Psycho Psycho Flashcards by anitha roy

Rx for Tourette syndrome

Behavioral Rx
1. Antipsychotic
-fluphenazine
Risperidone

DA depleter- tetrabenazine
Alpha 2 agonist-guanfacine

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Rx for binge eating disorder

Amphetamines

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High potency vs low potency antipsychotic

High potency:
Haloperidol
Trifluphenazine
Fluphenazine

EPS

LOW POTENCY: chlorpromazine, thioridazine
Anticholinergics,antihistaminics,alpha 1 blockers

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Opthalmic complication of antipsychotic

Chlorpromazine: corneal deposits
Thioridazine: retinal deposits

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Buspirone is used for….

GAD

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C/i drug with linezolid

MAOB inhibitors

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MOA for varencicline

Nicotinic Ach partial agonist

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DOC for
Heroin abuse
Prevent relapse

Acute opioid overdose

Methadone

Buprenorphine,naltrexone

Naloxone

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What’s the diff between naloxone and naltrexone ?

Naloxone: short acting opioid

Naltrexone: long acting opioid

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Pathophysiology of tardive dyskinesia

Chronic use -DA receptor supersensitivity

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Characteristic of panic disorder

Panic with no apparent cause-no trigger no situation

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Diagnostic of specific phobia

Anxiety >6mo

Avoidance behavior

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Physical finding of methamphetamine abuse

Meth teeth-brown,cracked teeth and tooth decay

Skin sores, teeth grinding

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Good thing and bad thing about bupropion

Good thing: no weight gain, no sex prob

Bad thing:
Can’t give for insomnia, bulimia, anorexia

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Diff between mania and hypomania

> 3 sms of DIGFAST for > 1 week

Hypo: > 4 days

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C/f of adjustment disorder

3-6 mo

If >6mo: GAD

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Characteristic of disruptive mood dysregulation syndrome

Before 10 years

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Biofeedback is done for….

Pain disorder

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Personality disorder usually given ….

Psychodynamic psychotherapy

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If patient has insomnia or anxiety rule out …..

Alcohol use disorder

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Rx for serotonin syndrome

Discontinue the drug
BZP
cyproheptadine

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Diff between conduct and oppositional use disorder

Oppositional use: no stealing or aggression towards towards people

But patient is hostile and defiant towards authorities (home and school) for >6months.

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5 ps of AIP

Psycho prob
Poly neuropathy 
Painful ab 
Port wine pee
Ppt by CYP

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Findings of Wilson’s disease (5)

Dysarthria 
Dystonia
Depression 
Tremors 
Parkinsonism

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Signs of inhalant abuse (3)

1. Transient euphoria:foll by LOC of 15-45 mins 2. Dermatitis: glue sniffers rash: around mouth and nostrils 3. Increased LFT

Chronic abuse with NO causes .......

Vit b12 def—>polyneuropathy

Drug of choice for pediatric depression

Fluoxetine-no weight gain issues

What is ectasy?

Synthetic amphetamines with mild hallucinogenic properties

What does ectasy do?

Taken before parties-causes euphoria, sociability,empathy and sexual desire

Manifestation of ecstasy intoxication

Amphetamines toxicity + serotonin toxicity + decrease in serum sodium ( drug induced SIADH)

How to diagnose somatic symptom disorder?

> 1 somatic symptom—> distress and functional impairment for >6 mo

Rx for PCP intoxication

BZP- to decrease psychomotor agitation

Depersonalisation derealization can be seen jn ...... cases(2)

Depersonalisation derealization d/o | Panic attacks

Diff between schizoaffective vs bipolar 1

Hallucinations present when mood is stable is schizoaffective

S/e of valproate

Hepatotoxicity within 6 mo of Rx Tremors TCP Alopecia

C/f of cocaine withdrawal

Increased energy followed by pronounced fatigue Increased dreaming,sleep,appetite

Guidelines for mgt of depression in remission

Unipolar dep single episode: —continue for 6mo; if remission,withdraw gradually ``` Chronic dep(>2 episodes) + suicide attempt: —-continue for 1-3 years ``` >3 episodes + suicide attempt: —-continue indefinitely

MOA of valbenazine

Vesicular monoamine transporter 2 inhibitor

1st line Rx for alcohol use

Naltrexone + acamprosate

MOA of acamprosate

Glutamine inhibitor Maintain abstinence Avoid in CKD patients

Time period for schizoaffective disorder C/I of haloperidol Fear of scrutiny/ Embarassment/ being -ve judged S/o......

>2 weeks Seizures Social anxiety disorder

C/f of narcolepsy (3)

Cataplexy Hypnogogic and hypnopompic hallucination Short REM sleep latency

CSF levels of narcolepsy Psychosis in parkinsons Rx....

Low levels of hypocretin-1/ orexin A Quetipine, pimavanserin

2nd gen antipsychotics with low metabolic risk

Ziprasidone Aripiprazole Lurasidone

.......levels are ass with depression What are decreased in depression?

Increased cortisol levels - secondary of hypothalamic pituitary adrenal axis REM sleep latency Decreased slow wave sleep Decreased hippocampal and frontal lobe volumes

NE and DA reuptake inhibitor 5HT and NE reuptake inhibitor is moa of.... MOA of Risperidone

Bupropion SSRI 5HT2A and D2 receptor blocker

Antidepressant with dose dependant HTN Rx for nightmares in PTSD

Venlafaxine Low dose : 5 HT reuptake inhibitor High dose: NE reuptake inhibitor Prazosin

Candidates considered for long acting antipsychotics? (3)

1. Those who live alone 2. Poor adherence to meds 3. Poor insight

Special feature of PTSD

May occur immediately after trauma or maybe delayed for months

Structural abnormalities associated with OCD

1. Orbitofrontal cortex | 2. Basal ganglia

Accelerated head growth is seen in......

Autism

“Slow finger tapping” is a feature of....... | Seen in.....

Bradykinesia Seen in drug induced Parkinsonism

S/e of growth hormone (4)

Taken to improve athletic ability Causes: 1. Hyperglycemia 2. Sodium retention 3. HTN 4. Swollen hands,joints, muscle pain

C/f of intellectualization

Avoid anxiety by focusing on non emotional aspects

Describe delayed sleep wake disorder

Night owls | Insomnia plus daytime sleepiness

Rx for delayed sleep wake disorder

Light, behavioral Rx

Advanced sleep wake disorder-describe

Sleep af 7pm, early morning insomnia

Describe shift work disorder

Normal circadian rhythms | Required to do night shifts—> increased daytime sleepiness

MRI of PML vs HIV dementia

PML: asymmetrical lesions HIV dementia: diffuse lesions

Ecstasy (MDMA) vs bath salts intoxication

Ecstasy: increase in euphoria, intimacy Severe hyperthemia Bath salts: severe agitation,psychosis,myoclonus, Seizures Increased HR and BP

Most distinguishing feature of bile salt intoxication

Prolonged duration of effects | (days->weeks)

ADHD presents at ......age Autism presents at .......age

ADHD: less than 12yrs Autism: Severe: 5 yrs Less severe: more than 5 yrs

What is social communication disorder?

Problem with verbal and non verbal communication( eye contact,body language etc)

Landau kleffner syndrome-define

Happens at 3-6 yrs of age | Severe epilepsy—> regression in language

Imaginary friend is normal upto .....age When should one assess problem with imaginary friend?

3-6 yrs If having disorganised speech or behavior Social isolation Regression of milestones