Psychopharm Flashcards
What foods are high in serotonin
turkey tomatoes sunflower seeds avocados pineapples
When giving SSRI’s what bad reaction shoudl we monitor fo r
serotonin syndrom
What are the mani’s of serotonin syndrome
altered LOC sweating fever Tachycardia HTN hyperreflexia Diarrhea
Treatment for serotonin syn
Stop medication
Provide IV fluids
Cooling blankets
Antipyretics
What things increase risk of serotonin syn
MAOIs
TCA’s
St. Johns wort
What is a consideration for someone taking MAOIs and is starting SSRI’s or bupropion
discon the MAOI’s 14 days prior to starting the SSRI’s or bupropion
What medication do SSRI’s increase
warfarin
What medications increase SSRI levels
TCA’s
lithium
Do NSAIDS and anticoag’s taken with SSRI’s increasse risk fo bleeding
yes
What are TCA’s
tricyclic antidepressents
What do TCA’s do
inhbiit reuptake of serotonin and norepinephrine
sometimes blocks histamine and acetylcholine
What are some common side effects of TCA’s
anticholinergic effects like dry mouth photophobia blurred vision constipation
What are some serious side effects of TCA’s
cardia toxicity
What are some examples of TCA’s
amitriptyline
Amoxapine
What is a consideration with MAOI’s and TCA’s
severe HTN is a risk so dont take together
What medications are contraindicated with TCA’s
antihistamines opioids benzodiazepines alc MAOI's
What problems does TCA’s and opioids benzodiazepines alc cause
increased CNS depression
What do MAOI’s do
MAOIs increases the availability of norepinephrine dopamine, and serotonin
What foods should you avoid with MAOI’s and why
aged cheese red wine soy sauce salami bananas sauerkraut bec they have tyramine or tryptophan
What are some common side effects of MAOI’s
anticholinergic effects like dry mouth photophobia blurred vision constipation anx orthostatic hypotension
What is a serious side eff of MAOI’s
HTN crisis
What are some examples of MAOI’s
isocarboxzid
phenelzine
Tranylcypromine
What is a consideration with MAOI’s and antihypertensives
hypotension may develop
What should you do for MAOI and antihypertensive pats
monitor BP and notify MD of significant drop
What analgesic may cause hyperpyrexia when given with MAOIs
meperidine
What food may increase the risk of HTN with MAOI’s and why
caffeine and phenylethylamine
bec they cause vasoconstriction
What conditions is bupropion contraindicated
pregnancy seizure disorders MAOIs anorexia nervosa bulimia nervosa
What classes of meds are given as anti anx
benzodiazepines,
barbiturates,
beta-blockers