Psych Flashcards
Tx most effective against Negative sx
Atypical antipsychotics
Psychotic Disorders (5)
Delusional disorder Brief Psychotic disorder Schizophreniform disorder Schizophrenia Schizoaffective disorder
Delusional disorder
Poor insight
Psycho-social fx NOT markedly impaired
Non-bizarre delusions, plausible but false
Delusional disorder DSM5
Non bizarre delusions fr >1 month
Fx not impaired
Behavior not odd
Mood episodes (if present) are brief relative to delusion
Delusional disorder subtypes
Erotomanic- another person is in love with the pt
Grandiose- big head
Jealous
Persecutory- thinks someone is out to get them
Somatic- physical defect or medical condition
Mixed
Unspecified
Brief Psychotic Disorder
Sudden onset of at least 1 positive sx
lasting 1 day- 1 month, then return to normal
Emotional, labile, confused
Onset late 20s-early 30s
(may be w marked stress or post partum)
Brief Psychotic Disorder- worry about
High risk of Suicide
Brief Psychotic Disorder DSM5
Presence of 1 or more: delusions, hallucinations, disorg speech, grossly disorg/catatonic behavior
lasting 1 day-1 month, with eventual FULL RETURN TO NORMAL fx
Schizenophreniform Disorder
Essential features same as Schizophrenia, but
SHORTER DURATION
1-6 months
1/3 recover
2/3 progress to Schizophrenia
Schizophreniform disorder DSM5
Presence of TWO or more: Delusions, hallucinations, disorg speech, grossly disorg/catatonic behavior
lasting 1 month-6 months
Schizophrenia
Heritability 70-90%
1st deg relative risk is 10x that of other population
Males have earlier age of onset 18-25 YO
females: 25-35 YO
Schizophrenia
Neg sx often appear first
Decreased life expectancy- Men 15 years, women 12 years earlier
d/t ischemic heart dz, and CA
Schizophrenia DSM5
at least 1 month of 2+ of the following: delusions, hallucinations, disorg speech, disorg/catatonic behavior, negative sx
Social/job dysfunction
lasting 6 MONTHS
Prognosis with Schizophrenia is BETTER if:
female, later onset
acute onset w precip factor
brief duration, early intervention, tx compliance
positive sx
mood disturbance, family hx of mood disorder
high SES, married, good support system
Good pre-morbid functioning
Schizoaffective disorder
Schizophrenia
PLUS
A mood disorder
Schizoaffective disorder subtypes
Bipolar or Depressed
Delusions/hallucinations 2 wks and normal mood
more common in women (esp depressed)
Schizoaffective prognosis is
better than Schizoaphrenia
Schizoaffective Disorder DSM5
Meet criteria for Schizophrenia and ALSO has Major depressive, Manic, or Mixed episode
must have 2+ wks of delusions/hallucinations without prominent mood
mood sx present for sig portion of illness
Tx for Psychotic disorders
Start antipsych at low dose
Avoid use of 2 antipsychotics
When do things start to improve?
Hallucinations over days
Negative sx, delusions, cognitive def take much longer IF they improve
Indications for hospitalization
DTS
DTO
Command hallucinations
Unable to care for self
1st gen, conventional tx
Dopamine blockers (D2 receptor blockade)
used inpatient; IV
Chlorpromazine (Thorazine)
Haloperidol (Haldol)
Atypical Antipsychotics (2nd gen)
used outpatient
Aripiprazole (Abilify) Clozapine (Clozaril) Olanzapine (Zyprexa) Quetiapine (Seroquel) Risperidone (Risperdal)
SE of Clozapine (Clozaril)
Agranulocytosis
regular CBC and WBC monitoring (weekly initially)
SE of Olanzapine (Zyprexa)
Zyprexa DM
Weight gain
SE of Risperidone (Risperdal)
Prolactin, EPS
All Atypical Antipsych have a BLACK BOX WARNING for
Elderly
EPS- Extrapyramidal sx
Acute dystonic rxn Parkinsonism Akathisia Tardive dyskinesia NMS (lead pipe rigid)
Palliative care
relieving pain without dealing with underlying cause
-not trying to treat the medical condition
Palliative care is for those expected to pass away in
the next few years
5 emotional stages of dying
Denial-isolation Anger Bargaining Depression Acceptance
Hospice care
when it goes from Serious illness –> Terminal condition
Hospice
More intense focus on alleviating fear, anxiety, physical sx, emotional/spiritual distress
Life expectancy over the last 40 years has increased from
68—> 78
MDs overestimate life exp by
3x-5x d/t
difficulty imparting bad news
avoid dashing Hope
Seniors list these as top desires when living with chronic illness
Maintain independence
Be free of pain
Not be burden to family