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Psych Meds Flashcards

1
Q

Ritalin

A

methylphenidate

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2
Q

Adderall

A

Dextroamphetamine

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3
Q

Ambien

A

Zolpidem

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4
Q

What is the mechanism of Ambien

A

Interacts with the GABA-Benzodiazepine receptor

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5
Q

Concerta

A

Methylphenidate

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6
Q

Vyvanse

A

Lisdexamfetamine

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7
Q

BuSpar

A

Buspirone

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8
Q

When is Buproprion Contraindicated

A

Patients with seizures`

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9
Q

Can BuSpar be used as an adjunct therapy for anxiety

A

You bet’ya

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10
Q

What other beneficial effects does buspar have in the treatment of anxiety and depression

A

Tends to have a stimulative effect which helps combat the neurovegetative state

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11
Q

Cymbalta

A

Duloxetine

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12
Q

Klonopin

A

Clonazepam

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13
Q

What is the half life of action of klonopin

A

20-50 hours

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14
Q

Remeron

A

Mirtazipine

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15
Q

What is the mechanism of Remeron

A

Antagonizes alpha-2 adrenergic and serotonin 5HT-2 receptors

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16
Q

Effexor

A

Venlafaxine

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17
Q

Pristiq

A

Desvenlafaxine

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18
Q

What is the mechanism of Desvenlafaxine

A

SNRI

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19
Q

What is desvenlafaxine used to treat

A

Major Depressive Disorder

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20
Q

Strattera

A

Atomoxetine

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21
Q

What is atomoxetine used to treat

A

ADHD

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22
Q

What is the mechanism of atomoxetine

A

Selectively inhibits Norepinephrine reuptake

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23
Q

Abilify

A

Aripiprazole

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24
Q

What is aripiprazole

A

2nd generation antipsychotic

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25
Q

Ativan

A

Lorazepam

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26
Q

Aricept

A

Donepezil

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27
Q

What is the mechanism of Donepezil

A

Cholinesterase inhibitor

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28
Q

What is donepezil used to treat

A

Dementia

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29
Q

Namenda

A

Memantine

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30
Q

What is the mechanism of memantine

A

NMDA receptor Antagonist

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31
Q

Fioricept

A

Butabital / acetaminophen / caffeine

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32
Q

Flexeril

A

cyclobenzaprine

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33
Q

How is lithium used for depression?

A

As an adjunct to therapy. It will also help alleviate the compulsions.

34
Q

What is the benefit of adding Abilify to pristiq

A

It improves the treatment of depression and helps control insomnia

35
Q

Campral

A

Acamprosate

36
Q

What is acamprosate used to treat

A

Alcohol dependence

37
Q

What is the mechanism of acamprosate

A

effects the GABA receptors

38
Q

Relpax

A

Eletriptan

39
Q

What is eletriptan used to treat

A

Miagraine HA

40
Q

What is the mechanism of Eletriptan

A

Activates the vascular 5HT-1 Receptors that cause vasoconstriction.

41
Q

What is the mechanism of Viibryd

A
  • SSRI

- Selectively inhibits serotonin reuptake and partially agonizes serotonin 5HT-1A receptors.

42
Q

Amitiza

A

Lubiprostone

43
Q

What is lubiprostone used to treat

A

Constipation predominant IBS

44
Q

What is the mechanism of Lubiprostone?

A

activates ClC-2 chloride channels, increasing intestinal fluid secretion and motility (osmotic laxative)

45
Q

What are the indications of a dopamine blockade

A

It will cause in an increase in prolactin leading to galactorhea, impotence, menstrual dysfunction and decreased libido

46
Q

What is the side effect of thioridazine

A

causes retinal pigment deposits

47
Q

What are the major side effects of clozapine

A 
agranulocytosis
orthostatic hypotension
weight gain
metabolic syndrome
sedation
constipation
48
Q

What are the major side effects of chlorpromazine

A

jaundice and photosensitivity

49
Q

What are the major side effects of Olanzapine

A

weight gain,
sedation,
hypotension
dry mouth

50
Q

What are the major side effects of Quitiapine

A 
Sedation, 
orthostatic hypotension, 
akathisia, 
weight gain, 
dry mouth
51
Q

What are the major side effects of Ziprasidone

A

Nausea
weakness
mild QT prolongation

52
Q

What are the major side effects of aripiprazole

A 
headache
nausea
akathisia
tremor 
constipation`
53
Q

What are the major side effects of Paliperidone

A 
pakinsonism
dystonia
dyskinesia
akathisia
QT prolongation
54
Q

Side effects of Topamax

A

Skinny and Stupid

55
Q

What receptors are affected by antipsychotics

A 
Also knows as neuroleptics
block various receptors including:
cholinergic 
adrenergic
sertoninergic
muscarinic
histamine
56
Q

What is the mechanism of action of the antipsychotics

A

blocking of dopamine receptors in the CNS, particular the D2 receptors in the mesocortical and mesolimbical systems of the brain

57
Q

How does the potency of the antipsychotics differ

A

They differ in their affinity for the D2 receptor in the brain:
Haloperidol - high affinity/potency
Chlorpromazine - low affinity/potency

58
Q

What is the onset of action for antipsychotics

A

may not become effective for several weeks to months. However, sedation and other side effects can occur rapidly

59
Q

Can antipsychotics cure schizophrenia

A

Nope, but it can treat the symptoms

60
Q

Name the phenothaizines

A 
chlorpromazine (thorazine)
Fluphenazine (prolixin)
Trifluoperazine (stelazine)
Thioridazine (Mellaril)
Perphenazine (Trilafon)
61
Q

What distinctive side effects does thioridazine cause

A

Pigmentary retinopathy.

May cause cardiac arrhythmias and conduction block

62
Q

Name the Butyrophones

A

Haloperidol (Haldol)

Droperidol (Inapsine)

63
Q

Other than psychotic states, what can haloperidol be used

A

Tourettes syndrome
Huntingtons disease
Phencyclidine overdoes

64
Q

Name the classes of the traditional antipsychotics

A

Phenothiazines
Butyrophenones
Dibenzoxazepines
Thioxanthenes

65
Q

Name a drug that belongs to the dibenzoxazepines

A

loxapine (Loxitane)

66
Q

Name a drug that belongs to the thioxanthenes

A

Thioxanthene (Navane)

67
Q

What are the clinical applications of traditional antipsychotic agents

A
  1. Treatment of any agitated or psychotic state (bipolar or schizophrenia)
  2. Antiemetic therapy (phenothiazines except thioridazine)
  3. Treatment of Tourettes syndrome (haloperidol)
  4. Treatment of intractable hiccups (chlorpromazine)
  5. Antipruritic therapy (promethazine)
68
Q

How do the side effects vary with the different antipyschotics

A

The greater the affinity to the D2 receptor the greater the degree of side effect

69
Q

What are the endocrine alterations associated with Antipsychotics

A

Galactorhea,
amenorrhea,
infertility,
all likely due to blockade of dopamine release from the pituitary

70
Q

What are the Anticholinergic effects associated with antipsychotics

A

Dry mouth
constipation
urinary retention
blurry vision

71
Q

What are the antiadrenergic effects associated with antipsychotics

A

light-headedness and orthostatic hypotension secondary to a-adrenergic blockade

72
Q

What are the extrapyramidal side effects associated with antipsychotics

A

Akathisia (motor reslessness),
parkinsonian syndrome (bradykinic rigidity)
Neuroleptic malignant syndrome
Tardive dyskinesia

73
Q

Zyprexa

A

Olanzapine

74
Q

What is olanzapine

A

2nd generation antipsychotic

75
Q

Trileptal

A

Oxcarbazepine

76
Q

What is the mechanism of Oxcarbazepine

A

Blocks voltage sensitive Na channels

77
Q

What is oxcarbazepine indicated for

A

Seizures

Bipolar

78
Q

Depakote

A

Divalproex sodium

79
Q

What is divalproex sodium indicated to treat

A

Seizures
Bipolar
Migraine prophylaxis

80
Q

What is the mechanism of Divalproex sodium

A

Increases GABA effects

May inhibit glutamate/NMDA receptor-mediated neuronal excitation

81
Q

Geodon

A

ziprasidone

82
Q

Invega

A

paliperidone

Med School Rotations (26 decks)

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