Psychopathology/DSM Flashcards
Prevalence and Gender ratio of ID
1% of population (of these – 85% mild severity)
Male to female is 1.5:1
Language disorder (brief summary)
Difficulty acquiring and using language (comprehension or production)
Speech Sound disorder (brief summary)
Articulation (eg lisps)
What are the severity levels and specifiers for ASD?
Level 1 (require support) Level 2 (require substantial support) Level 3 (require very substantial support) Specify with/without intellectual impairment and language impairment.
Prevalance and gender ratio for ASD
1%, male to female 4:1
Prevalence and gender ratio for ADHD
5% children and 2.5% adults
Males to females 2:1
Common associated features of ADHD
Low frustration tolerance, mood symptoms, social rejection/conflict.
Prevalence of SLD
5-15%
Differential between Tourette’s and other tic disorders
Tourettes has multiple motor and 1 or more vocal tics
Motor/Vocal tic disorders only have one type.
Differential tics vs stereopies
Stereotypies are consistent and rhythmic, Tics are variable and brief
Symptoms of Psychosis (5)
Delusions, Hallucinations, Disorganized speech, Grossly disorganized or catatonic behavior, negative symptoms.
Brief Psychotic Disorder
At least one of: delusions, hallucinations, disorganized speech.
Duration 1 – 30 days
Schizophreniform disorder
At lest 2 symptoms (must include one of delusions, hallucinations, or disorganized speech)
Duration 1-6 months
Schizophrenia
“Active phase” at least one month with 2 symptoms, followed by a prodromal/residual phase with attenuated symptoms or negative symptoms lasting longer than 6 months
Neurotransmitters involved in psychosis
Dopamine, Glutamate, serotonin.
Dopamine hypothesis of schizophrenia:
Positive symptoms are caused by too much dopamine in subcortical striatal areas.
Negative symptoms are caused by not enough dopamine in prefrontal cortex.
Brain regions in schizophrenia
Enlarged ventricles, small cortex, small thalamus.
Underactive frontal lobe.
Temporal-limbic-frontal network and striatum (caudate nucleus, putamen, nucleus accumbens).
Common comorbidities of schizophrenia
Anxiety, OCD, tobacco use.
Prevalence and heritability of Schizophrenia
Lifetime prevalence around 0.5%.
Identical twins .5, sibs .1 concordance.
Onset and course of schizophrenia
Usually early 20s for males and late 20s for females.
Positive symptoms decrease with age, negative/cognitive persist
Prognostic factors in schizophrenia
Better prognosis: Female, late and acute onset, comorbid mood symptoms, mainly positive symptoms, precipitating stressor, good prior adjustment.
Worse prognosis: lack of insight, high expressed emotion families (criticism/hostility)
Treatment for schizophrenia
Antipsychotic drugs, CBT, cognitive remediation, family psychoed, social skills training, ACT, supported employment
Schizoaffective Disorder
Concurrent mood episode AND one month of 2 active symptoms, AND at least 2 weeks with delusions/hallucinations without mood symptoms.
Delusional Disorder
1+ delusions for at least one month without any other psychotic symptoms, and without overall impairment in functioning
Subtypes of delusion disorder:
Erotomanic (someone is in love with them), grandiose, jealous (spouse unfaithful), persecutory, somatic, unspecified
Treatment for delusions
Medication, CBT for delusions (forming alternative explanations and evaluating both, starting with less closely held aspects)
Family therapy
Characteristics of Mania
Necessary: Elevated/Expansive/Irritable mood AND increased activity or energy for most of the day, nearly every day. Other symptoms: Inflated self-esteem/gradiosity Decreased sleep Pressured speech Flight of ideas/racing thoughts Distractibility Increased activity (goal-directed or non-goal directed) Excessive risky behavior
Manic Episode vs Hypomanic
Both have:
Elevated/Expansive/Irritable mood AND increased activity or energy for most of the day, nearly every day.
Manic: Hospitalization AND/OR At least 1 week of “severe marked impairment” AND/OR psychotic features
Hypomanic: At least 4 days, no psychosis, less impairment
Criteria for Bipolar 1
One manic episode
Criteria for Bipolar 2
One hypomanic and one major depressive episode
Cyclothymic disorder
Several hypomanic and depressive symptoms that don’t meet full criteria for an episode. Sx are present at least half the time (periods of remission shorter than 2 months).
Adults: at least 2 years, Children: At least 1 year
Typical onset for bipolar
Late teens to mid 20’s. BP1 is earlier. Often preceeded by a stressor.
Neurotransmitters involved in Bipolar
Norepinephrine, Serotonin, Dopamine, Glutamate
Brain regions involved in Bipolar
Prefrontal cortex, amygdala, hippocampus, basal ganglia
Therapies for Bipolar
Family focused therapy, CBT, psychoed, “interpersonal and social rhythm therapy”
Medications for Bipolar
Lithium for Classic BPD
Anticonvulsants and 2nd gen Antipsychotics for atypical features
Frequent comorbidities for bipolar:
ADHD, anxiety, Substance use, sleep disorders, eating disorders, disruptive disorders
Symptoms of depression (10)
Depressed mood nearly every day (children: includes irritability) Diminished interest/pleasure Weight/appetite change Sleep disturbance Psychomotor agitation/retardation (observable by others) Fatigue/loss of energy Feel worthless/guilty Can’t concentrate or indecisive Thoughts of death/suicidal ideation
Depressive episode criteria
At least 5 symptoms (including mood or anhedonia) every day for 2 weeks
Depressive episode with anxious distress
Depressive episode with 2 of: feeling keyed up/tense Restlessness Trouble concentrating due to worry Fearful something awful will happen Feel they may lose self-control
Mood episode with mixed features
A depressive, manic, or hypomanic episode with at least 3 features of the “opposite” type of episode.
Mood disorder with rapid cycling
At least 4 episodes per year, with either 2 months of remission in between or switch to episode of the opposite pole.