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PSYCH SHELF > MOOD MEDS > Flashcards

MOOD MEDS Flashcards

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1
Q

What are the SSRIs?

A

Escitalopram
Citalopram
Fluoxetine
Paroxetine
Sertraline

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2
Q

What are the side effects for SSRIs?

A

Decreased libido, delayed ejaculation, serotonin syndrome, GI, insomnia

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3
Q

What are the signs of serotonin syndrome

A

Serotonin syndrome is a potentially life-threatening condition caused by serotonergic overactivity due to the use of serotonergic drugs. It can be caused by a therapeutic dose or overdose of a serotonergic drug, concomitant use of multiple serotonergic drugs, or interactions with CYP450 inhibitors. Onset is typically rapid, occurring within 24 hours of drug administration. Classic features include autonomic dysfunction, neuromuscular excitability (e.g., rigidity, hyperreflexia), and altered mental status. Increased neuromuscular activity can also lead to hyperthermia.

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4
Q

what are the signs of lithium toxicity

A

Acute lithium poisoning
Early: gastrointestinal symptoms
Hours after ingestion: neurological symptoms
Acute-on-chronic lithium poisoning: Gastrointestinal and neurological symptoms may occur simultaneously.
Chronic lithium poisoning: Neurological symptoms predominate.
Gastrointestinal: nausea, vomiting, and diarrhea
Neurological
Altered mental status, confusion
Somnolence, coma
Delirium, encephalopathy, psychomotor impairment
Coarse tremors, seizures, fasciculations, myoclonus
Ataxia, slurred speech, nystagmus
Hyperreflexia
Extrapyramidal syndrome

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5
Q

What labs/imaging must you start before starting an antipsychotic?

A

ECG!
And some require CBC, LFTs, or RFTs

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6
Q

SNRIs

A

Venlafaxine
Desvenlafaxine
Duloxetine

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7
Q

Atypical antidepressents

A

Buproprion

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8
Q

Serotonin modulators

A

Mirtazapine and trazodone

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9
Q

What is mirtazapine?

A

Appetite stim

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10
Q

What are the TCAs?

A

Things that end in ‘tryptilline’
Imipramine
Desipramine
Doxepin

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11
Q

What major side effects can you have with TCAs?

A

Enuresis, convulison/coma/cardiac, anti-ach including dry mouth, sedation, urinary retention, constipation

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12
Q

What studies must you order before starting TCAs?

A

ECG because it can widen the QRS leading to arrythmias

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13
Q

What are anticholinergi side effects and what meds are they associated with?

A

Anticholnergic include dry mouth/dry eyes, dialated pupils, urine retention, constipation

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14
Q

Whats in a B52?

A

haloperidol, lorazepam, and diphenhydramine

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15
Q

What is first line treatment for GAD, OCD, and PTSD?

A

~therapy~

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16
Q

Firstline drug of choice for bipolar 1

A

Lithium

17
Q

Drug next in line for bipolar if lithium is contraindicated

A

Valproate

18
Q

Major side effects for lithium

A

Its a teratogen, neprhotoxic kidney injury 1.5 cr and obove, can cause nephrogenic diabetes, has a narrow therapeutic index, can lead to hypothyroidism

19
Q

Side effects of valproate

A

teratogen (spina bidifa), thrombocytopenia, agranulocytosis, pancreatitis

20
Q

Second line medication for bipolar and can be used in all phases of treatment (in mania AND maintence)

A

quetiapine

21
Q

Quetiapine major side effects

A

weight gain and QTC prolongation

22
Q

Lamotrigine

A

mood stab, second line tx for bipolar, side effects include blurred vision and steven johnson

23
Q

Carbamazepine

A

thirdline mood stab for bipolar, can be used to help tx trigeminal neuralgia and absence seizures. Its a teratogen (cleft palate), rash, sjs, av block

24
Q

What do you use to tx bipolar in the acute phase/manic phase?

A

Li + antipsychotic

25
Q

What do you use to treat depressed mood in bipolar?

A

quetiapine

26
Q

major sign of nephrogenic diabetes insipidus

A

hypernatremia

27
Q

If a patient on lithium develops renal toxicity, what do you do?

A

Switch them to valproate

28
Q

If a patient has refractory Bipolar, what meds would you recommend?

A

Li or valproate plus an antipsychotic like quetiapine

29
Q

Major side effects of quetiapine

A

sedation and QTc prolongation weight gain

30
Q

Treatment of specific phobias consists of CBT or medications that target…

A

gamma aminobutyric acid type A receptors (GABA). Benzos modulate gaba.

31
Q

Benzodiazepines target what

A

GABA

32
Q

Phobias are treated with

A

BENZOS!

33
Q

Buspirone targets what

A

serotonin agonist

PSYCH SHELF (9 decks)

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