Psychotic Disorders Flashcards

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1
Q

Define psychosis

A
  • delusions
  • hallucinations
  • disorganized though/ behavior

*It is a SYMPTOM of many different conditions

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2
Q

Two types of delusions

A

bizarre vs nonbizarre

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3
Q

Define somatic delusions

A

belief that one has a disease/ illness

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4
Q

Visual hallucination causes

A
  • drug intox
  • delirium
  • drug and alcohol withdraw
  • lewey body
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5
Q

Most common causes of tactile hallucinations

A

-secondary to drug use or alcoholic withdraw

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6
Q

Endocrine related causes of psychosis

A
  • hypo/hyperthyroid
  • hyper/hypocalcemia
  • hypopituitarism
  • cushings
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7
Q

Three vitamin related causes of psychosis

A
  • B12
  • folate
  • niacin
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8
Q

Three random disease states assc with psychosis

A
  • SLE
  • porphyria
  • temporal arteritis
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9
Q

Criteria common to psychosis induced by either medical condition or medication

A
  • symptoms do not only occur during delirium

- not better accounted for by a psych disorder

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10
Q

Length of time required for diagnosis of:

  • schizophrenia
  • schizophreniform
  • brief psychotic disorder
A

schizo six months
schizophreniform 1-6 mos
brief less than month

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11
Q

Important workup when schizophrenia is expected

A

TSH
RPR
brain imaging

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12
Q

Three categories of schizo symptoms

A
  • positive
  • negative
  • cognitive
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13
Q

Three phases of schizophrenia

A
  • prodromal
  • psychotic
  • residual
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14
Q

What are the five A’s/negative symptoms of schizophrenia?

A
  • anhedonia
  • affect
  • alogia
  • avolition
  • attention
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15
Q

Symptomatic criteria for schizo

A

must have 3 symptoms, one of which must be a positive symptom (hallucination, delusion, disorganized speech)

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16
Q

Births in what time of year increase risk of schizophrenia?

A

-late winter and early spring

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17
Q

Age period during which schizophrenia presents

A

15-55

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18
Q

Contrast males and females with schizo

A

men earlier, more negative symptoms, poorer prognosis

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19
Q

Define downward drift

A

-schizo prevalent in low SES because patients fail to succeed in careers

20
Q

Two pathways involved in schizophrenia

A
  • mesolimbic: high dopa = positive symptoms

- prefrontal/mesocortical: low dopa= negative symptoms

21
Q

Lifetime prevalence of schizophrenia

A

1%

22
Q

Five NT changes in schizo

A

-high serotonin and NE
-low GABA, glutamate receptors (NMDA)
(major= high dopa)

23
Q

How is ketamine related to schizophrenia?

A
  • schizo= low NMDA receptors

- ketamine blocks NMDA receptors

24
Q

CT changes in schizophrenia

A
  • large ventricles

- cortical atrophy

25
Q

Good prognostic features in schizophrenia

A
  • late acute onset
  • positive symptoms
  • female
  • few relapses, good premorbid function
26
Q

MOA first gen antipsychotics

A

D2 antagonists

27
Q

MOA atypicals

A

antagonist 5HT and D4 more than D2 receptors

28
Q

Contrast ADRs of typical vs atypical antipsychotics

A
  • typical: risk extrapyramidal effects

- atypical: risk metabolic effects

29
Q

How long until antipsychotics are effective?

A

1 month

30
Q

List four typical antipsychotics

A
  • haloperidol
  • fluphenazine
  • perphenazine
  • chlorpromazine
31
Q

What population most commonly suffers from tardive dyskinesia?

A

-older women 6 months after beginning treatment

32
Q

Treatment for extrapyramidal side effects

A
  • anticholinergics
  • BDZs
  • BBers
33
Q

Two weight neutral atypicals

A
  • aripiprazole

- ziprasidone

34
Q

Treatment of tardive dyskinesia

A

BDZ
Botox
Vitamin E

35
Q

Two antipsychotics that effect the eye

A
  • thioridazine: retinal pigmentation

- chlorpromazine: deposits in lens and cornea

36
Q

How many patients recover from schizophreniform disorder?

A

1/3

37
Q

Schizoaffective disorder

A
  • Meet criteria for major depressive/ manic episode + schizophrenia symptoms
  • delusions/hallucinations present for 2 weeks without mood symptoms
38
Q

Contrast schizoaffective d/o & mood d/o + psychotic features:

A

-mood disorder= no psychosis in absence of mood episode

39
Q

What may trigger brief psychotic disorder

A

extreme stress

40
Q

Delusional d/o criteria

A
  • delusions for at least one month do not meet criteria for schizophrenia
  • usually nonbizarre and can function in society
41
Q

Define erotomaniac delusions

A

another person is in love with them

42
Q

Treatment for delusional disorder

A

antipsychotics

43
Q

Psychotic disorder in southeast asia

A

Koro (penis will recede into body)

44
Q

Psychotic disorder in Malaysia

A

Amok (violence –> suicide)

45
Q

Describe schizotypal personality disorder

A

paranoid, odd, magical beliefs

lack of friends

46
Q

Describe schizoid personality disorder

A

lack of enjoyment from socialization