Psych drugs

Question 1

Tramadol + SSRI

Answer 1

Serotonin syndrome - Cognitive - headache, confusion, hallucination
sAutonomic - shivering, sweating, vasoconstriction
Somatic - myoclonus, hyperreflexia, tremor

Question 2

Dementia of Alzheimers Type

Slow the decline

Answer 2

Cholinesterase inhibitors (e.g. Donezepil)

Question 3

Alzheimers Mild MMSE

Answer 3

20-24

Question 4

AlzheimersModerate MMSE

Answer 4

13-20

Question 5

AlzheimersSevere MMSE

Answer 5

<12

Question 6

Dementia with Lewy Bodies

Management

Answer 6

Benzodiazepines (behavioural disturbances)
Anticholinergics (Parkinsonisms)
Risperidone or Olanzapine for psychosis - DO NOT GIVE TYPICAL ANTIPSYCHOTICS

Question 7

Typical antipsychotics

Answer 7

Chlorpromazine, Haloperidol, Zuclopenthixol

Question 8

Typical antipsychotic Side effects

Answer 8

EPSEs, elevated prolactin, neuroleptic malignant syndrome, prolonged QT, arrhythmias

Question 9

ChlorpromazineS/E

Answer 9

Increases sun sensitivity

Question 10

Zuclopenthixol

Answer 10

Depot

Question 11

Atypical antipsychotics

Answer 11

Olanzapine, seroquel (quetiapine), risperidone, clozpine

Question 12

Atypical antipsychoticsSide effects

Answer 12

Fewer EPSEs, increased risk of CVA, metabolic side effects

Question 13

Olanzapine S/E

Answer 13

Weight gainDiabetes

Question 14

Quetiapine (Seroquel) S/E

Answer 14

SedativeEPSE

Question 15

Risperidone S/E

Answer 15

Pain at injection site
Lactation
Less metabolic effects than other atypicals

Question 16

ClozapineS/E

Answer 16

Neutropaenia, agranulocytosis, myocarditis, diabetes, weight gain, HTN, hepatitis, piaprism
ONLY IN TREATMENT RESISTANT SCHIZOPHRENIA OR RECURRENT SUICIDAL IDEATION

Question 17

SSRI

Answer 17

Citalopram
Escitalopram
Fluoxetine
Sertraline

Question 18

SSRIS/E

Answer 18

Headache, nausea, vomiting, sexual dysfunction

Question 19

Citalopram S/E

Answer 19

Prolonged QT

Question 20

Escitalopram

Answer 20

Used in PND

S/E: hypokalaemia

Question 21

SSNR

Answer 21

Venlafaxine

Question 22

TCA

Answer 22

Amitriptyline, clompiramine, mirtazapine

Question 23

TCA S/E

Answer 23

anti-SLUD, sedation, weight gain, orthostatic hypotention, sinus tachycardia, death in OD, prolonged QT, T wave inversion

Question 24

MirtazapineS/E

Answer 24

Increased appetiteWeight gainAgranulocytosis

Question 25

Irreversible MAO inhibitorsS/E

Answer 25

Hard cheese effect - hypertensive crisis due to reaction with tyramine in cheese

Question 26

LithiumS/E

Answer 26

Hypothyroidism, epigastric discomfort, weight gain, vertigo, tremor, acne, psoriasis, leukocytosis, polyuria, benign T wave changes, nephrotoxicity

Question 27

Parkinson’s Treatment

Answer 27

L-dopa and carbidopa
Dopamine agonists
Anti-cholinergics (Benztropine)