Psychotic Disorders Flashcards
Presents in 20’s often after life stressor, thought process disorder, thought to be due to overload of dopamine and serotonin.
Schizophrenia
Positive Symptoms of Schizophrenia
Bizarre Delusions
Hallucinations
Disorganized Speech
Disorganized or Catatonic Behaivor
Negative Symptoms of Schizophrenia
Flat Affect
Cognitive Defects
Poverty of speech anhedonia
Treatment for schizophrenia
First gen antipsychotics like haloperidol, fluphenazine, thioridazine, chlorpromazine
What leads to the negative symptoms in schizophrenia?
Decreased dopamineric activity inthe mesolimbic pathwayWh
What leads to positive symptoms in schizophrenia?
Increased dopaminergic activity in the mesolimbic pathway
What leads to extrapyramidal symptoms in the use of antipscychotics
Antipsychotics particuarly first gen make a dopamine blockage all across the board so it will block dopamine in the nigrostriatal tract that could result in parkinsonism/EPS
How do you get gynecomastia and galactorrhea?
Blockade of dopamine in the tuboinfundibular tract (disinhibtion of prolactin!)
What is the criteria for a breif psychotic disorder?
Severe stressor–> psychotic features onset of greater than a day with duration less than a month
What is the timeline for schizophreniform?
duration is 1-6 months
How might we differentiate between schizophrenia and schizoaffective?
Schizoaffective is where we see the mood symptoms predominate. No mood symptoms at all means its schizophrenia.
Which disorder: lasts greater than a day and less than a month and exhibits psychotic symptoms
Breif Psychotic Disorder, this can PROGRESS to schizophreniform
Which Disorder: lasts greater than a month and less than six months
Schizophreniform
Psychotic features lasting greater than 6 months without mood disorder
schizophrenia
Psychotic features wtih mood like major depressive episode and mania
Schizoaffective