Paeds Flashcards
How do you manage croup?
Single dose dexamethasone
How do you manage croup if severe?
Oxygen and nebulised adrenaline
How do you manage asthma in those under 5?
- SABA
- Low does corticosteroids
- Leukotriene antagonist (Montelukast)
- Refer
How do you manage asthma in those 5-12 years?
- SABA
- Low dose corticosteroids
- LABA (salmeterol)
- Increase corticosteroid & consider montelukast or theophylline
- High dose corticosteroid
How do you manage asthma in those over 12 years?
- SABA
- Low dose corticosteroids
- LABA (salmeterol)
- Increase corticosteroid & consider montelukast or theophylline or LAMA (tiotropium)\
- High dose corticosteroid
What are the indications of a life-threatening asthma attack?
Peak flow < 33% predicted, hypotension, exhaustion and poor respiratory effort, cyanosis, altered consciousness or silent chest
What are the indications of a severe asthma attack?
Peak flow < 50% predicted, sats <92%, respiratory distress, unable to complete sentences in one breath,RR >40 in 1-5 yrs or >30 >5yrs, HR >140 in 1-5 yrs or > 125 in > 5 yrs.
What are the steps in the acute management of a severe asthma attack?
- Nebulised salbutamol (&ipratropium bromide)
- Oral prednisone
- IV hydrocortisone
- IV magnesium sulphate
- IV salbutamol
- IV aminophylline
What is the investigation of choice for intussusception?
Abdominal US
What causes hand, foot and mouth?
Coxsackie A16
What are the features of hand, foot and mouth?
Mild systemic upset (sore throat and fever), oral ulcers followed by vesicles on the palms and soles
What are the signs of vitamin D deficiency in children?
Poor growth, delayed teeth, swollen wrists and frontal bossing
What blood results are found in a child with rickets?
Low calcium, low phosphate, high ALP and high PTH
What is the treatment for bacterial meningitis in babies < 3 months?
IV cefotaxime and IV amoxicillin
What is the treatment for bacterial meningitis in children > 3 months?
IV cefotaxime (or ceftriaxone)
What are the features of Patau syndrome? - trisomy 13
Microcephaly, small eyes, cleft lip/palate, polydactyly, scalp lesion
What are the features of Edward’s syndrome? - trisomy 18
Micrognathia, Low-set ears, Rocker bottom feet, Overlapping of fingers
What are the features of Fragile X syndrome?
Learning difficulties, Macrocephaly, Long face, Large ears, Macro-orchidism
What are the features of Noonan syndrome?
Webbed neck, Pectus excavatum, Short stature, Pulmonary stenosis
What are the features of William’s syndrome?
Short stature, Learning difficulties, elfin facies, Friendly, extrovert personality, Transient neonatal hypercalcemia, supravalvular aortic stenosis
What congenital heart condition is associated with Down syndrome?
Atrioventricular septal defect
What congenital heart conditions are most commonly associated with Down syndrome?
Endocardial cushion defect (AVSD)
Ventricular septal defect
What are the features of Down syndrome?
Hypotonia, Brachycephaly, Short neck, Short stature, Flattened face and nose, Prominent epicanthic folds, Single palmar crease, learning disability
What are the features on the combined test that indicate Down syndrome?
Nuchal translucency >6mm, increased beta-HCG and low PAPPA
What are the red high-risk signs in a sick child?
Mottled/ashen/blue skin, reduced skin turgor, grunting, tachypnoea >60, moderate recessions, non-blanching rash, bulging fontanelle, age <3 months & temp 38℃
What is a venous hum?
Is a benign murmur heard in children and sounds like a continuous blowing noise heard below the clavicles
What are the features of measles?
Prodromal phase: Fever, conjunctivitis, irritable
Koplik spots
Rash - maculopapular rash starts behind ear then whole body
What is the most common complication of measles?
Otitis media
What are the features of chickenpox?
Fever initially
Itchy rash starting on head/trunk - initially maculopapular then vesicular
Mild systemic upset
What are the features of mumps?
Fever, malaise, muscular pain
Parotitis (‘earache’, ‘pain on eating’): unilateral initially then becomes bilateral
What are the features of rubella?
Rash: pink maculopapular, initially on face before spreading to whole body, usually fades by the 3-5 day
Lymphadenopathy: suboccipital and postauricular
What causes erythema infectiosum?
Parvovirus B19
What are the features of erythema infectiosum?
Also known as fifth disease or ‘slapped-cheek syndrome’
Lethargy, fever, headache
‘Slapped-cheek’ rash spreading to proximal arms and extensor surfaces
What are the features of scarlet fever?
Fever, malaise, tonsillitis
‘Strawberry’ tongue
Sandpaper rash - fine punctate erythema sparing the area around the mouth (circumoral pallor)
What causes scarlet fever?
Reaction to erythrogenic toxins produced by Group A haemolytic streptococci
How do you treat scarlet fever?
Phenoxymethylpenicillin (penicillin V) for 10 days
What causes roseola infantum?
Human Herpes virus 6 (also known as sixth disease)
What are the features of roseola infantum?
High-grade fever which resolves before onset of rash. Febrile seizures. Starts on the trunk before spreading to the limbs, maculopapular rash and not itchy.
What causes whooping cough?
Pertussis bordetella
How do you test for whooping cough?
Nasal swab for Pertussis bordetella
When should whooping cough be considered?
Acute cough >2 weeks and has one or more of the following features:
Paroxysmal cough.
Inspiratory whoop.
Post-tussive vomiting.
Undiagnosed apnoeic attacks in young infants.
How should whooping cough be managed?
Notifiable disease
School exclusion: 48 hours after commencing antibiotics
Oral macrolide (e.g. clarithromycin or azithromycin)
Household contacts antibiotic prophylaxis
Infants < 6months admitted
What are the notifiable diseases?
Scarlet fever, Rubella, Measles
What are the features of Necrotising enterocolitis?
Vomiting, diarrhoea, feeding intolerance, abdominal distension, hematochezia and abdominal discolourartion
What investigations should be used for Necrotising enterocolitis and what will they show?
Abdominal x-ray - dilated bowel loops, bowel wall oedema, pneumatosis intestinalis, portal vein gas, pneumoperitoneum, Rigler sign (air in & out of bowel)
What are the four features that makeup Tetralogy of Fallot?
- Ventricular septal defect
- Right ventricular hypertrophy
- Pulmonary stenosis
- Overriding aorta
What is the clinical presentation of Tetralogy of Fallot?
Tet spells (cyanotic, tachypnoea, loss of consciousness in first month of life), ejection systolic murmur at left sternal edge, boot-shaped heart on x-ray, low birth weight and poor feeding
What are the clinical features of Transposition of the great arteries?
cyanosis, tachypnoea, loud single S2, prominent right ventricular impulse on palpation, ‘egg-on-side’ appearance on chest x-ray
What is Ebstein’s anomaly?
Low insertion of the tricuspid valve resulting in a large atrium and small ventricle
What are the feature of coarctation of the aorta?
Radio-femoral delay
Mid systolic murmur, maximal over back
Heart failure
What are the features of Ebstein’s anomaly?
Cyanosis, hepatomegaly, tricuspid regurgitation
Prominent ‘a’ wave in the distended jugular venous pulse
Pansystolic murmur, worse on inspiration
Right bundle branch block → widely split S1 and S2
What causes Ebstein’s anomaly and what other heart condition is associated with Ebstein’s?
Exposure to lithium in-utero
Patent foramen ovale (PFO) or atrial septal defect (ASD) and WPW
What murmur is associated with an atrial septal defect?
Ejection systolic murmur, fixed splitting of S2
What murmur is associated with a ventricular septal defect?
Pan-systolic murmur
How do you treat a patent ductus arteriosus?
Indomethacin or ibuprofen (inhibits prostaglandin synthesis)
What are the features associated with PDA?
Left subclavicular thrill, continuous ‘machinery’ murmur
Large volume, bounding, collapsing pulse
Wide pulse pressure and heaving apex beat
Why should aspirin not be given to children?
Reye syndrome
What are the components of the APGAR score?
Pulse, respiratory effort, colour, muscle tone and reflex irritability.
If a newborn has an abnormal hearing screen, what should be done next?
Auditory brainstem response test
What is the most common cause of congenital adrenal hyperplasia?
21-hydroxylase deficiency
What result does congenital adrenal hyperplasia have on hormone levels?
Low cortisol and aldosterone
High ACTH and high testosterone
How might congenital adrenal hyperplasia present?
Severe - Ambiguous genitalia, salt wasting (vomiting, dehydration and hypotension), hyponatraemia, hyperkalaemia and hypoglycaemia.
Mild - early puberty
What is Reye syndrome and what causes it?
Linked to aspirin use and is characterised by encephalopathy and liver damage
What are the two most common causes of nephritis in children?
IgA nephropathy and post-streptococcal glomerulonephritis
What are the differences between IgA nephropathy and post-streptococcal glomerulonephritis?
post-streptococcal nephritis associated with low complement levels
main symptom in post-streptococcal glomerulonephritis is proteinuria (although haematuria can occur)
there is typically an interval between URTI & onset of renal problems in post-streptococcal nephritis
What are the 4 features of Henoch-Schonlein purpura?
- Purpura (palpable)
- Arthritis/arthralgia (knees and ankles)
- IgA nephritis (haematuria &/or proteinuria)
- GI involvement (abdo pain)
What causes Henoch-Schonlein purpura?
Often triggered URTI (IgA vasculitis)
What is the cause of post-streptococcal glomerulonephritis?
Occurs 1 – 3 weeks post-β-haemolytic streptococcus infection eg. tonsillitis or impetigo
What are the features of post-streptococcal glomerulonephritis?
Haematuria, oligouria, cola coloured urine, peripheral or periorbital oedema