Psychotherapeutic Agents Flashcards
Drug names for Antipsychotic / Neuroleptic Drugs
(Psychotherapeutic Agents) Typical Antipsychotics:
-azine
prochlorperazine
thioridazine
chlorpromazine
-Haloperidol
Drug names for Antipsychotic / Neuroleptic Drugs
(Psychotherapeutic Agents) Atypical Antipsychotics:
-apine
quetsapine
olanzapine
clozapine
-idone
risperidone
ziprasidone
Actions of Antipsychotic / Neuroleptic Drug?
- typical antipsychotic drugs block dopamine receptors, preventing the stimulation of post synaptic neurons by dopamine
- depress the RAS limiting stimuli coming into the brain
Atypical antipsychotic block both dopamine & serotonin
Indication?
why would I use Antipsychotic / Neuroleptic Drug?
Schizophrenia, hyperactivity, combative & agitated behavior severe behavioral problem in children
Adverse effects for Antipsychotic / Neuroleptic Drug
CNS: drowsy/sedation weakness tremors extrapyramidal effects -pseudoparkinsonsim -dystonia (spasm) -akathisia (restlessness) -tardive dyskinesia (smacking lips) -neuroleptic malignant syndrome (increased fever, muscle rigidity, change in BP, can be fatal) Anticholinergic: constipation, dry mouth, nasal congestion
Contraindications for Antipsychotic / Neuroleptic Drug
allergy/ hypersensitivity CNS depression blood dycrasias parkinsons prolonged QT interval (CAD)
Caution for Antipsychotic / Neuroleptic Drug
conditions that would worsen by anticholinergic effects
liver, renal, cardiac disease
drug/ drug for Antipsychotic / Neuroleptic Drug
beta blockers
alcohol
anticholinergics
Assessment for Antipsychotic / Neuroleptic Drug
blood glucose, cautions/ contraindications, CAD, VS
CNS
Labs:
renal, hepatic, CBC
Implementation for Antipsychotic / Neuroleptic Drug
parenteral form: recumbent (lay down) for 30 min monitor CBC arrange for gradual dose reduction after long term use provide positioning of arms/legs provide sugarless candy & ice chips encourage pt to void before dose safety measures vision examinations
evaluation for Antipsychotic / Neuroleptic Drug
Response to drug: decrease s/sx of psychotic disorder
ADE:
producing milk when you are not a new mom
Growing breast tissue in males
pharmacokinetics for Antipsychotic / Neuroleptic Drug
IM dose provided 4-5 times the active dose as oral dose
Drug Names for Bipolar disorder:
Lithium
Action for Bipolar disorder:
- Unknown
- Alter sodium transport in nerve and muscle cells
- Influences the reuptake of neurotransmitters (norepinephrine/dopamine)
Indications for Bipolar disorder:
Bipolar disorder