Psychiatry Flashcards
Which part of brain gives positive symptoms of scizophrenia?
Mesiolimbic (dopamine)
Difference between NMS and serotonin syndrome?
Sertonin syndrome has clonus and hyperreflexia
EPSE: Restlesness.
Clinical name? Management (3)?
Akathesia
Stop antipsychotic
Propanolol
Diazepine
Contraindication to lithium?
Renal failure
Symptoms of Neuroleptic Malignant Syndrome?
FALTER:
Fever
Autonomic instability (tachycardia, hypotension, tachypnoea, diaphoresis)
Leukocytosis
Tremor
Elevated CK
Rigor (hypertonia)
Management of NMS? (4)
Stop antipsychotic
Cooling IVT
Dantrolene (muscle relaxant)
Bromocriptine (dopamine agonist)
Which part of brain gives negative symptoms of scizophrenia?
Mesiocortical (serotonin/5HT1)
EPSE; order of when they occur.
(Acute) Dystonia (hours)
Akathesia (days-months)
Parkinsonism (months)
Tardive dyskinesia (years)
Side effects of lithium (5)?
Tetrogenic
Nephrotoxic
Hypothyroidism
Nephrogenic Diabetes Insipidus
Fine tremor
Symptoms of lithium toxicity, causes, mx?
Diarrhoea, drowsiness, slurred speech, confusion, dizziness, muscle twitching/tremor
Renal impairment: NSAIDs, ACE inhibitors, dehydration, diuretic use
Stop lithium, IVT, haemodialysis
What tests before starting antipsychotics? (3)
ECG for prolonged Q syndrome
Prolactin levels for hyperprolactinaemia
CVD risk factors (lipids, HTN, glucose)
EPSE: Patient has head turned one way and cannot move.
Clinical name (2)? Management (2)?
Torticollis of Dystonia
Stop antipsychotic
Benzotropine (anticholinergic)
Management of EPSE?
Expect which one? How to treat?
Stop antipsychotic/change to an atypical
Benztropine for acute episode
Akathisia (restlessness) needs propanolol or diazepine
Side effects of atypical antipsychotics (7)?
Weight gain
Hyperprolactinaemia
Increased CVD
Sedation
EPSE
Prolonged QT
Anticholinergic
