GP Flashcards
What can be used in an opioid overdose?
Naloxone
What drugs can be used to aid alcohol abstinence?
disulfram - severe reaction to alcohol
acamprosate - reduces craving
What can be used in an opioid overdose?
Naloxone
What can be used in a paracetamol overdose?
Activated charcoal if ingested < 1 hour ago
N-acetylcysteine (NAC)
What is the classic triad of diabetic ketoacidosis?
- Acidaemia (metabolic acidosis & hyperkalaemia)
- Hyperglycaemia
- Ketonaemia
What can be used to reverse the action of LMWH and unfractionated heparin?
Protamine
What deficiency causes haemophilia A?
factor VIII
What deficiency causes haemophilia B?
Factor IX
What will show on the blood tests in haemophilia?
prolonged APTT
bleeding time, thrombin time, prothrombin time normal
What can be used in the long-term management of sickle-cell anaemia to prevent a crisis?
Hydroxyurea
increases the HbF levels
What is used to diagnose sickle cell anaemia?
haemoglobin electrophoresis
What is the cause of sickle cell anaemia?
Autosomal recessive condition HbSS
Sickle cell trait = carrier (HbAS)
What is the stepwise management for COPD in patients that are steroid responsive (asthmatic features/atopic illness/variation in FEV1)?
Step 1: SABA or SAMA
Step 2: SABA + LABA + ICS
Step3: SABA+LABA+ICS+LAMA
What is the stepwise management for COPD in patients that are NOT steroid responsive?
Step 1: SABA or SAMA
Step 2: SABA + LABA + LAMA
How do you treat a peptic ulcer?
Lifestyle modifications + lansoprazole + clarithromycin + metronidazole