psychiatric genetics Flashcards
proportion of variance in a condition is by genetic factors
heritability
amount of difference in who develops a trait or does not from genetic factors
population-level estimate
genetic profile or make up
1 percent varies between people
genotype
observable characteristics of genetic variabiliity
genotype plus environment
phenotype
measurable characteristics that indicate vulnerability to manifest a disorder
biomarker
a special type of biomarker that is present even when the disorder is not present
endophenotype
ACE (heritable, common environment, not common environment)
how much variability in a trait is due to biological factors
behavior genetics
risk-conferring genes
how much variability is due to specific gene variant
molecular genetics
gene and environment interactions and correlations mathematically assumed to be genetic
equal environments assumption
substantial portion of behavior influenced by nonshared environment
the gloomy prospect effect
Molecular genetics
what genes are responsible
identifies target genes and look for association with disorder
candidate gene studies
look for association with the disorder with no target gene necessary
genome-wide association studies