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pance > Psych Meds > Flashcards

Psych Meds Flashcards

1
Q

Mood Stablizers

A
  • Lithium (1st line)
  • Divalproex (Depakote)
  • Carbamazepine (Tegretol)
  • Lamotrigine (Lamictal)
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2
Q

Lithium SEs

A
  • Hypothyroidism**
  • Increased urination & thirst
  • DI

**narrow therapeutic index = toxicity!

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3
Q

Lamotrigine (Lamictal) SEs

A

-rash, SJS

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4
Q

Lamotrigine Black Box Warning

A

Do NOT use in <16 yo

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5
Q

“Typical” 1st Generation Antipsychotics

A
  • Butyrophenones

- Phenothiazines

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6
Q

Butyrophenone Medications

A
    • “Typical” 1st Generation Antipsychotics
  • Haloperidol (Haldol)
  • Droperidol
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7
Q

Phenothiazine Medications

A
    • “Typical” 1st Generation Antipsychotics
  • Chlorpromazine (Thorazine)
  • Fluphenazine
  • Promethazine (Phenergan)
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8
Q

“Typical” 1st Generation Antipsychotics MOA

A

Blocks CNS dopamine receptors (dopamine antagonists)

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9
Q

“Typical” 1st Generation Antipsychotics SEs

A

-EPS sx: rigidity, tremor, akathisia (restlessness)

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10
Q

What class of antipsychotics has a greater risk of EPS?

A

“Typical” 1st Generation Antipsychotics

Haloperidol**, Chlorpromazine, Fluphenazine, Promethazine

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11
Q

Dystonic Reaction (Dyskinesia)

A
  • EPS syndrome

- Hours-days after initiation of “Typical” 1st Generation Antipsychotics

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12
Q

Dystonic Reaction (Dyskinesia) Symptoms

A
  • Tongue protrusion
  • Facial grimacing
  • Torticollis
  • Difficulty speaking
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13
Q

Treatment of Dystonic Reaction (Dyskinesia)

A

-IV Diphenhydramine OR anticholinergic agent (Benztropine)

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14
Q

Tardive Dyskinesia

A
  • EPS syndrome

- Seen with LONG-TERM use

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15
Q

Tardive Dyskinesia Symptoms

A
  • Lip smacking
  • Teeth grinding
  • Rolling of tongue
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16
Q

Chlorpromazine (Thorazine) PEARLS

A
  • anticholinergic - DRY MOUTH
  • **causes sedation!
  • Used mostly as antiemetic
17
Q

“Atypical” 2nd Generation Antipsychotics

A
  • Clozapine (Clozaril)
  • Quetiapine (Seroquel)
  • Olanzapine (Zyprexa)
  • Risperidone(Risperdal)
  • Ariraprazole (Abilify)
18
Q

“Atypical” 2nd Generation Antipsychotics MOA

A

Blocks CNS dopamine receptors (dopamine antagonists) AND serotonin (5HT2) receptors

19
Q

“Atypical” 2nd Generation Antipsychotics Indication

A

1st line for psychotic D/O’s!

20
Q

Clozapine (Clozaril) Caution

A
  • *Agranulocytosis! = monitor CBC weekly
  • weight gain
  • *Only used in pts resistant to other psych meds!
21
Q

Olanzapine (Zyprexa) SEs

A

**DM & weight gain!

22
Q

Risperidone (Risperdal) SEs

A

**increased prolactin!

23
Q

Serotonin Syndrome

A
  • SSRI used in combo with MAOI (wash out period)

- restlessness, agitation, diaphoresis, tremor, N/V, mydriasis (dilation)

24
Q

Neuroleptic Malignant Syndrome

A
  • a/w 1st gen antipsychotics
  • d/t dopamine inhibition
  • EXTREME MUSCLE RIGIDITY, tremor, tachy, fever*
  • MC after dose increase

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