Psychopharmacology

Question 1

Therapeutic index

Answer 1

The ratio between the dose that produces the desired effect in 50% of the animals tested and the dose that produces toxic effects in 50% of the animal tested

Question 2

Tolerance

Answer 2

A decrease in the effectiveness of a drug after repeated administrations

Question 3

Sensitization

Answer 3

An increase in the effectiveness of a drug after repeated administrations

Question 4

Antagonist

Answer 4

A drug that blocks or inhibits the effects of a neurotransmitter on the postsynaptic cell

Question 5

Agonist

Answer 5

A drug that facilitates the effects of a neurotransmitter on a postsynaptic cell

Question 6

Glutamate

Answer 6

An amino acid that is the principle excitatory neurotransmitter in the brain and spinal chord

Question 7

GABA

Answer 7

An amino acid that is a key inhibitor neurotransmitter to keep the brain stable

Question 8

Glycine

Answer 8

An amino acid that is the key inhibitory neurotransmitter in the lower brain and spinal chord

Question 9

Acetylcholine

Answer 9

Associated with muscular movement, REM sleep, learning, and formation of memories

Question 10

Dopamine

Answer 10

Associated with movement, attention, learning, reinforcing effects of abused drugs

Question 11

Norepinephrine

Answer 11

Associated with an increase in vigilance and attentiveness

Question 12

Serotonin

Answer 12

Associated with regulation of mood; control of eating, sleeping, and arousal; regulation of pain

Question 13

Dose-response curve

Answer 13

A graph of the magnitude of the effect of a drug as a function of the amount of drug administered l