Psychobiology Flashcards

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1
Q

What is stress?

A

Can be a stimulus stressors are events that place strong demands on us stress can be a response

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2
Q

What are the 3 stages of General Adaption Syndrome?

A

1: Alarm reaction - shift to sympathetic dominance causes increased arousal 2: Resistance - endo system releases hormones to maintain increased arousal 3: Exhaustion - adrenals lose ability to function normally.

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3
Q

Define stress using primary and secondary appraisal (transactional definition of stress)

A

Combination of stimulus and responses. Pattern of cognitive appraisals, emotional reactions, physiological responses and behavioural tendencies that occur in response to a perceived imbalance between situational demands (primary appraisal) and the resources needed to cope with them (secondary appraisal).

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4
Q

What is the primary appraisal?

A

Perceived imbalance between situational demands

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5
Q

What is the secondary appraisal?

A

Perception of availability of resources needed to cope with them

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6
Q

Diagram of stress?

A
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7
Q

Give an example of a cognitive appraisal

A

Exam

primary appraisal - how hard will it be

secondary appraisal - do i know enough

Take into account potential consequences of failing with regards to likelihood and severity

Pyschological meaning of consequences may be related to beliefs about yourself

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8
Q

What is the Yerkes-Dodson Law?

A

Normal distribution curve

At low arousal you have poor performance but at really high levels of performance you also have poor performance due to anxiety.

Optimal level of performance found at around medium arousal.

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9
Q

How did support affect health behaviours leading up to exam in steptoe1996?

A

Those with more support showed decrease in number of cigs and alky when exam time came.

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10
Q

Summarise the pathway of stress to disease

A
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11
Q

How are anxiety and heart disease linked?

A

anxiety showed 52% increased risk to CVD

Independent of traditional risk factors - obesity, smoking

Anxiety management future CVD management technique.

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12
Q

List some features of Type A behaviour

A

Time urgency

Free-floating hostility

Hyperaggressiveness

Focus on acomplishment

competitive and goal driven

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13
Q

How are type A behaviour and cardiovascular health linked?

A

Type A behaviour patterns doubled the risk of develpoing CHD in healthy males, type A accounted for 31% increased risk when compared to type B (patience, serenity, not very time urgent)

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14
Q

Which factor of Type A behaviour is thought to be key behavioural factor to CHD?

A

HOSTILITY

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15
Q

What is mechanism for personality affecting actual health with regard to CHD?

A

Poor health behaviour - increased physiological resoponse to stressors - endothelial dysfunciton - atherosclerosis

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16
Q

What other traits blah have been associated with CHD?

A

Depression - increased risk for onset of CHD, CHD patients have 2.5 times higher risk of of mortality when depressed - physiological and health behaviour changes

17
Q

What are the different mechanisms for coping with stress?

A
18
Q

Define approach and avoidance

A

Approach = activity orientated towards threat e.g. problem solving and planning a response

Avoidance = away from threat e.g. denial, may find it difficult to engage in conversation about health

Utility of coping style depends on situation

19
Q

Swearing and pain relief?

A

perceived pain score was down when people swore with pain

However, heart rate was higher when people swore with pain

20
Q

Elaborate on the importance of social support

A

Individuals with adequate social relationships have a 50% likelihood of survival compared to those with insufficient social relationships

Exert independent effect beyond pyhsiological role that is comparable with stopping smoking

21
Q

Provide an example of social support benefitting the ting

A

Breast cancer groups control and experiment

Those with support group had a 1/3 more survivors over a 4 year period

22
Q

How does branding of medication help?

A

Neurofen ibuprofen was shown to better improved perceived feeling compared to non-branded, even branded placebo did better than non branded placebo.

23
Q

Define the placebo effect

A

An inactive substance such as sugar or saline can sometimes improve a patient’s condition because person has expectation it will be helpful.

24
Q

Define the nocebo effect

A

negative effect that occurs after receiving treatment even when the treatment in inert or a sham L00000L

Warnings of side effects will increase likelihood that patient feels said side effects

25
Q

What are the physiological framing mechanisms involved with placebos?

A

Framing

Social/experimental learning

classical conditioning - behaviour, placebo may be able to elicit the unconditioned response from controlled stimulus now being the placebo not unconditioned stimulus(active treatment)

26
Q

What are the clinical implications for placebo?

A

Effect of therapies can be affected by their presentation - not specific to placebo.

placebos don’t have negative side effects

can be useful where there is a psychological component

27
Q

Were open placebos successful?

A

When the patient knows they are taking a placebo

Showed global improvement, symptom improvement, relief improvement and better QoL in IBS patients compared to no treatment.