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Endocrine Revision Notes > Hyppthalamic Hormones > Flashcards

Hyppthalamic Hormones Flashcards

1
Q

Paraventriculer nucleus site
Within th BBb or outside

A

Adjacent of the 3rd ventricle
Within the BbB

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2
Q

Paraventriculer nucleus have to types of neurons

A

Magnocelluler ADH and oxytocin
Parvocelluler ADH TRH CRh

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3
Q

Paraventriculer nucleus hormones

A

CRH
TRH

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4
Q

Arcuate nucleus

A

Dopamine and GHRH

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5
Q

Preoptic nucleus

A

GRH

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6
Q

Periventrinculer nucleus

A

Somatostatins

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7
Q

Supraoptic and Paraventriculer

A

ADh and oxytocin ‘
ADh supraoptic parvo and mango
Oxytocin Paraventriculer parvocelluer ,

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8
Q

Define dopamine

A

Prolactin inhibiting hormone

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9
Q

How many receptors does dopamine have

A

5 receptors

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10
Q

Dopamine is produced in 3 sites

A

Substantia nigra
Arcuate nucleus
Medulla of the adrenal glands

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11
Q

Mention 5 functions for dopamine

A

1 ) have a role in behavior , cognition , voluntary movements
2) inhibits prolactin
3 inotropic
4 chronotropic ‘5bstimulate comiiting via chemoreceptors trigger zone

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12
Q

What’s metoclopromide

A

Is dopaminergic receptor antagonist

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13
Q

Can dopamine cross the BBB

A

It’s can’t cross the BBB .

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14
Q

Dopamine is metablized by

A

COMT
mAo

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15
Q

GNrH is secreted by which nucleus

A

Preoptic nucleus

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16
Q

GNrH secretion pattern

A

Pulsation manner

17
Q

When is GNrH secretion pattern is pulstile frequency high and when is low

A

High in the follicular phase
Low in the late luteal phase

18
Q

Half life of GNrH

A

2-4 mins

19
Q

GNrH gene present on which chromosome

A

On chromosome 8

20
Q

Relation between GNrH , insulin and prolactin

A

Insulin increases GNrH activity
Prolactin decreases GNrH activity .

21
Q

Activity of the GNrH in th childhood

A

Is low

22
Q

Describe somatostatin اكتر اشي بميزه

A

Somatostatin is GHRH inhibitor
And inhibit TSH as well .

23
Q

Somatostain is secreted by

A

Intestine
Stomach
Pancreatic cells D cells
Thyroid cell parafolliculer cell s
Periventriculer cells

24
Q

What does somatostatin inhibits

A

1 GH
2 tsh
3 gastric emptying intestinal motility
Suppresses release of pancreatic hormone
Inhibits
Gastrin
Cck
Motility
Secretin
Insulin
Glucagon
VIP vasoactive intestinal peptide .

25
Q

TRH released from
And stimulate release of

A

From the Paraventriculer nucleus
Secret the release of TSH , prolactin

26
Q

Melatonin is derived from

A

Serotonin

27
Q

Describe the activity of melatonin

A

Bio rhythmic and diurnal

28
Q

What increase release of the melatonin

A

Darkness
Hypoglycemia

29
Q

Sites of melatonin production

A

👁️ retina , lens of the eye 👁️ , GIT , pineal gland , suprachiasmatic nucleus .

30
Q

Gonadotrophins and melatonin relation

A

Melatonin inhibits gonadotrophins .

Endocrine Revision Notes (4 decks)

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