Psychiatry buzzwords Flashcards

1
Q

Third person auditory hallucinations

A

Schizphrenia

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2
Q

Mesocortical dopamine hypoactivity

A

Negative and cognitive symptomsinschizophrenia

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3
Q

Subcortical dopamine hyperactivity causes…

A

Psychosis

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4
Q

What is thetuberofundibular pathway in the brain concerned with?

A

Prolacin release

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5
Q

What is the nigrostriatal tract concerned with?

A

Extra-pyramidal motor movements

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6
Q

What is the mesolimic system invloved in?

A

Motivation & reward

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7
Q

What is the mesolimbic pathway dysregulated in?

A

Schizophrenia

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8
Q

How does Da blockade compare to Da agonism in terms of clinical pressentation?

A

Da blockade - Depression

Da agonism - psychosis

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9
Q

Side effects of clozapine

A

Agranulocyosis
Cardiomyocitis
Weight gain

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10
Q

Which of the atypical anti-psychotics causes the most weight gain?

A

Olanzapine

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11
Q

When is clozapine indicated?

A

When have been tried on 2 other anti-psychotics and need to be a consultant to prescribe

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12
Q

How is clozapine monitored?

A

Once a week for 6 months

Then once every 2 weeks fro 6 months then every 4 weeks thereafter and a month after discontinuation

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13
Q

What are the functions of the limbic system?

A

M2 - Memory, Motivation
O- Olfaction
V - Visceral afferents
E - Emotion

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14
Q

What are the brain changes in schizophrenia?

A

Reduced frontal lobe volume (and grey matter)
Enlarged lateral ventricles
Reduced grey matter in the temporal cortex

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15
Q

What is pressure of thought

A

Varied ideas in abundance (characteristic of mania but also seen in schizophrenia)

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16
Q

What is poverty of thought?

A

Patient reports lack/absence of thoughts

17
Q

What is thought blocking?

A

Abrupt and complete interruption of stream (strongly associated with schizophrenia)

18
Q

What is flight of ideas?

A

Quickly moving from one topic to anoher but there is a link unlike knights move thinking

19
Q

What is knights move rhinking?

A

Quicly moving fromonetopic to another whenthere doesn’tseemtobealink

20
Q

When is knights move thinking seen?

A

Inbipolar during mania

21
Q

How are EP side effects treated?

A

Procyclidine

22
Q

WHat is the role of the amygdala?

A

Involved in normal response to threat

23
Q

What is the relationshipp between the PFC and the amygdala?

A

PFC dampens down amygdala response to threat

24
Q

What s the steps of management of OCD?

A
  1. SSRI
  2. SSRI
  3. TCA or SSRI
25
Q

What TCA is used in OCD?

A

Clomipramine

26
Q

What are the cut off’s forlearning diabilities?

A
70-80 = borderline 
50-69 = mild 
35-49 = moderate
20-34 = severe 
<20 = profound
27
Q

What is Becks triad?

A

Negaive feelings about self, world & future

28
Q

What symptoms do NMDA antagonists produce?

A

Psychotic symptoms

29
Q

What should be used to treat alcohol withdrawal?

A

Chlordiazepoxide

30
Q

When would alcohol withdrawal seizures occur?

A

Within 48 hours

31
Q

When would delirium tremens occur?

A

Between 48 and 72 hours

32
Q

What can MAO inhibitors react with to cause hypertensive crisis?

A
Tyramine containing foods 
Ephridine 
Nasal decongestants 
TCAs 
Pethidine
33
Q

How is hypertensive crisis caused by MAO inhibitors treated?

A

Phentolamine infusion

34
Q

When should TCAs be avoided?

A

Cardiac problems or patients with suicidal intent