Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Mccqe1 Red Star Questions > Neuro Flashy > Flashcards

Neuro Flashy Flashcards

1
Q

CSF features of CJD (4)

A

Neuron specific enolase
14-3-3 protein
S100
Tau protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mri of CJD s/0

A

Signal amplification in:
Basal ganglia
Head of caudate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Triad of Ménière’s disease

A

Vertigo
Hearing loss
Tinnitus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Symptoms of hyponatremia due to SIADH

A

Loss of appetite
N/V
Seizures
Altered level of consciousness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dx of IIH

A

LP-pressure >20-25

Normal CSF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MOA of acetazolamide

A

Decrease CSF production in choroid plexus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mees lines suggest exposure to ….

A

Arsenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rx for arsenic toxicity

A

Gastric lavage
Activated carbon
Dimercaprol,succimer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

C/f of lead toxicity (3)

A

Behavioral probs
Gingival hyperpigmentation
microcytic hypochromic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

S/e of carbamazepine

A

Vertigo
Sedation
Diplopia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Polymyositis vs dermatomyositis on bx

A

Polymyositis:
intrafascicular inflammation with T cells

Dermatomyositis:
Parafascicular ,perivascular infiltration with B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

C/f of inclusion body myositis

A

Asymmetric proximal and distal muscle weakness-selective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Egs of NMDA antagonists

A

Ketamine

Memantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Define Chiari 2 malformation (4)

A

Myelomeningocele
Caudally displaced tonsils
CSF obstruction
Syrinx of hydrocephalus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Facial erythema stretch marks blurry vision and headache s/0…

A

Polycythemia vera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cause of DRESS syndrome

A

Carbamazepine toxicity
Drug reaction with Eosinophilia and systemic signs: fever,mobiliform rash-erythema,LAP.

Acute HSS- 2-8 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

S/e of phenothiazine

A

Impaired thermoregulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

C/f of acute porphyria

A

Ab pain,peripheral neuropathy,psycho

Ppt by drugs, alcohol,purple pee

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tumor ass with Sturge weber syndrome

A

Leptomeningeal angioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Disease ass with Romberg sign

A

Neuro syphillis-tabes dorsalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Rx for chronic tension headache

A

Amitryptilline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Rx for cryptococcal meningitis

A

AmphoB + flucytosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Rx to prevent attacks of MS

A

IFN B + glatiramer acetate followed by natalizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

C/f of meningococcal meningitis (3)

A
  1. Non blanching petechial rash
  2. Signs of DIC, shock
  3. Adrenal gland failure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Prevention of meningococcal meningitis

A

Polysaccharide conjugate vaccine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Complication of mumps meningitis

A

Pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Dx test for Lyme disease

A

ELISA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Pathophysiology of Lyme disease

A

Toxin preventing AcH release at NMJ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Rx for Lyme disease

A
  1. Remove tick
  2. Doxy-adults, amoxicillin-kids
  3. Disseminated- ceftriaxone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Contraindications of TCA (2)

A

Glaucoma

LBBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Rx for acute angle closure glaucoma (2)

A

Beta blockers

Apraclonidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Systemic Rx for acute angle closure glaucoma

A

Acetazolamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

C/I Rx for angle closure glaucoma

A

Epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

C/f of SSPE (4)

A 
Dementia 
Myoclonus 
Epilepsy 
Coma/death 
  —7 yrs post infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Inheritance and prognosis of Tay Sachs disease

A

AR

prognosis: death by 4 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Bx of Tay Sachs disease

A

Lysosomes with onion skin appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

C/ f of adrenoleukodystrophy (5)

A 
Young male with 
Deteriorating vision 
Hearing loss
Motor,cognitive deficits 
Dementia 
Adrenal insufficiency

—-lethal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Inheritance of adrenoleukodystrophy

A

X-linked

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Pathophysiology of adrenoleukodystrophy

A

Mutation of ATP binding cassette transporter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Rx for adrenoleukodystrophy

A

Diet -lipids + steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Peripheral neuropathy and microcytic anemia is due to …….

A

Isoniazid toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Criteria to evacuate subdural hematoma

A

If >10mm
If >5mm with midline shift
Mod-severe cognitive impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Hearing in patients with otosclerosis is seen with….

A

Noisy environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Speech pattern of otosclerosis

A

Soft monotonous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Schtwarz sign is ass with….. define

A

Otosclerosis

Reddish hue in the tympanic membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Dx exam of otosclerosis shows …..

A

-ve rinne test
No lateralization in weber
BC>AC

47
Q

Noise induced hearing loss s/o….

A

Sensorineural hearing loss

48
Q

1st line antipsychotic drug is…..

A

Olanzapine

49
Q

S/e of Risperidone (2)

A

Hyperprolactinemia

Gynecomastia

50
Q

S/e of chlorpromazine (2)

A

EPS, anticholinergic symptoms

51
Q

ABG of Cushing’s syndrome

A

Hypokalemia
Hypernatremia
Metabolic alkalosis

52
Q

Bx of CNS lymphoma s/0….

A

Large lymphocytes with irregular nuclei

53
Q

Ct of vascular dementia shows….

A

Lacunar infarct in frontal region

Hypodense periventricular regions

54
Q

Pathophysiology of Sydenham’s chorea

A

Type 2 HS to strep Ab leading to I.F of basal ganglia and cortex

55
Q

Pathophysiology of syringomelia

A

Injury to decussating fibers in cervical and upper thoracic cord

56
Q

Paralysis of lower lip happens in ….

A

Injury to marginal mandibular br of facial nerve

Early complication of parotidectomy

57
Q

Neuronal deficits seen in churg Strauss

A

Loss of ulnar sensation plus foot drop -mononeuritis multiplex

58
Q

Rx of churg Strauss

A

GC

59
Q

M.c cause of hypopituitarism in children is….

A

Craniopharyngioma

60
Q

Complication of acromegaly

A

Ventricular hypertrophy —> decreased C.O

61
Q

Risk factors of peripheral neuropathy

A

Compression stockings

62
Q

Complication of acrondoplasia

A

Brain stem compression and spinal stenosis secondary to compression of foremen magnum

63
Q

Rx of meningitis in different age groups

A

<1 month: ampicillin + cefotaxime

1 mo-50 yrs : vancomycin + 3rd gen cephalosporin

> 50yrs: vanc+ 3rd gen cephalosporin + ampicillin

Immunocompromised: vanc+ amp+ cefepime\mero

Hospital acquired:
vanc + ceftazidime\cefepime/mero

64
Q

When do you add dexamethasone to meningitis?

A

When you suspect pneumococcal/HiB meningitis

65
Q

When you consider adding doxycycline to meningitis?

A

Tick bite in endemic areas

66
Q

Bull’s eye maculopathy seen in……

A

Chloroquine retinopathy

67
Q

S/e of phenytoin

A

Gingival hyperplasia

68
Q

Drug associated with sedation, weight loss, kidney stones?

A

Topiramate

69
Q

S/e of phenytoin (7)

A
  1. Gingival hyperplasia
  2. Hirsuitism,SJS
  3. Megaloblastic anemia
  4. Nystagmus
  5. Ataxia
  6. Peripheral neuropathy
70
Q

How does aminoglycosides cause ototoxicity?

A

Damages cochlea, and hair cells

71
Q

Which drugs increase likelihood of aminoglycoside toxicity?

A

Loop diuretics

72
Q

C/f of cavernous sinus thrombosis (3)

A

Periorbital edema
CN 6 palsy
sinusitis

73
Q

Rx for cavernous sinus thrombosis

A

Acute phase: heparinisation

Ab Rx in infections

74
Q

C/f of progressive supranuclear palsy? (8)

A 
Parkinsonism + 
vertical gaze palsy
              External opthalmoparesis
Frontal lobe signs -apathy 
Postural instability 
Dysarthria, dysphagia, dementia
75
Q

MRI of progressive supranuclear palsy

A

Hummingbird sign-

midbrain atrophy + intact pons

76
Q

C/f of neurocysticercosis (4)

A

Headache, blurry vision, seizures, myalgia

77
Q

Examination of neurocysticercosis

A

Subretinal cysts

78
Q

Dx of neurocysticercosis (2)

A

CSF: eosinophils

MRI: ring enhancing lesions

79
Q

What is mulder’s sign?

A

Seen in Morton’s neuroma

Pain and click when pressure is applied to sole of foot between metatarsal heads

80
Q

Pathophysiology of Morton’s neuroma?

A

Entrapment/enlargement of one of the plantar digital nerves

81
Q

Risk factors for Morton’s neuroma

A

Wearing high heel narrow shoes

82
Q

C/f of spinal shock (3)

A

Flaccid areflexic paralysis
Hypotension
Bradycardia

83
Q

Which reflex is absent in spinal shock?

A

Bulbocavernous reflex

84
Q

Risk factors of interventricular hge

A

Maternal chorioamnionitis + hypoxia

85
Q

Muscle biopsy of inclusion body myositis S/o ….

A

Vacuoles within muscle cells

86
Q

Define CIDP

A

Symmetric motor and sensory deficits for 2 months

87
Q

Pathophysiology of CIDP

A

GMI ganglioside auto ab

88
Q

Rx of CIDP

A

Iv Ig, plasmapheresis + GC

89
Q

Anomalies seems with cri du chat

A

Cardiac anomalies

90
Q

Antidote for methanol poisoning

A

Fomepizole

91
Q

Dx of methanol poisoning

A

Increased anion gap,

increased osmolar gap

92
Q

P/E of otitis media externa

A

Retracted TM

93
Q

Recurrent otitis media externa causes…..

Rx for recurrent otitis media

A

Ventilation tube insertion

Conductive hearing loss

94
Q

S/e of entacapone

A

Nausea, dyskinesia

95
Q

MRI of cerebral palsy

A

Periventricular Leukomalacia

96
Q

Dx test for neuroblastoma

A

Homovanillic acid and vanillylmandelic acid in urine

97
Q

M.c location of meningiomas (3)

A

Falx cerebri
Supratentorial convex surface
Sphenoidal wings

98
Q

Examination of foster Kennedy syndrome (3)

A

I/L atrophy of left optic nerve
C/L papilledema
Anosomia

99
Q

Cause of foster Kennedy syndrome

A

Frontal lobe tumors-m.c cause of meningiomas

100
Q

C/f of oculomotor nerve palsy (3)

A

Ptosis
Abduction,
Depression with slight intorsion of affected eye.

101
Q

Blood vessel spared in DM oculomotor nerve palsy

A

Supplying superficial parasm fibers

102
Q

M.c cause of non purulent conjunctivitis

A

Adenovirus,HSV

103
Q

M.c cause of b/l conjunctivitis

A

Adenovirus

104
Q

M.c cause of U/L conjunctivitis

A

HSV-1: kids/ adults

HSV-2: neonates

105
Q

TORCH infection associated with pulmonary and hepatic granuloma

A

Listeria

106
Q

Complications of maternal listeriosis (2)

A

Spontaneous abortion

Preterm labor + chorioamnionitis

107
Q

Sequels of uncal herniation

A

Midbrain displacement + cerebral peduncle
—->
I/L hemiparesis + UMN signs

108
Q

Dx of lateral femoral cutaneous neuropathy

A

Reproduce numbness by tapping on inguinal ligament

109
Q

Drug that increases risk for PML

A

Natalizumab-> decrease lymphocyte migration in CNS

110
Q

Pathophysiology of PML

A

Reactivation OF JC virus infection in CNS—>PML

111
Q

Patient with ethylene glycol toxicity

A

AMS, Tachypnea,hypocalcemia —tetany

112
Q

Dx of ethylene glycol toxicity

A

Oxalate crystals in urine
Hypocalcemia
Gap met acidosis

113
Q

Rx for ethylene glycol toxicity

A

Fomepizole

H.D if severe metabolic/organ dysfunction

Mccqe1 Red Star Questions (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions