Psychiatry

Question 1

give 2 examples of typical antipsychotics

Answer 1

haloperidol
chlorpromazine

Question 2

give 4 examples of atypical antipsychotics

Answer 2

clozapine
risperidone
olanzapine
aripiprazole

Question 3

MOA of typical antipsychotics

Answer 3

D2 receptor antagonists (block dopamine)

Question 4

MOA of atypical antipsychotics

Answer 4

act on dopamine and HT

Question 5

major side effect differences between typical and atypical antipsychotics

Answer 5

typical: extrapyramidal and increase prolactin levels
atypical: metabolic and weight gain

Question 6

which antipsychotic causes life threatening agranulocytosis and neutropenia
what do you monitor

Answer 6

clozapine

FBC for leukocytes

Question 7

give 4 examples of extrapyramidal side effects in antipsychotics

Answer 7

parkinsonism (bilateral resting tremor)
acute dystonia (muscle contraction causing torcollis)
akathisia (restlessness)
tardive dyskinesia (involuntary movements - chewing, pouting, blinking)

Question 8

which antipsychotic has the least effects on prolactin

Answer 8

aripiprazole

Question 9

medication to manage torcollis

Answer 9

procyclidine

Question 10

medication to manage tardive dyskinesia

Answer 10

tetrabenazine

Question 11

name some other side effects of antipsychotics

Answer 11

stroke/VTE
sedation
seizures
increased QT
sedation
galactorrhoea
antimuscarinic
neuroleptic malignant syndrome
reduced glucose tolerance
weight gain

Question 12

4 antimuscarinic side effects

Answer 12

dry mouth
blurred vision
constipation
urinary incontinence

Question 13

which antipsychotic increased the QT interval the most

Answer 13

haloperidol

Question 14

pyrexia and muscle stiffness on antipsychotic

Answer 14

neuroleptic malignant syndrome

Question 15

main side effect and management of SSRI

Answer 15

GI disturbance
give PPI

Question 16

which side effect does citalopram cause

Answer 16

prolonged QT interval
torsades de pointes

Question 17

which medication do SSRIs interact with to cause serotonin syndrome

Answer 17

MAOis

Question 18

dizziness, shock and anxiety on SSRI

Answer 18

discontinuation

Question 19

effect of using SSRIs during the third trimester

Answer 19

persistent pulmonary hypertension of the newborn

Question 20

which SSRI do you give post MI

Answer 20

sertraline

Question 21

which medication should you avoid whilst on SSRIs

Answer 21

triptans

Question 22

when are samples for lithium levels taken

Answer 22

12 hours post dose

Question 23

2 side effects of long term lithium use

Answer 23

hyperparathyroidism and hypercalcaemia

Question 24

side effect of ECT

Answer 24

cardiac arrhythmias

Question 25

how do you treat mania/hypomania is patients are on an antidepressant medication

Answer 25

stop the antidepressant start an antispsychotic

Question 26

how do you treat mania/hypomania is patients are on an antidepressant medication

Answer 26

stop the antidepressant start an antipsychotic

Question 27

MOA of benzodiazepines

Answer 27

increase the effect of GABA

Question 28

assessment score for the severity of alcohol withdrawal

Answer 28

revised clinical institute withdrawal assessment for alcohol (CIWA)

Question 29

how can korsakoff present

Answer 29

CN6 palsy

Question 30

timings in alcohol withdrawal

Answer 30

symptoms in 6-12 hours seizures in 36 hours delirium tremens in 72 hours

Question 31

MOA of disulfiram

Answer 31

alcohol deterrent causing vomiting

Question 32

MOA of acamprosate

Answer 32

alcohol anti-craving medication

Question 33

MOA of buprenorphine

Answer 33

patient comes off methadone to tablet under the tongue

Question 34

how long do patients need depressive sx for according to ICD10

Answer 34

2 weeks

Question 35

biomarkers in anorexia

Answer 35

most things reduce G and C increase

Question 36

3 symptoms in PTSD

Answer 36

re-experiencing (flashbacks, nightmares) avoidance (people or situations) hyperarousal (hypervigilance, sleep problems)

Question 37

personality disorder with a fear of criticism

Answer 37

avoidant

Question 38

personality disorder treated with DBT

Answer 38

borderline

Question 39

personality disorder diagnosed mainly in men

Answer 39

antisocial

Question 40

personality disorder with the negative symptoms of schizophrenia

Answer 40

schizoid

Question 41

define erotomania (de clerambault's)

Answer 41

delusion that a famous person is in love with them

Question 42

define knight's move thinking

Answer 42

illogical leaps between ideas

Question 43

define flight of ideas

Answer 43

discernible links between ideas

Question 44

physical symptoms for 2 years pt refuses negative results

Answer 44

somatisation disorder

Question 45

persistent belief in an underlying serious illness

Answer 45

hypochondriasis (illness anxiety disorder)

Question 46

loss of motor or sensory function due to stress

Answer 46

conversion disorder

Question 47

intentional production of symptoms

Answer 47

munchausen's (factitious)

Question 48

exaggeration of symptoms for financial gain

Answer 48

malingering