Psychiatry medications Flashcards
Examples of SSRI’s
Fluoxetine
Paroxetine
Citalopram
Sertraline
Which SSRI is preferred in patients in patients post MI?
Sertraline
How do SSRI’s work?
Inhibit reuptake of 5-HT
Increases synaptic 5-HT- desensitises 5-HT receptors
Side effects of SSRI’s
Sexual dysfunction
GI effects
Short termanxiety
What patients should citalopram not be given to?
Long QT interval
Which medications can SSRI’s interact with?
NSAIDs
Warfarin/Heparin
Aspirin
5-HT inhibitors (triptans)
How do TCA’s work?
Inhibit pre-synaptic reuptake of noradrenaline, serotonin & dopamine
Side effects of TCA’s
Constipation
Dry mouth
Blurred vision
Postural hypotension
What does MAO-A metabolise?
Noradrenaine
5-HT
Tyramine
What does MAO-B metabolise?
Dopamine
Tyramine
Phenylethamine