histology mohs micrographic surgery radio cyro, curettage, cautery for small low risk lesions
45
Management of lichen planus
topical steriods anti-histamines ±topical anti-fungals
46
Management of fungal infection
establish correct dignosis - skin scraping, hair/nail sample topical anti-fungals - terbinafine or imidazole oral antifungals - itraconazole
47
How does lichen planus present
Purple pruritic papules Symmetrical commonly on forearms, wrists, legs White lacey markings surrounding (wickhams striae)
48
which virus causes chicken pox/shingles
varicella zoster virus
49
Eczema management
avoid exacerbating agents emollients soap subs topical steriods for flare ups anti-histamines
50
Impetigo presentation
well defined lesoins with honey coloured crusts on erythematous base, starts around nose and face
51
eczema causes
genetic defect in skin barrier function exacerbating factors - infection, allergies, sweating, heat, stress
52
What is acne
inflammatory disease of pilosebaceous follicle
53
What is urticaria?
histamine driven inflammatory reaction Type 1 hypersensitivity reaction
54
what is this
Herald patch pitryiasis rosea
55
Management of chicken pox
self limiting paracetamol, calamine lotion aciclovir if severe
56
How does pityriasis rosea present?
Herald patch - oval red, scaly followed by other lesions in christmas tree distribution affecting neck and trunk
57
how does scabies present?
* linear burrows or rubbery nodules * pruritis worse at night * commonly in finger webs, sides of finers, wrists, elbows, ankles, feet, nipples, genitals * contact with symptomatic person?
58
Management of malignant melanoma
surgical excision radiotherapy chemo for met disease
59
urticaria managemetn
anti-histamines corticosteriods if severe
60
Management psoriasis
avoid precipitating factors emollients topical - vit D analogues, corticosteriods, coal tar preparations phototherapy oral for very severe - methotrexate, retinoids, ciclosporin
61
how long is chickenpox infective for?
4 days before rash starts and until all lesions have scabbed (around 5 days)
62
describe atopic eczema, and when its epidemiology
papules and vesicles on an erythematous base usually develops in childhood and resolves during teens
63
what is this
eczema
64
what is pityriasis rosea?
self limiting rash of unknown cause ?viral
65
how does BBC present?
Most commonly on head/neck Nodular most common type -small skin coloured papule/nodule with surface telangiectasia and pearly rolled edge. May have necrotic or ulcerated centre other types: superficial, cystic, morphoeic, keratotic

phase 3b (15 decks)

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