Anti Protozoal Agents Flashcards
Drug Names for Antimalarials
antiprotozoal agents
-quin Quinine Chloroquine Mefloquine Primaquine
Action for Antimalarials
antiprotozoal agents
Enter human RBC and changes metabolic pathways necessary for reproduction of Plasmodium
Indication for Antimalarials
antiprotozoal agents
Prevent acute malarial reaction in individuals who have been infected by the parasite, or work against tissue schizonts as prophylactic or antiriepase agents
Adverse effects for Antimalarials
antiprotozoal agents
CNS GI Hepatic dysfx Dermatological Blindness Ototoxicity
Contraindication for Antimalarials
antiprotozoal agents
Allergy
Liver disease
Alcoholism
P/L
Cautions for antimalarials
antiprotozoal agents
- Retianl disease or damage
- psoricisis or porphyria
- damage to mucous membranes
Drug/ drug for Antimalarials
antiprotozoal agents
- Pt receiving quinine derivative and quinine are at high risk for cardiac toxicity and convulsions
- anti folate drugs increase bone marrow suppression
Nursing Diagnosis for Antimalarials
antiprotozoal agents
acute pain r/t GI, CNS and skin effects
disturbed sensory perception r/t CNS
Risk for injury r/t CNS
deficient knowledge
Assessment for Antimalarials
antiprotozoal agents
cautions/ contraindications CNS optalmic/ retinal exams auditory screening inspect skin blood culture
Implementation for Antimalarials
antiprotozoal agents
C/S test before full course of drug mark calendar for prophylactic dose hepatic fx and opthalmic exam before and during therapy safety- CNS small nutritious meals- sever GI upset
evaluation for Antimalarials
antiprotozoal agents
drug response:
resolution of malaria or prevention
ADE: CNS, nutritional state skin color or lesions hepatic fx visual & auditory changes
Other protozoal infections
antiprotozoal agents
Amebiasis Leishmaniasis Trypasomiasis Trichmoniasis Giardiasis Pnemocystic jiroveci pneumonia (PCP)
Drug Names for Other protozoal infections
antiprotozoal agents
Atovaquone Metronizadole Pentamide Tinidazole Benznidazole 9
Action for Other protozoal infections
antiprotozoal agents
inhibits DNA synthesis in susceptible protozoal
Indication for Other protozoal infections
antiprotozoal agents
Atovaquone: especially active against PCP Metronizadole: treats amebiasis, trichomoniasis, giardisis Pentamide: PCP, trypanosomiasis, leishmaniasis Tinidazole: tricho, giardiasis, amebiasis Benznidazole 9: ped. patient with chagas