Psychotic Disorders Flashcards

An Exemplar of Schizophrenia

1
Q
  1. What is the most important causal factor in schizophrenia?
A

Biological factors, particularly genetic and neurobiological influences, are often considered crucial.

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2
Q

Can schizophrenia be inherited?

A

Yes, schizophrenia has a genetic component, and family history can increase the risk.

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3
Q

What are the most common delusions in schizophrenia?

A

Delusions of persecution, grandeur, or control are common.

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4
Q

What are positive symptoms in schizophrenia?

A

hallucinations, delusions, and disorganized speech or behavior.

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5
Q

What are negative symptoms in schizophrenia?

A

Negative symptoms involve diminished emotional expression, lack of motivation, and social withdrawal.

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6
Q

What are disorganized symptoms in schizophrenia?

A

Disorganized symptoms include erratic behavior, speech incoherence, and inappropriate emotional responses.

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7
Q

What is the prodromal phase of schizophrenia?

A

The prodromal phase is marked by early, vague symptoms like social withdrawal, unusual behavior, and changes in functioning.

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8
Q

What is the active phase of schizophrenia?

A

In the active phase, the most severe symptoms, including hallucinations, delusions, and disorganized speech, are present.

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9
Q

What is the residual phase of schizophrenia?

A

The residual phase follows the active phase, with symptoms reducing in intensity, but negative symptoms often remain.

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10
Q

What is the DSM-5 definition of psychosis?

A

Psychosis in the DSM-5 is defined by the presence of delusions, hallucinations, disorganized thinking, or grossly disorganized behavior.

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11
Q

What age range is most commonly affected by schizophrenia?

A

Schizophrenia often emerges in late adolescence or early adulthood, typically between ages 15 and 35.

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12
Q

What is the “attenuated psychosis disorder” (APD)?

A

APD refers to subclinical symptoms that may precede full-blown psychosis, but it was not adopted as a formal diagnosis in DSM-5.

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13
Q

What does it mean for someone to be in the “relapse” phase of schizophrenia?

A

The relapse phase involves the re-emergence of positive symptoms like hallucinations or delusions after a period of symptom remission.

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14
Q

What are hallucinations?

A

Hallucinations are sensory experiences, such as hearing voices or seeing things that aren’t present, and are a hallmark of psychotic disorders.

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15
Q

What is the duration requirement for schizophrenia diagnosis?

A

Symptoms must be present for at least 6 months, with at least 1 month of active phase symptoms.

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15
Q

What are delusions?

A

Delusions are false beliefs held with strong conviction despite evidence to the contrary, commonly seen in schizophrenia.

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16
Q

How is the diagnosis of schizophrenia made according to DSM-5?

A

A diagnosis is made if at least two of five key symptoms (delusions, hallucinations, disorganized speech, disorganized behavior, negative symptoms) are present, with at least one being delusions, hallucinations, or disorganized speech.

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16
Q

How do cultural factors influence the experience of mood disorders?

A

Cultural factors can affect stigma, symptom presentation, and the reporting of symptoms in mood disorders.

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17
Q

What is the role of biological markers in schizophrenia research?

A

Schizophrenia research aims to uncover biological markers to better understand its neurobiological basis, although definitive markers have yet to be established.

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18
Q

How does schizophrenia differ from other mental disorders in terms of recovery rates?

A

Schizophrenia tends to have lower recovery rates compared to other disorders, with less than 50% of patients recovering after 15-25 years.

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19
Q

What is the difference between internal and external stimuli in psychosis?

A

In psychosis, individuals have difficulty distinguishing between internally generated thoughts or sensations and external reality.

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19
Q

What are the three core symptom types in schizophrenia?

A

The three core symptom types are positive symptoms, negative symptoms, and disorganization.

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20
Q

What are the key indicators for diagnosing schizophrenia in the active phase?

A

delusions, hallucinations, and disorganized speech.

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20
Q

Why is schizophrenia considered a spectrum disorder?

A

due to the wide variability in symptom presentation and severity across individuals.

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20
Q

What is the “split from reality” in psychosis?

A

This refers to the inability of individuals to distinguish between what is real and what is not, a hallmark of psychosis.

21
Q

What is the role of medication in treating schizophrenia?

A

Medication, often antipsychotics, is a key component of treatment, aiming to reduce symptoms like delusions and hallucinations.

21
Q

What is the significance of the “timing, onset, and duration” in diagnosing schizophrenia?

A

These factors help determine the stage of the disorder and ensure that the symptoms meet the required duration for diagnosis.

21
Q

What is the impact of psychotic features on daily functioning?

A

Psychotic features like delusions and hallucinations significantly impair the individual’s ability to function in everyday life.

22
Q

What is the difference between the residual phase and the prodromal phase?

A

The prodromal phase involves early, vague symptoms before the onset of full psychosis, while the residual phase follows the active phase, with reduced but still impairing symptoms.

23
Q

What is catatonic behavior in schizophrenia?

A

Catatonic behavior includes abnormal motor behavior, such as rigidity, excessive movement, or lack of response to external stimuli.

24
Q

What are auditory hallucinations in schizophrenia?

A

They are voices (familiar or unfamiliar) distinct from one’s own thoughts, often unpleasant and uncontrollable, and may issue instructions, tease, or comment.

24
Q

What auditory events do not count as schizophrenia symptoms?

A

Hypnogogic hallucinations (falling asleep), hypnopompic hallucinations (waking up), hearing your name called, and sounds caused by external events like ringing in ears.

25
Q

What defines delusions in schizophrenia?

A

Delusions are false, unshakable beliefs that are preoccupying and held despite contradictory evidence, reflecting a disturbance in thought content.

26
Q

What are common delusional themes in schizophrenia?

A

Themes include being controlled, persecution, and grandeur, such as feelings of being harassed or having special powers.

27
Q

How do delusions vary culturally?

A

Beliefs may not be delusional if they are shared by a cultural group, but unusual beliefs within a socio-cultural context may be considered delusional.

28
Q

What is disorganized speech in schizophrenia?

A

Speech that doesn’t make sense, marked by derailment, loose associations, or alogia (poverty of speech), reflecting disorganized thinking.

28
Q

What is catatonia in schizophrenia?

A

Catatonia is marked by reduced reactivity, motoric immobility, or excessive purposeless movement, such as pacing, often disconnected from external cues.

28
Q

What makes delusions hard to identify?

A

They may involve complex or fragmented belief systems, blending facts and fiction, making them difficult to disprove or fully understand.

29
Q

How is disorganized behavior in schizophrenia diagnosed?

A

Behavior is considered disorganized if it’s bizarre or incongruent with the situation, beyond aimlessness or agitation, reflecting disturbed thought processes.

29
Q

What are examples of disorganized speech?

A

Examples include word salad, tangential speech, derailment, and poverty of content, where speech is fragmented or unrelated to questions asked.

30
Q

What is delusional disorder?

A

Delusional disorder involves delusions without the broader range of schizophrenia symptoms like hallucinations or disorganized speech.

31
Q

What are negative symptoms in schizophrenia?

A

Negative symptoms include diminished emotional expression, avolition (lack of motivation), and alogia, often more subtle and harder to recognize.

32
Q

What is brief psychotic disorder?

A

It is a short-term disorder marked by psychotic symptoms like delusions or hallucinations, typically lasting less than a month.

33
Q

Is the cause of schizophrenia known?

A

No, the cause of schizophrenia is not fully known, and it may not have a single cause due to the heterogeneity of the disorder.

33
Q

Why were schizophrenia subtypes removed in DSM-5?

A

The subtypes were removed due to poor reliability in distinguishing them, and they were replaced with specifiers for better classification.

34
Q

What is the importance of sociocultural factors in schizophrenia diagnosis?

A

Sociocultural factors play a crucial role in identifying and diagnosing schizophrenia, as cultural context influences symptom presentation and interpretation.

35
Q

What is the primary theory regarding the cause of schizophrenia?

A

The primary theory is biological, and many factors, including genetics, are implicated. The main treatments are pharmacological.

36
Q

What role do genetics play in schizophrenia?

A

Genetics contribute to the risk, but do not provide a complete explanation. The risk is higher for family members of those affected, though not all relatives will develop the disorder.

36
Q

What is the diathesis-stress model in schizophrenia?

A

This model suggests that genetic predisposition (diathesis) interacts with environmental stressors, such as family environment, to increase the risk of schizophrenia.

36
Q

How do prenatal factors influence the risk of schizophrenia?

A

Pregnancy complications, maternal viral infections, dietary deficiencies, and stress during pregnancy are thought to impact neurodevelopment and increase the risk.

36
Q

What are the gender differences in schizophrenia?

A

Schizophrenia is more common in males, who tend to have earlier onset, more chronic symptoms, and a preponderance of negative symptoms.

37
Q

What challenges exist in studying neuroanatomical changes in schizophrenia?

A

It’s difficult to determine whether changes in brain structure and function are due to the illness itself, the effects of medication, or the experience of living with schizophrenia over time.

37
Q

What is the dopamine hypothesis in schizophrenia?

A

The dopamine hypothesis suggests that schizophrenia may involve abnormal dopamine activity, but it may be too narrow an explanation, as other neurotransmitters like glutamate also seem to play a role.

38
Q

How might substance use influence the development of schizophrenia?

A

Early cannabis exposure and high substance use may increase the risk of psychosis, particularly in adolescents at clinical high risk for psychosis.

39
Q

How do psychological interventions help people with schizophrenia?

A

Psychological interventions, like family-based therapies, physical activity, and social skills training, can be useful, especially for those stabilized on medication.

40
Q

What is the role of family environment in the development of schizophrenia?

A

High expressed emotion in family environments, such as criticism and overinvolvement, has been associated with increased risk and worse outcomes in schizophrenia.

41
Q

What is the relationship between psychotic-like experiences (PLEs) and schizophrenia?

A

PLEs are not the same as psychosis but may indicate a risk for developing psychosis, particularly in young people with high substance use.

42
Q

What is the primary treatment for schizophrenia?

A

The primary treatment is antipsychotic medication, which works by blocking D2 dopamine receptors, but there are challenges such as side effects, poor compliance, and tolerance.

43
Q

What is the diathesis-stress model’s role in explaining schizophrenia?

A

It provides a promising explanation, recognizing both biological vulnerabilities and environmental stressors as contributing factors to the development of schizophrenia.

44
Q

What is the prognosis for people with schizophrenia?

A

Prognosis varies, with fewer than 25% recovering fully. Long-term treatment is often required, and outcomes depend on factors like gender, with males having a worse prognosis.