Puberty

Question 1

Default phenotype in utero is
Due to what

Answer 1

Female

Question 2

What make a male be a male

Answer 2

SRY gene
Testosterone predominates wolffish duct formation
MIS muller Ian inhibiting g hormone secreted by Sertoli cells

Question 3

MIS
Mullerian inhibiting hormone is secreted by

Answer 3

Sertoli cells

Question 4

Male development chronologically

Answer 4

Testis —- scrotum —— penis—— pubic hair

Question 5

Female development

Answer 5

Increase in growth velocity —— breast development thelarche ——- pubic hair adrenarche. —- axillary hair —— menarche

Question 6

Breast development in females is due to what

Answer 6

Is due to ovarian estrogens

Question 7

Pubic hair growth in females is due to

Answer 7

Adrenal and ovarian androgens

Question 8

Age of menarche in African , western

Answer 8

12.3
12.8

Question 9

Seminefrous tubules are solid till what age

Answer 9

Till the age of 5 years

Question 10

Growth spurt occur due to 2 hormones

Answer 10

Gh
Igf1

Question 11

Estrogen is imp in puberty for

Answer 11

Epiphyseal fusion

Question 12

Bone mineralization in females is at the age of
And in male ?

Answer 12

In females 14-16 years
In males 17.5 years

Question 13

Puberty occur first in males or in female

Answer 13

It occurs first in female then after 2 years occur in males

Question 14

Describe GNrH changes in puberty

Answer 14

Increased GNrH pulsatilla secretion rhythm each 90-120 mins
Increased frequency of secretion leading to LH: FSh ration increasing

Question 15

Increased LH : FSH ration is a characteristic of which part of the cycle

Answer 15

Mid cycle

Question 16

Describe the pattern of FSH and LH secretion

Answer 16

Increasing levels of fsh and LH and peak at mid gestation then declines until term
GNrH increases in fetus till mid gestation

Question 17

Describe the fsh and LH levels from 2-9 years period of age

Answer 17

Low , juvenile paause

Question 18

Peripubertal description of gonadtophins and GNrH secretion

Answer 18

Gonadotrophin circadian ryhthem but only if estrogen present
GNrH secretion amplitude and frequency increases during early sleep .

Question 19

At early puberty when does the peak of fsh and LH occur

Answer 19

During the day .