Psychotic Disorders Flashcards

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1
Q

Presents in 20’s often after life stressor, thought process disorder, thought to be due to overload of dopamine and serotonin.

A

Schizophrenia

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2
Q

Positive Symptoms of Schizophrenia

A

Bizarre Delusions
Hallucinations
Disorganized Speech
Disorganized or Catatonic Behaivor

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3
Q

Negative Symptoms of Schizophrenia

A

Flat Affect
Cognitive Defects
Poverty of speech anhedonia

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4
Q

Treatment for schizophrenia

A

First gen antipsychotics like haloperidol, fluphenazine, thioridazine, chlorpromazine

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5
Q

What leads to the negative symptoms in schizophrenia?

A

Decreased dopamineric activity inthe mesolimbic pathwayWh

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6
Q

What leads to positive symptoms in schizophrenia?

A

Increased dopaminergic activity in the mesolimbic pathway

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7
Q

What leads to extrapyramidal symptoms in the use of antipscychotics

A

Antipsychotics particuarly first gen make a dopamine blockage all across the board so it will block dopamine in the nigrostriatal tract that could result in parkinsonism/EPS

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8
Q

How do you get gynecomastia and galactorrhea?

A

Blockade of dopamine in the tuboinfundibular tract (disinhibtion of prolactin!)

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9
Q

What is the criteria for a breif psychotic disorder?

A

Severe stressor–> psychotic features onset of greater than a day with duration less than a month

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10
Q

What is the timeline for schizophreniform?

A

duration is 1-6 months

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11
Q

How might we differentiate between schizophrenia and schizoaffective?

A

Schizoaffective is where we see the mood symptoms predominate. No mood symptoms at all means its schizophrenia.

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12
Q

Which disorder: lasts greater than a day and less than a month and exhibits psychotic symptoms

A

Breif Psychotic Disorder, this can PROGRESS to schizophreniform

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13
Q

Which Disorder: lasts greater than a month and less than six months

A

Schizophreniform

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14
Q

Psychotic features lasting greater than 6 months without mood disorder

A

schizophrenia

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15
Q

Psychotic features wtih mood like major depressive episode and mania

A

Schizoaffective

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16
Q

What medications are used to treat POSITIVE symptoms?

A

Haloperidol, thiazide, chlorpromazine

17
Q

What medications are used to treat NEGATIVE symptoms?

A

Risperidone, quetipine, olanzapine, ziprasidone, ariprprazole

18
Q

Things are happening around us but we feel as though they are not happening to us

A

Dissociation

19
Q

How do we treat dissociative identity disorder?

A

intense psychotherapy to align the personalities into one, hypnosis

20
Q

How may dissociative identity arise?

A

Different identities/personalities arise as a means of protecting the self

21
Q

Inability to recall or inconsistency in recall often associated with acute emotionall traums or stressor

A

Discciative amnesia

22
Q

If there is travel involved in dossociative amnesia, what do we refer to it as?

A

Dissciative fugue

23
Q

Catatonia is defined by at least three of the following…

A

stupor, catalepsy, waxy flexibility, mutism, negativism, stereotypy, agitation, echolalia, echopraxia

24
Q

How do we treat catatonia?

A

Lorazepam, food/nutrition support, watch for risk of dvt and rhabdo

25
Q

How do we treat refracrory catatonia?

A

ECT

26
Q

Immobility, fever, elevated CK, autonomic instability are consistent with

A

Malignant catatonia, neuroleptic catatonia syndrome, serotonin catatonia, malignant hyperthermia

27
Q

Malignant catatonia is caused by…

A

Non drug induced! Immobility/rigidity, fever, elevated CK

28
Q

Neuroleptic catatonia syndrome is caused by…

A

antipsychotics, presents the same as malignant catatonia but is caused by the drugs

29
Q

How can you differentiate serotonin syndrome from malignant catatonia and NMS?

A

SS presents with leadpipe rigidity (myoclonus and hyperreflexia) and hx/current ssri use

30
Q

What drug leads to malignant hyperthermia?

A

Halothane

31
Q

How do we treat malignant hyperthermia?

A

Dantrolene

32
Q

Characerized by psychotic sx’s (delusions, hallucinations, disorganization, negative sx’s) along with significant mood episodes (MDD, manic episodes). Sx’s must exceed 6 months

A

Schizoaffective disorder

33
Q

What is the timeline fro schizophreniform?

A

Demonstrating pyschoic features for greater than 1 months and less than 6 months. 2/3rds of patients ultimately develop schizophrenia

34
Q

How does schizopfreniform and schizophrenia impact other cognitive functions?

A

attention, working memory, verbal learning, memory, and executive function all are impacted