Psych Flashcards

1
Q

How do you manage neuroleptic malignant syndrome?

A

Stop antipsychotic
Bromocriptine

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2
Q

What is the classic quadrate of post-traumatic stress disorder?

A

Reliving the situation
Avoidance
Hyperarousal
Emotional numbing
(prescent for > 1month)

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3
Q

How do you treat PTSD?

A

Trauma-focused CBT and/or Eye movement desensitization and reprocessing (in severe cases)
SSRI’s (2nd line)

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4
Q

What are Schneider’s first rank symptoms of schizophrenia?

A

Thought disorders
Delusional perceptions
Passivity
3rd person auditory hallucinations

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5
Q

What are the two pathways in the brain that relate to the symptoms of schizophrenia?

A

Mesolimbic - ↑dopamine causes positive symptoms
Mesocortical - ↓dopamine causes negative, cognitive and affective symptoms

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6
Q

What are the two pathways in the brain that relate to the side effects of antipsychotics?

A

Nigrostriatal - ↓ dopamine causes EPS & tardive dyskinesia
Tuberinfundibulum - ↓ dopamine causes hyperprolactinaemia

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7
Q

What are three examples of atypical (second-generation) antipsychotics?

A

Clozapine
Risperidone
Olanzapine

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8
Q

What are two examples of typical (first-generation) antipsychotics?

A

Haloperidol
Chlopromazine

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9
Q

How should lithium be monitored?

A

Sample should be taken 12 hours post-dose
After starting lithium levels should be checked weekly & after dose changes
Then when stable 3 monthly
TFT & U&E 6 monthly

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10
Q

What are some possible causes of lithium toxicity?

A

dehydration
renal failure
drugs: diuretics, ACE inhibitors/angiotensin II receptor blockers, NSAIDs & metronidazole.

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11
Q

Above what level is considered lithium toxicity?

A

Lithium toxicity = concentrations > 1.5 mmol/L.

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12
Q

What are the symptoms of lithium toxicity?

A

coarse tremor (a fine tremor is seen in therapeutic levels)
hyperreflexia
acute confusion
polyuria
seizure
coma

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13
Q

What are some of the common side-effects of lithium?

A

fine tremor
nephrotoxicity
hypothyroidism or hyperparathyroidism
weight gain & IIH

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14
Q

What are the medication options for mood stabilisers in bipolar disorder?

A

1st line is Lithium
2nd line is Sodium Valproate, Olanzapine or Quetiapine

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15
Q

What are the differences between grief and pathological grief?

A

Pathological < 12 months
Wants to die not just to be with loved one
Functional impairment

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16
Q

What questionnaire can be used in eating disorders?

A

SCOFF questionnaire

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17
Q

What are the features of neuroleptic malignant syndrome?

A

pyrexia
muscle rigidity
autonomic lability (hypertension, tachycardia & tachypnoea)
agitated delirium with confusion

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18
Q

What is neuroleptic malignant syndrome?

A

Condition seen in patients taking antipsychotic medication. It occurs within hours to days of starting an antipsychotic

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19
Q

What are the features of serotonin syndrome?

A

hyperreflexia
myoclonus
rigidity
autonomic excitation - (sweating & hyperthermia)
confusion

20
Q

What are the common causes of serotonin syndrome?

A

monoamine oxidase inhibitors
SSRIs
(if St John’s Wort or tramadol is taken in addition to SSRI’s it may cause it)
ecstasy
amphetamines

21
Q

How do you manage serotonin syndrome?

A

Supportive including IV fluids
Benzodiazepines
More severe cases - serotonin antagonists such as cyproheptadine & chlorpromazine

22
Q

What are the common side effects of tricyclic antidepressants?

A

drowsiness
dry mouth
blurred vision
constipation
urinary retention

23
Q

How do you treat acute stress disorder?

A

trauma-focused cognitive-behavioural therapy (CBT) is usually used first-line
benzodiazepines

24
Q

What is acute stress disorder?

A

Acute stress reaction that occurs in the first 4 weeks after a person has been exposed to a traumatic event

25
Q

How do you manage alcohol detox?

A

Long acting benzodiazepine - Chlordiazepoxide

26
Q

How do you treat delirium tremens?

A

IV Pabrinex and high dose Benzodiazepine.

27
Q

What blood test results would you expect to find in neuroleptic malignant syndrome?

A

↑ CK (creatine kinase)
↑ white cell count
Deranged LFT’s
Acute renal failure → abnormal U&E’s
Metabolic acidosis

28
Q

What are the features of schizoid personality disorder?

A

Indifference to praise and criticism
Preference for solitary activities
Lack of interest in sexual interactions

29
Q

What are the features of schizotypal personality disorder?

A

Odd beliefs and magical thinking
Odd, eccentric behaviour
Ideas of reference

30
Q

What are the features of histrionic personality disorder?

A

Promiscuous
Centre of attention
Shallow & emotional

31
Q

What are the features of borderline personality disorder?

A

Unstable relationships
Impulsive, self-harms, attention-seeking behaviour

32
Q

What electrolyte imbalances present in refeeding syndrome?

A

Hypomagnesaemia, hypokalaemia and hypophosphataemia

33
Q

What is used to treat ADHD and what contraindications are there?

A

Methylphenidate
> 5yrs
Cardiotoxic

34
Q

What are there features of anorexia nervosa?

A

High cortisol, amenorrhea, lanugo hair, low T3 levels

35
Q

What do PHQ scores indicate?

A

5-9 mild, 10-14 moderate, 15-19 moderately severe, 20-27 severe

36
Q

What is the difference between mania and hypomania?

A

Mania - prolonged time course (longer than 7-10 days) and the presence of psychotic symptoms

37
Q

What is section 136 used for?

A

Someone found in a public place with a mental disorder can be taken by the police to a Place of Safety

38
Q

Which SSRI should be used for children under 18?

A

Fluoxetine

39
Q

How should you manage acute dystonia secondary to antipsychotics?

A

procyclidine

40
Q

Which antipsychotic had the best side-effect profile?

A

Aripiprazole

41
Q

How do you treat borderline personality disorder?

A

Dialectical behavioural therapy

42
Q

What is the difference between PTSD and Acute stress disorder?

A

Acute stress disorder = occurs in the 4 weeks after a traumatic event
PTSD = diagnosed after 4 weeks

43
Q

How do you manage mania/hypomania?

A
  1. stop antidepressant if the patient takes one
  2. antipsychotic therapy e.g. olanzapine or haloperidol
44
Q

What are two examples of SNRIs?

A

venlafaxine and duloxetine

45
Q

What medication can be used to treat Akathisia (restlessness)?

A

Propanolol

46
Q

What medication can be used to treat tardive dyskinesia?

A

Tetrabenazine

47
Q

What is Orthello

A