Psychiatry

Question 1

Third person auditory hallucinations

Answer 1

Schizophrenia

Question 2

Mesocortical dopamine activity

Answer 2

Negative and cognitive symptoms in schizophrenia

Question 3

Subcortical dopamine hyperactivity

Answer 3

Psychosis

Question 4

Mesolithic Da blockade

Answer 4

Depression

Question 5

Mesolimbic Da agonism

Answer 5

Psychosis

Question 6

S/E of clozapine

Answer 6

Agranulocytosis
Cardiomyocitis
Lots of weight gain

Question 7

When to prescribe clozapine

Answer 7

Need to try 2 other anti-psychotics first & must be a consultant to prescribe

Question 8

Clozapine monitoring

Answer 8

Once a week for the first 6 months
Once every 2 weeks for the next 6 months
Every 4 weeks there after & one month after

Question 9

Limbic system functions

Answer 9

M2OVE:
Memory 
Motivation 
Olfaction 
Visceral afferents
Emotion

Question 10

Brain changes in schizophrenia

Answer 10

Reduced frontal lobe volume (and grey matter)
Enlarged lateral ventricles
Reduced grey matter in the temporal cortex

Question 11

Pressure of thought

Answer 11

Varied ideas in abundance

Seen in mania sometimes seen in schizophrenia

Question 12

Poverty of thought

Answer 12

Patient reports lack/absence of thoughts

Question 13

Flight of ideas

Answer 13

Quickly moving from one topic to another, with a link

Question 14

Knight’s move thinking

Answer 14

No link between phase A and B, seen in bipolar during manic phase

Question 15

Treatment of EPSE

Answer 15

Procyclidine

Question 16

Amygdala

Answer 16

Involved in normal response to threat

Question 17

Management of OCD

Answer 17

1. SSRI
2. SSRI
3. TCA or SSRI
4. SSRI or TCA

Question 18

TCA used in OCD

Answer 18

Chlomipramine

Question 19

Borderline LD

Answer 19

70-80

Question 20

Mild LD

Answer 20

50-69

Question 21

Moderate LD

Answer 21

35-49

Question 22

Severe LD

Answer 22

20-34

Question 23

Profound LD

Answer 23

<20

Question 24

Beck’s triad

Answer 24

Negative feelings about self, world and future

Question 25

NMDA antagonists

Answer 25

Produce psychotic symptoms

Question 26

Alcohol withdrawal

Answer 26

Chlordiazepoxide

Question 27

Alcohol withdrawal seizures

Answer 27

Within 48 hours

Question 28

Eosinophilic inclusions

Answer 28

Lewy bodies

Question 29

Risk of which crises with MAOIs

Answer 29

Hypertensive crises

Question 30

How to treat hypertensive crisis due to MAOIs

Answer 30

Phentolamine infusion

Question 31

When to avoid TCAs

Answer 31

Cardiac problems

Patients with suicidal intent