Psychostimulants Flashcards
Stimulants vs Psychostimulants
Stimulants - stimulate nervous system and influence dopamine production
- affect blood pressure, alertness, and heart rate
- enhance norepinephrine (“rest or repose”) and dopamine (euphoric feeling)
Psycho stimulants have therapeutic value but highly susceptible to addiction
Types of Stimulants
Psychomotor
- release chemicals in the brain by stimulating CNS
- eg. adderall(, dexedrine, ritalin
Psychomotor stimulants
- cocaine, amphetamines, nicotine, caffeine , antidepressant
Psychotomimetic drugs/ Hallucinogens
- altering perception fo surrounding environment
- eg. Lysergic acid, psilocybin, mescaline
Convulsants & Respiratory stimulants
- have no clinical applications
- used for research since mechanism of action is unknown
- eg. Bicuculline, Picrotoxin, Doxapram, Pentlenetetrazol
Cocaine
Cocaine
- leaves of coca plant
- snort, rub it in, inject
- crack = the vapor of the heat from cocaine crystal; crackling sound while heated
Short term - happiness, energy, hypersensitivity, paranoia
long term - lungs and nose
duration and intensity depends on type of intake method
Amphetamines
Increase noradrenaline/norepinephrine and dopamine in the brain
- bind to receptors to block them (antagonist), dopamine stays longer in brain as a result
- results in wakefulness and alertness
- adderall
withdrawal - headaches, dizziness paranoia
Methylphenidate
Increase level of dopamine - pleasure like feeling
ADHD can be treated with these drugs but do not go over prescription to prevent addiction; not the first choice of intervention
- eg. ritalin
causes a feeling of pleasure but increases bloodpressure and heart rate
Methamphetmine
is its own drug. not a category like amphetamines
longer half life than cocaine, thus, harder withdrawal effects
is more potent
restless, appetite, depression, anxiety, dry mouth, psychosis
a medication against obesity because of decreased appetite effects
Depressants
Bariturates
benzodiazapines
Inhalants
- aerisols, paint, gas, glue
- less aircirulation
less psychostimulants than depressants
Medical and Nonmedical uses
Alkaloid ephedrine from plant Ephedra vulgaris - origin of psychostimulant drugs
used in China as a herb Ma Huang
amphetamines is limited to ADHD treatments