Psychiatry Flashcards
HY symptoms of depression
anhedonia
weight changes
sleep changes
poor concentration
first line agent in depression
SSRI ALONE (without any other antidepressants)
2 exceptions to SSRI use in depression
- depression + NEUROPATHIC PAIN
- depression +….
- fearful of weight gain
- sexual SE’s
- smoker trying to quit
tx depression + NEUROPATHIC PAIN
DULOXETINE
tx depression +….
- fearful of weight gain
- sexual SE’s
- smoker trying to quit
BUPROPION
choice of SSRI + antidepressant in depression
WRONGGGGGGG!!!!!
choose the cleanest= SSRI on its own
tx mild depression + sleep problems
MIRTAZAPINE,
since= antidepressant + sedative
what to exclude with presentation of mania
COCAINE and AMPHETAMINE use….
thus hx and toxicology
first line tx acute mania
LITHIUM
PC: 33yo man, brought to emergency room, bipolar, recently started on lithium, combative and punches nurse on the mouth. what’s the next best mgmt
ADEQUATE TX> admission to psychiatric unit;
ANTIPSYCHOTICS= first line tx
tx acute mania with severe symptoms
atypical antipsychotics
tx dysthymia
antidepressant meds + psychotherapy
tx atypical depression
MAOIs = usually the correct answer
seasonal affective disorder
phototherapy– 12-18 inches from source of 10,000 lux of white fluorescent light without UV wavelengths for 30 minutes each morning; eyes open, but don’t necessarily stare at the light
tx of normal bereavement
PSYHCOTHERAPY
never never never pharmacology
exception to strict diagnosis of major depressive disorder (5/9 for >6months, for 2 weeks)
if the symptoms are SEVERE ENOUGH
emergency situation of psychosis tx
IM atypical antipsychotic> haloperidol
tx of schizophrenia with psychotic episode, that is unresponsive to typical ro atypical antipsychotics
CLOZAPINE
avoid olanzapine in…
diabetics
obese patients
big SE of risperidone
MOVEMENT disorders
benefit of quetiapine
lower incised of movement disorders; thus ok to use in pots with movement disorders
avoid ziprasidone in patients with…
conduction defects since prolongs QT interval
clozapine monitor
CBC, since high risk of agranulocytosis
NEVER THE FIRST LINE TREATMENT
ariprazole use
ADJUNCT+ for major depressive disorer
only antipsychotic that can be used in pregnancy
lurasidone
LEAST likely drug to cause weight gain and diabetes in schizophrenia
- ARIPRAZOLE
2. ZIPRASIDONE
timing of movement side effects with antipsychotics…
HOURS–DAYS
ACUTE dystonia
tx of acute dystonia
benztropine
trihexyphenidyl
diphenhydramine
timing of movement side effects with antipsychotics…
WEEKS
AKATHASIA
tx of akathasia
DECREASE dose
beta blockers
switch to atypical antipsychotics
benzodiazepine
timing of movement side effects with antipsychotics…
GREATER THAN 6 MONTHS
tardive dyskinesia
tx of tardive dyskineasia
switch to atypical antipsychotics
LOWEST RISK OF tadive dyskinesia
CLOZAPINE
PC delusional disorder
NON-bizarre delusions NO impairment of functioning - still obeys law - goes to work - pays bills
> 1 month
tx of manic disorder– PSYCHOTIC FEATURES and AGITATION
ANTIpsychotics> lithium;
because RAPID action
PC panic attack
patient is presenting with autonomic hyperactivity
Tx panic attack
benzodiazepines: lorazepam, clonazepam, aprazolam
PC pain disorder
patient is giving you STORY/HISTORY of these symptoms
4+ autonomic hyperactivity,
Tx panic disorder
SSRI’s
tx of phobias
behavioural modification
and relaxation techniques
tx of performance anxiety– stage fright
BETA BLOCKERS; 30-60minutes before performance
tx of OCD
SSRIs
tx of OCD, when all the options are TCAs
CLOMIPRAMINE
tx of hoarding disorders
1: SSR’s
can also do behavioural mod or psychotherapy–CBT
what to exclude in diagnosis of PTSD
substance abuse— since will worsen the diagnosis
first line treatment for PTSD
paroxetine and sertraline
other tx options for PTSD
relaxation techniques
tx of GAD
1st line: SSRs
- venlafaxine
- buspirone
panic disorder vs. GAD
panic disorder: 30 minutes of symptoms
GAD: chronicity of symptoms >6months; constantly worried
lorazepam use
IM injection, thus EMERGENCY situations
clonazepam use
LONG HALF LIFE– if worried about addiction–
LOW addiction
chlordiazepoxide use
alcohol withdrawal
oxazepam use
alcohol withdrawal a/w LIVER problems
lorazepam non-emergency use
alcohol withdrawal a/w LIVER problems
alprazolam use
panic disorder and panic attack