Psychiatry Flashcards

1
Q

give 2 examples of typical antipsychotics

A

haloperidol
chlorpromazine

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2
Q

give 4 examples of atypical antipsychotics

A

clozapine
risperidone
olanzapine
aripiprazole

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3
Q

MOA of typical antipsychotics

A

D2 receptor antagonists (block dopamine)

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4
Q

MOA of atypical antipsychotics

A

act on dopamine and HT

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5
Q

major side effect differences between typical and atypical antipsychotics

A

typical: extrapyramidal and increase prolactin levels
atypical: metabolic and weight gain

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6
Q

which antipsychotic causes life threatening agranulocytosis and neutropenia
what do you monitor

A

clozapine

FBC for leukocytes

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7
Q

give 4 examples of extrapyramidal side effects in antipsychotics

A

parkinsonism (bilateral resting tremor)
acute dystonia (muscle contraction causing torcollis)
akathisia (restlessness)
tardive dyskinesia (involuntary movements - chewing, pouting, blinking)

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8
Q

which antipsychotic has the least effects on prolactin

A

aripiprazole

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9
Q

medication to manage torcollis

A

procyclidine

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10
Q

medication to manage tardive dyskinesia

A

tetrabenazine

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11
Q

name some other side effects of antipsychotics

A

stroke/VTE
sedation
seizures
increased QT
sedation
galactorrhoea
antimuscarinic
neuroleptic malignant syndrome
reduced glucose tolerance
weight gain

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12
Q

4 antimuscarinic side effects

A

dry mouth
blurred vision
constipation
urinary incontinence

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13
Q

which antipsychotic increased the QT interval the most

A

haloperidol

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14
Q

pyrexia and muscle stiffness on antipsychotic

A

neuroleptic malignant syndrome

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15
Q

main side effect and management of SSRI

A

GI disturbance
give PPI

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16
Q

which side effect does citalopram cause

A

prolonged QT interval
torsades de pointes

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17
Q

which medication do SSRIs interact with to cause serotonin syndrome

A

MAOis

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18
Q

dizziness, shock and anxiety on SSRI

A

discontinuation

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19
Q

effect of using SSRIs during the third trimester

A

persistent pulmonary hypertension of the newborn

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20
Q

which SSRI do you give post MI

A

sertraline

21
Q

which medication should you avoid whilst on SSRIs

A

triptans

22
Q

when are samples for lithium levels taken

A

12 hours post dose

23
Q

2 side effects of long term lithium use

A

hyperparathyroidism and hypercalcaemia

24
Q

side effect of ECT

A

cardiac arrhythmias

25
Q

how do you treat mania/hypomania is patients are on an antidepressant medication

A

stop the antidepressant
start an antispsychotic

26
Q

how do you treat mania/hypomania is patients are on an antidepressant medication

A

stop the antidepressant
start an antipsychotic

27
Q

MOA of benzodiazepines

A

increase the effect of GABA

28
Q

assessment score for the severity of alcohol withdrawal

A

revised clinical institute withdrawal assessment for alcohol (CIWA)

29
Q

how can korsakoff present

A

CN6 palsy

30
Q

timings in alcohol withdrawal

A

symptoms in 6-12 hours
seizures in 36 hours
delirium tremens in 72 hours

31
Q

MOA of disulfiram

A

alcohol deterrent causing vomiting

32
Q

MOA of acamprosate

A

alcohol anti-craving medication

33
Q

MOA of buprenorphine

A

patient comes off methadone to tablet under the tongue

34
Q

how long do patients need depressive sx for according to ICD10

A

2 weeks

35
Q

biomarkers in anorexia

A

most things reduce
G and C increase

36
Q

3 symptoms in PTSD

A

re-experiencing (flashbacks, nightmares)
avoidance (people or situations)
hyperarousal (hypervigilance, sleep problems)

37
Q

personality disorder with a fear of criticism

A

avoidant

38
Q

personality disorder treated with DBT

A

borderline

39
Q

personality disorder diagnosed mainly in men

A

antisocial

40
Q

personality disorder with the negative symptoms of schizophrenia

A

schizoid

41
Q

define erotomania (de clerambault’s)

A

delusion that a famous person is in love with them

42
Q

define knight’s move thinking

A

illogical leaps between ideas

43
Q

define flight of ideas

A

discernible links between ideas

44
Q

physical symptoms for 2 years
pt refuses negative results

A

somatisation disorder

45
Q

persistent belief in an underlying serious illness

A

hypochondriasis (illness anxiety disorder)

46
Q

loss of motor or sensory function due to stress

A

conversion disorder

47
Q

intentional production of symptoms

A

munchausen’s (factitious)

48
Q

exaggeration of symptoms for financial gain

A

malingering