Psychosis Flashcards
Atypical drugs
Clozapine
Olanzapine
Quetiapine
Typical antipsychotics
Chlorpromazine
Haloperidol
Inhibit different nts act as d2r antagonists
What are antipsychotics good at controlling?
Positive symptoms
Antagonistic effect at da r
Antipsychotic action
Endocrine ffects
Extrapyramidal effects
Antagonistic effect at histamine r
Sedation
Ach muscarinic antagonisitc effects
Blurred vision, increaed eye pressure, dry mouth eyes, urinary retention, constipation
Serotonin r antagonist
Weight gain
Alpha adreno r antagonistic effect
Orthostatic hypotension, failure to ejaculate, sedation
Which type of drug has fewer extrapyramidal side effects?
Atypical
Maybe due to lower potency for d2r in basal ganglia
Negative symptoms
Clozapine
Typical and atypical no good