Public Health🥱 Flashcards
What is a case-control study?
A retrospective and observational study used to determine if there is an association between an exposure and a specific health outcome
What are the advantages of case-control studies? (2)
Good for rare outcomes
Quicker than cohort or intervention studies
Can investigate multiple exposures
What are the disadvantages of case-control studies? (3)
Difficulties finding controls to match with cases
Prone to selection and information bias
Cannot determine causality
Not good for rare exposures
What is a cohort study?
An epidemiological study where a group of individuals with a particular characteristic are followed up over time
What are the advantages of a cohort study? (2)
Can follow up a group with a rare exposure Good for common outcomes Can investigate multiple outcomes Less risk of selection and recall bias
What are the disadvantages of a cohort study? (2)
Takes a long time
Loss to follow up
Need a large sample size
What is a cross-sectional study?
An observational study that analyses data from a specific population at one point in time (snapshot)
What are the advantages of a cross-sectional study? (3)
Relatively cheap and quick
Provide data on prevalence at a single point in time
Large sample size
Good for surveillance and public health planning
What are the disadvantages of a cross-sectional study? (3)
Risk of reverse causality (did the exposure or outcome come first?)
Cannot measure incidence
Risk recall bias and non-response
What is a randomised controlled trial?
Subjects are randomly assigned to one of two groups - one receiving the intervention that is being tested, and one receiving an alternative (conventional) intervention
What are the advantages of a RCT? (2)
Low risk of bias and confounding
Can infer causality
What are the disadvantages of a RCT? (3)
Time consuming
Expensive
Specific inclusion/exclusion criteria may mean the study population is different from typical patients
Drop outs
What is selection bias?
A systematic error in the selection of study participants and allocation of participants to different study groups
E.g. Health studies that recruit participants directly from clinics miss all the cases who don’t attend those clinics or seek care during the study
Why does selection bias occur? (2)
Non-response
Loss to follow up
Those in an intervention group might be different in some way to those in the control group
What types of information bias are there?
Measurement bias
Observer bias
Recall bias
Reporting bias
What is measurement bias?
Different equipment used to measure the outcome in the different groups
What is observer bias?
Observers expectations influence reporting
What is recall bias?
Past events not recalled correctly
What is reporting bias?
Respondants report inaccurate information because they are embarassed or feel judged
What is confounding?
A situation in which the estimate between an exposure and an outcome is distorted because of the association with another factor that is also independently associated with the outcome
What is reverse causality?
A situation when an association between an exposure and an outcome could be due to the outcome causing the exposure
What factors increase the likelihood of causality? (3)
Strength of association
Consistency of results
Dose-response association
Plausibility
Reversibility
Coherence with other information
What is the purpose of screening?
Identifying apparently well individuals who have a particular disease in order to reduce adverse outcomes
What are the disadvantages of screening? (2)
Exposure of well individuals to distressing or harmful diagnostic tests Detection and treatment of sub-clinical disease that would never have caused any problems Preventative interventions that may cause harm to the individual or population
What is sensitivity?
The proportion of those with the disease who are correctly identified by the screening programme
What is specificity?
The proportion of people without the disease who are correctly excluded by the screening programme
What is the positive predictive value?
Proportion of people with a positive test result who actually have the disease
What is the negative predictive value?
Proportion of people with a negative test result who do not have the disease
What criteria emphasises the important features of screen programmes?
The Wilson and Jungner criteria
What are the 4 domains of the Wilson and Jungner criteria?
Knowledge of disease
The screening test
Treatment
Organisation and cost
List 5 points detailed in the Wilson and Jungner criteria.
In Exam Season NAP
I- important disease
E- effective treatment available
S- simple, safe and precise test
N- natural hx of disease known
A- acceptable to population (not too invasive)
P- policy on who to tx agreed
What are the 3 approaches to health needs assessment?
Epidemiological approach
Corporate approach
Comparative approach
What is an epidemiological approach to health needs assessment?
An approach to health needs assessment based on:
- size of population (incidence and prevalence)
- services available (prevention/treatment/care)
- evidence base (effectiveness/cost effectiveness)
Sources: disease registry, admissions, gp databases
What are the advanatages of an epidemiological approach? (2)
Uses existing data
Provides data on disease incidence/mortality and morbidity
Can evaluate services by trends over time
What are the disadvantages of an epidemiological approach? (2)
Quality of data variable
Data collected may not be the data required
Does not consider the felt needs or opinions/experiences of the people affected
What is a corporate approach to health needs assessment?
An approach to health needs assessment that asks the local population and a wide range of stakeholders what their health needs are - through focus groups, interviews and public meeting
What are the advantages of a corporate approach? (2)
Based on the felt and expressed needs of the population in question
Recognises the detailed knowledge and experience of those working with the population
Takes into account a wide range of views
What are the disadvantages of a corporate approach? (2)
Difficult to distinguish need from demand
Groups may have vested interests
May be influenced by political agendas
What is a comparative approach to health needs assessment?
An approach to health needs assessment that compares the health or healthcare provision of one population to another
What are the advantages of a comparative approach?
Quick and cheap if data is available
Indicates whether health or services provision is better/worse than comparable areas
What are the disadvantages of a comparative approach? (2)
May be difficult to find a comparable population
Data may not be high quality
May not yield what the most appropriate level of provision should be
What is equity?
Giving people what they need to achieve equal outcomes