PSYCHOTROPIC MEDS Flashcards
antipsychotics: target symptoms
positive symptoms; agitation, hallucinations, delusions, combativeness/belligerent behavior, sleep disturbance, tension, paranoid behavior/disorganized thinking
antipsychotics: symptoms less likely to respond
negative symptoms; impaired judgement, lack of insight, depression and withdrawal, poor motivation
antipsychotics: side effects
sedation, postural hypotension, weight gain, photosensitivity, sexual dysfunction, breast swelling, anticholinergic (dry mouth, blurred vision, urinary hesitation, constipation), tardive dyskinesia, acute dystonic reactions (involuntary muscle spasms or tightening of face), neuroleptic malignant syndrome (medical emergency, fever, muscle rigidity, mental status changes)
antipsychotics: tardive dyskinesia side effect treat
limit antipsychotic exposure, use vitamin E for prevention
antipsychotics: extrapyramidal symptoms (parkinsonian movements) treat
Artane, Cogentin, benadryl
antipsychotics: common atypical; clozapine
clozaril
different action
side effects–high saliva production, sedation, nausea, hypotension, dizziness, weight gain, risk of seizures; no tardive dyskinesia
need for weekly blood monitoring
antipsychotics: common atypical; resperidone
riserdal
injectable
side effects; sedation, some headache, dry mouth, constipation, blurred vision, palpitations, no tardive dyskinesia
question of relief for positive and negativesymptoms
antipsychotics: newer meds
apriprazole--abilify ziprasidone--geodon quetiapine--seroquel olanzapine--zyprexa asenapine-saphris paliperidone palmitate--invega sustenna paliperidone-invega illoperidone--fanapt
tricyclic antidepressants: side effects
autonomic, anticholinergic (dry mouth, blurred vision, constipation, urinary probs, sweating/heat sensitivity), pustural hypotension, tachycardia, change in EKG arhythmias
tricyclic antidepressants: contraindicated for
people with heart disease, lethal in high doses so not good for suicidal pts
tricyclic antidepressants: therapeutic effects in
2-3 weeks
monoamine oxidase inhibitors (MAOIs): most effective for
atypical and nonendogenous depression
monoamine oxidase inhibitors (MAOIs): side effects
hypertension with high dose or when tricyclic/stimulant also taken
monoamine oxidase inhibitors (MAOIs): adverse drug reactions
stimulants, appetite suppressants, cold remedies, cocaine derivatives, anything that raises blood pressure
monoamine oxidase inhibitors (MAOIs): dietary restrictions
food with high levels of tyramine; avoid beer/ale, wine, cheese, smoke/pickled fish, beef/chicken liver, summer sausage, italian beans, yeast vitamin supplements
second generation antidepressants: benefits
reduced, different side/averse effects
second generation antidepressants: SSRIs therapeutic efficacy similar to
TCAs (tricyclic acids)
second generation antidepressants: SSRIs side effects are dose related
weight loss, nausea, diarrhea, nervousness (fluoxetine/prozac), insomnia, sexual dysfunction with long term use, less toxic to heart and safer in overdose than TCAs
second generation antidepressants: SNRIS side effects dose related
dry mouth, loss of appetite, nausea, diarrhea, constipation, nervousness, insomnia, elevated blood pressure and sexual problems
less toxic and safer in overdose
mood stabilizers: lithium
narrow therapeutic index; need blood levels/kidney/thyroid checked regularly
mood stabilizers: lithium side effects
thyroid can enlarge and underactive (treat with thyroid replacement meds)
renal kidney impact, need to drink more water for dehydration
gastrointestinal (anorexia, cramps, nausea, vomiting)
CNS (mental dullness, decreased memory and concentration, headache, hand tremors, fatigue and lethargy, weight gain)
mood stabilizers: lithium; don’t take
during first trimester of pregnancy
mood stabilizers: sometimes combined
with antidepressant or antipsychotic
mood stabilizers: therapeutic effect
2+ weeks to build dosage to therapeutic level, need LI does multiple times a day