Psychostimulants and substance abuse Flashcards by Vanessa Darmos

Psychostimulants

Dexamphetamine
Methyphenidate

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MoA of psychostimulants

block NET and DAT

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methadone MoA

long opioid agonist

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indication for methadone

opioid addiction

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disulfiram indication

alcohol deterrent

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disulfiram MoA

Accumulation of ADH leading to sympathetic overactivity (negative effects)

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Acamprosate indication

alcohol cravings

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Acamprosate MoA

glutamate

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naltrexone indication

opioid abuse

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naltrexone contraindications

liver failure
current opioid use

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bupropion indication

smoking cessation

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buproprion MoA

SRI of dopamine and NA

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Contraindications of bupropion

seizures
bipolar (its an antidepressant)
eating disorders

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MoA of varenicline

nicotinic acetylcholine receptor agonist

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Effects of Verenicline

lessening cravings
lessening withdrawal
reduces positive effects

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flumazenil indication

reversal of benzo OD

Modafinil class

non-stimulant ADHD mx