Psych Disorders, Schizophrenia Flashcards

1
Q

Psychosis

A

-Thought disorder which reality is Grossly impaired
-May be evidenced by symptoms of hallucinations delusions, disorganized thinking, disorganization of personality, deterioration of reality and bizarre behaviors
-Can be a sole diagnosis (NOS)

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2
Q

Hallucination

A

Alterations to the sensory system (5 senses)
-Command hallucinations can be harmful

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3
Q

Delusion

A

Alterations to their thought process

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4
Q

Biological factors contributing to schizophrenias

A

-Genetic
-Psychological
-Environmental
-Brain structure abnormalities (Holes in the brain)
-Neurobiological

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5
Q

Genetic contributions to Schizophrenia

A

-50% risk if both parents have it
-Sibling puts you at a 10% risk

-Essentially there is a strong genetic component in schizophrenia

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6
Q

Differences in sex and schizophrenia

A

-Male: Earlier onset (18-25 yrs), With More structural differences, prevalent Negative symptoms
-Female: Later onset (25-35yrs) with less structural differences, leading to better outcomes. Rare that symptoms occur before 19

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7
Q

Stigma of psych disorders

A

-Struggles to get insurance coverage
-Substance abuse, high prevalence of substance use (Self medication), complicates diagnosis and medications (Interactions with meds)
-A majority of people with schizophrenia smoke nicotine

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8
Q

Losses that occur with schizophrenia

A

-Schizophrenia is diagnosed usually after 18, and you can lose alot of your life with it

-Such as your role and routines, former friends/relationships, sense of self, Sense of belonging in society

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9
Q

Psych disorders

A

-Delusional disorder
-Brief psych disorder (Only for like a day)
-Schizophreniform disorder: similar to schizophrenia but its duration is usually 1-6 mo when schizophrenia is 6 mo+
-Schizoaffective disorder: Schizophrenia + Mania, hard to treat
-Substance/medication induced psychotic disorder

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10
Q

Comorbidities with psych disorders

A

-Substance use disorders
-Anxiety
-Depression
-Suicide: High prevalence of attempts and successes
-Psych polydipsia: Drink so much it causes severe hyponatremia

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11
Q

Medical conditions that can cause acute psychosis

A

-Alc withdrawal
-Huntington’s disease
-Hypo/hyper thyroidism
-Hypoglycemia
-Ca imbalances
-Temporal lobe epilepsy
-Wilson’s disease
-CNS neoplasms
-Encephalitis
-Meningitis
-Neurosyphilis (Stage 3 goes to brain)
-Stroke
-Hepatic encephalopathy
-DKA
-Vitamin B-12

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12
Q

Course of the disorder, schizophrenia

A

-Prodromal
-Acute psychosis
-Residual stage

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13
Q

Schizophrenia course: Prodromal

A

Stage of early change, precursor to the disorder
-Can begin in childhood
-Early recognition, early treatment

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14
Q

Schizophrenia course: Active Psychosis

A

-Acute psychotic phase
-Can be hospitalized
-Hallucinations and delusions
-Aggressive treatment find out the cause

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15
Q

Schizophrenia course: Residual

A

-Post acute psychosis
-Decrease in positive signs (Hallucination/delusions)
-More negative symptoms remain (Flat affect, impaired role functioning)
-Residual impairment increases after each episode of psychosis (It becomes harder and harder to bounce back to what you were)

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16
Q

Schizophrenia prognosis

A

-Difficult to predict
-Uncommon for people to return to full functioning
-Identify factors that lead to positive outcomes

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17
Q

Factors that lead to positive outcomes schizophrenia

A

-Early recognition (Early treatment)
-Female gender (Less brain degeneration)
-Abrupt onset of symptoms with obvious precipitating factors
-Rapid resolution of active phase symptoms
-Absence of structural brain abnormalities
-Normal neuro functioning
-No family history of schizophrenia

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18
Q

Factors that lead to negative outcomes schizophrenia

A

-Chronic medical conditions
-Substance abuse
-Stress
-Frequency and intensity of episodes (Long and often)
-Social deficits

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19
Q

Schizophrenia and suicide

A

They commit at high rates, comorbid mental disorders, younger people are more likely, Females are more likely

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20
Q

Schizophrenia symptoms: Related to speech

A

-Echolalia
-Circumstantiality
-Word salad
-Neologism
-Clang association
-Metonymic speech
-Stilted language
-Pressured speech

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21
Q

Echoloalia

A

-repetition of another person’s for no reason

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22
Q

Circumstantiality

A

Can’t stay on track, gives useless details before arriving at the point

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23
Q

Word salad

A

They say words in a sentence in a random order in a sentence that doesnt make sense

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24
Q

Neologism

A

Making up words that only have meaning to them

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25
Q

Clang association

A

Rhyming words for no reason

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26
Q

Metonymic speech

A

Using words with similar meanings interchangeably

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27
Q

Stilted language

A

Words that are excessively formal, stilted as in high up and fancy

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28
Q

Pressured speech

A

Speaking so fast, not letting you get a word in

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29
Q

Interventions for alterations in speech

A

-Explain how their behavior can disturb others
-Anticipate their needs
-Orientate them to reality, call them by their name
-Be concrete in speech (direct)
-Avoid abstractions,phrases, cliche jokes

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30
Q

Schizophrenia: Alterations in thinking

A

-Loose associations
-Tangentiality
-Flight of ideas
-Paranoia
-Referential
-Autistic thinking
-Concrete
-Verbigeration

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31
Q

Loose associations

A

Cant connect the dots between things

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32
Q

Tangentiality

A

Perpetual tangent
-Mind doesnt let them get to the point

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33
Q

Flight of ideas

A

-Spitballing
-Babbling

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34
Q

Paranoia

A

Thinks there might be people after them
Irrational fear

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35
Q

Referential

A

-Feels like something that doesnt affect them at all is being directed at them
-Watching the news and thinks they are speaking directly to them

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36
Q

Autistic thinking/ Concrete

A

-Very literal
-Black and white
-Cant understand metaphors

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37
Q

Verbigeration

A

Repetition of words that don’t serve a purpose

-Example: dog cat ate car work

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38
Q

Schizophrenia symptoms, Alterations in perception

A

-DePersonalization
-Hallucinations: Perception with no external stimuli
-Illusions
-Derealization

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39
Q

Depersonalization

A

-Loss of self or identity

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40
Q

-Illusions

A

Misinterpretation of real experience

41
Q

Derealization

A

False perception environment has changed

42
Q

Schizophrenia symptoms: Alterations in behaviors 1

A

-Bizarre behavior stupor
-Stereotyped behavior
-Automatic obedience
-Waxy flexibility
-Extreme motor agitation
-Negativism
-Lack of impulse control

43
Q

Waxy flexibility

A

-It you put the pt in a position, like stick their arm up, they will believe they are unable to move it, even if the are physically capable
-Kinda ties into the automatic obedience

44
Q

Lack of impulse control

A

May result in agitated behaviors such as the pt abruptly taking the TV remote and changing channels
-Stealing the remote or something

45
Q

Schizophrenia symptoms: Alterations in behaviors 2

A

-Aggression
-Agitation
-Catatonia
-Catatonic excitement
-Echopraxia
-Regressed behavior
-Stereotypy
-Hypervigilance

46
Q

Catatonia

A

-Disruption of a person’s awareness to the world around them, described as being in a stupor

47
Q

Catatonic Excitement

A

-Prolonged periods of psychomotor agitation
-Purposeless movements
-Grimacing

48
Q

Echopraxia

A

Involuntary copying of someone else behavior

49
Q

Hypervigilance

A

Expecting something to go down at any time even with no indication

50
Q

Types of delusions

A

-Persecution
-Ideas of reference
-Grandiose
-Erotomaniac
-Somatic
-Thought insertion
-Thought broadcasting
-Delusions of being controlled
-Nihilistic delusion
-Paranoia
-Magical thinking

51
Q

Types of delusions: Persecution

A

Someone is after you

52
Q

Types of delusions Ideas of reference

A

Making a trivial event that doesnt really affect you into a huge deal all about you

53
Q

Types of delusions: Grandiose

A

Feeling as if they are special, having powers, wealthy or identity

54
Q

Types of delusions: Erotomaniac

A

Everyone loves you and wants to get with you

55
Q

Types of delusions: Somatic

A

Believes they are experiencing a medical condition, when its really in their head
-Example is they believe they have TMJ but its just a delusion

56
Q

Types of delusions: Thought insertion

A

Aliens are in their head

57
Q

Types of delusions: Thought broadcasting

A

-Their thoughts can be heard by someone else
-Thinks you are reading their mind

58
Q

Types of delusions: Delusions of being controlled

A

Feels like they are being controlled by another entity

59
Q

Types of delusions: Nihilistic delusion

A

-Feels like they are invisible, not human, or dead

60
Q

Types of delusions: Magical thinking

A

Think they have control over the situation

61
Q

Interventions for delusions

A

-Never argue or agree with delusions
-Acknowledge feelings
-Respond calm and matter fact
- ** Dont touch a paranoid person (or generally dont touch people) **
-Be aware of your verbal and non verbal gestures
-Be honest
-Take a neutral stance and change topic to something neutral
-Interject doubt when appropriate, don’t interrupt them
-Observe events that Trigger delusions
-Distract them from delusions and focus on reality

62
Q

Negative symptoms of Schizophrenia

A

Negative symptoms mean taking away, or they are less than the normal

-Diminished emotions (Blunted affect)
-Avolition (Lack of motivation)
-Alogia (Dont speak much)
-Anhedonia
-Asociality

63
Q

Positive symptoms of schizophrenia

A

-Hallucinations
-Delusions
(Disorganized speech, Bizarre behaviors)

More receptive to meds

64
Q

Types of hallucinations

A

False sensory perceptions that are not involved with any external stimuli
-Auditory
-Visual
-OlFactory
-Gustatory
-Tactile

65
Q

Command Hallucinations

A

Can indicate a psych emergency (risk of suicide or harming others)
-May be at risk of violence
-Must be assessed
-Can be terrifying for the individual
-Can have multiple voices with personalities and gender
-Can be at greater risk if you give identity to the voice

66
Q

Interventions for hallucinations

A

-Ask pt what they are seeing, reorientate as much as possible
-Assess for command hallucinations: ask directly are the voices telling you to hurt yourself or others
-never react to the hallucinations as if they are real
-Observe S+S that the pt might be hallucinating
-Offer support without being negative to the pt
-Dont touch the pt
-Distraction from the hallucination
-Be aware of the increasing anxiety of the pt
-Be Calm
-Assess suicide risk
-Low stim environment
-Observe behaviors frequently

67
Q

Hallucination assessment

A

-Is it substance induced
-Command hallucinations
-Belief system (Need cultural considerations)
-Co-occurring disorders
-Current meds, adherence?
-Family understanding
-Support systems

68
Q

Treatment/ team and community approach

A

-Therapy, group allegiance
-Social skills training
-Behavioral therapy, family therapy
-Psych meds
-Health teaching
-Mileu
-INstill hope
-Social support
-Have collaboration between Primary and Psych team

** family needs to be included**

69
Q

Antipsychotic meds

A

-Help with symptoms of schizophrenia but do NOT cure
-Psych symptoms return with med non-adherance

70
Q

Antipsych meds are effective in

A

-Acute exacerbation of schizophrenia
-Preventing or mitigating a relapse

71
Q

First gen antipsych meds target

A

-Positive symptoms only
-Lots of EPS

72
Q

Second gen antipsych meds target

A

Positive and negative symptoms
-Have fewer motor side effects
-Treat anxiety depression and decrease suicidal behavior

73
Q

Typical antipsych MOA

A

Blocking postsynaptic dopamine receptors in the basal ganglia, hypothalamus, limbic system , brainstem and medulla
-More dopamine available

Also high affinity for cholinergic, alpha 1 adrenergic and histamine
-Sedative effects

74
Q

Minimize anticholinergic effect of antipsych

A

-Chew sugarless gum, food high in fiber, eat and drink 2-3 L a day

75
Q

Postural hypotension and antipsych

A

High incidence, need to get up and down slowly to minimize the effects

76
Q

Adverse effects of antipsych drugs

A

Main thing is the postural hypotension
-Anticholinergic effects
-EPS

77
Q

Typical antipsych, drugs

A

-Haloperidol (Haldol)
-Chlorpromazine (Thorazine)
-Fluphenazine (Prolixin)

78
Q

Extrapyramidal symptoms (EPS)

A

-Caused by dopamine blockage

-Acute dystonia
-Pseudo parkinsonism
-Akathisia
-Tardive dyskinesia

79
Q

EPS: Acute dystonia

A

-Painful muscle spasms of tongue jaw, face or neck
-Scary for pt
-Quick onset, hours to days after taking antipsych
-More often in young males
Includes opisthotonos , oculogyric crisis, torticollis

80
Q

Opisthotonos

A

-Tetanic spasm which head and heels are bent back and the body forwards
-Symptom of acute dystonia

81
Q

Oculogyric crisis

A

Eyes are fixed upwards
-Symptom of acute dystonia

82
Q

Torticollis

A

Spasm of the neck which forces the head to one side, and the chin is pointed to opposite side

83
Q

Acute dystonia mgmt

A

Benadryl 25-50 mg stat, instant relief

84
Q

EPS: Pseudo parkinsonism

A

-All the symptoms of parkinson, Pill rolling, mask face, shuffling gait
-Slowed down (Bradykinesia)
-Cogwheeling
-Appears early into drug therapy
-Too little dopamine and too much Ach
-Tremors

85
Q

Pseudo parkinsonism mgmt

A

-Anticholinergics like Artane or cogentin or dopamine agonist, or lower dose of antipsych

86
Q

EPS: Akathisia

A

-Inner restlessness, or inability to sit still. Compulsion to walk
-Feels distressful, not in their control
-Schizophrenia symptom as well as drug

87
Q

Akathisia mgmt

A

-Propranolol or ativan
-May need finger foods

88
Q

EPS: Tardive dyskinesia

A

-Occurs after prolonged treatment
-Irreversible if not caught early

-Involuntary muscle spasms (Tongue, mouth, fingers, toes, pelvis. trunk)
-Affects 1/2 of people in long term anti psych meds
-AIMS scale for worsening symptoms
-Anticholinergics can make it worse

89
Q

Early signs and symptoms of tardive dyskinesia

A

-Lip smacking and tongue movements

90
Q

Mgmt of EPS

A

-Catch it early to minimize
Treatment includes
-Lowering the dose
-Giving parkinson’s drugs (Anticholinergics)
-Only 2 at a time, too many drugs can make TD worse

91
Q

Med mgmt of EPS

A

-Trihexyphenidyl (Artane)
-Benztropine Mesylate (Cogentin)
-Diphenhydramine hydrochloride (Benadryl)
-Amantadine hydrochloride (Symmetrel)

92
Q

Atypical antipsychotics

A

-Risperidone (Risperdal)
-Quetiapine (Seroquel)
-Olanzapine (Zyprexa)
-Zapine (Zyprexa)
-Clozapine (Clozaril)
-Paliperidone (Invega)
Ziprasidone (Geodon)

93
Q

Only third generation antipsych

A

Aripiprazole (Abilify)

94
Q

Clozapine

A

-Clozaril (Brand name)
-Used in more treatment resistant cases
-Not first line due to severe adverse reactions
-Agranulocytosis
Severe reduction in WBC count, neutropenia
Rare but fatal
S+S are a sore throat fever malaise and mouth sores
Any flu like S+S should be reported to the provider

95
Q

Benefits of second gen (Atypical) antipsych

A

-Fewer SE, better tolerated
-Helps with negative symptoms
-Decreases Suicidal ideation
-Improves neurocognitive functioning
-May cause weight gain tho
Minimal EPS

96
Q

Negative of Second gen (Atypical ) antipsychotics

A

-May cause weight gain due to abnormal metabolism of glucose
-Anticholinergic SE
-Monitor weight, BMI, Glucose (Metabolic syndrome)
-Sexual dysfunction
-Very expensive

97
Q

Metabolic syndrome

A

-Associated with atypical anti psych with metabolic disruption
-Need 3/5

-Weight gain
-Type 2 diabetes
-Increased LDL
-Decreased HDL
-Elevated triglycerides

Can lead to DKA

98
Q

Neuroleptic Malignant Syndrome

A

-Rare medical emergency with Atypical anti psych
-Possibly caused by a acute reduction in DA

S+S
-Hyperthermia
-Muscle rigidity
-Tremors
-Fluctuating BP
-Altered consciousness

99
Q

Antipsych meds education

A

-Dont drive when drowsy
-Dont abruptly discontinue, you can have withdrawal
-Photosensitivity
-Get blood work if needed
-Report flu like symptoms, Unusual bleeding, bruising, N+V, HA, rapid HR, difficulty urinating, muscle twitching or tremors, dark urine, excessive urination, polyphagia polyphagia, jaundice, skin rash
-Orthostatic hypotension precautions
-Sugarless gum for anticholinergics
-Good oral care
-Avoid alc and drugs
-Take meds even if you feel fine