Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PT III - DEENT > Psoriasis and Rosacea Seborrhea (Bellanger) > Flashcards

Psoriasis and Rosacea Seborrhea (Bellanger) Flashcards

1
Q

A skin disease that affects the middle third of the face, causing persistent redness over the areas of the face and nose. There is no confirmatory lab test and no cure.

A

rosacea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Rosacea usually occurs in those __ to __ years of age and is more common in ____. Etiology is unknown and the major pathogenic components are inflammatory, vascular and neural/hormonal.

A

30; 50; women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The clinical presentation of subtype 1 rosacea

A

erythematotelangiectatic:
persistent erythema of central face
easily irritated facial skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The clinical presentation of subtype 2 rosacea

A

papulopustular:
subtype 1 +
dome-shaped erythematous papules and some pustules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The clinical presentation of subtype 3 rosacea

A

phymatous (Rhinophyma):
thickened skin with prominent pores
+/- subtype 1 & 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The clinical presentation of subtype 4 rosacea

A 
ocular rosacea:
both eyes are usually affected
conjunctivitis
blepharitis
styes
keratitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Rosacea aggravating factors:

  • ____ sun exposures
  • stress/anxiety
  • humidity/extremes of weather/wind
  • exercise
  • ____ beverages
  • smoking
  • ____ and ____ foods
  • medications (?)
A
  • prolonged
  • alcoholic
  • hot; spicy
  • eg., vasodilative drugs, calcium channel blockers, opiates
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rosacea non-pharmacologic basic skin care:

  • avoid potentially exacerbating factors
  • gently ____ free skin cleanser (avoid ____, ____ and ____ cosmetics)
  • moisturizer
  • ____ daily (>SPF 15; broad spectrum
A
  • soap; astringents, toners, waterproof

- photoprotection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ocular rosacea treatment:

  • ____ water soaks towel compress
  • ____ daily cleaning of base of lashes with baby shampoo or lid cleanser
  • artificial tear replacement
  • topical ____ gel
  • oral ____ or ____
  • refer severe cases to ophthalmologist
A
  • warm
  • twice
  • metronidazole
  • doxycycline; tetracycline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Rosacea topical agents (6)

A
  • metronidazole cream/gel
  • azelaic acid gel
  • brimonidine gel (reduces redness only)
  • benzoyl peroxide & clindamycin (papulopustular)
  • salfacetamide & sulfur (erythematotelangectatic)
  • topical retinoids (use with or without oral antibiotics in refractory rosacea)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Topical metronidazole

  • ____ line
  • ____ and ____ agent
  • inhibits growth of ____
  • side effects: burning, stinging, ____, ____
  • face should be clean before application
  • cosmetics may be used ___ minutes after application
A
  • first
  • anti-inflammatory; antimicrobial
  • Demodex brevis (mites)
  • dryness, itching
  • 5
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Azelaic acid 15% gel

  • ____ and ____ agent
  • for ____ to ____ papulopustular rosacea
  • face should be clean before application
  • cosmetics may be used after application
  • side effects: burning, stinging, itching, dryness, ____
  • reassess if it has not improved after 12 weeks
A
  • anti-inflammatory; antibacterial
  • mild; moderate
  • scaling
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Brimodine topical gel

A

alpha2 adrenergic agonist vasoconstricts, reducing redness in face

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

doxycycline (Oracea)

  • ____ dose
  • used only for ____ therapy for up to __ ___
A
  • anti-inflammatory

- systemic; 12 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antibiotic/anti-inflammatory oral agents:

  • doxycycline
  • tetracycline
  • minocycline
  • erythormycin
  • metronidazole
A
  • 50-100 mg/day for 6-12 weeks
  • 250-500 mg BID for 6-12 weeks
  • 50-100 mg BID for 6-12 weeks
  • 250-500 mg once or twice daily for 4-6 weeks
  • 200 mg once or twice daily for 4-6 weeks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Scaly dermatoses (3)

A

dandruff, seborrhea, psoriasis

17
Q

OTC ingredients for treatment of scaly dermatoses

A 
coal tar
ketoconazole
pyrithione zinc (rinse of vs. residual)
salycilic acid
selenium sulfide
sulfur
hydrocortisone
18
Q

A chronic, non-inflammatory hyperproliferative epidermal scalp condition (pruritus is common). Peak occurance is in adulthood with no gender preference.

A

dandruff

19
Q

Dandruff treatment goals:

  • reduce epidermal ____ rate of scalp skin
  • minimize the cosmetic embarrassement
  • minimize ____
A
  • turnover

- itching

20
Q

Dandruff general treatment approach

  • for mild presentation?
  • for moderate to severe presentation?
A
  • use non-medicated shampoo, wash hair daily or every other day; leave in for 3-5 minutes; rinse thoroughly
  • use OTC medicated shampoos; wash hair 2-3 times weekly for 2-3 weeks, then once weekly for control; leave in for 3-5 minutes; rinse thoroughly
21
Q

A chronic, inflammatory disorder occurring in areas of sebaceous gland activity; does not have a specific cure; neither harmful or contagious

A

seborrheic dermatitis

22
Q

Seborrheic dermatitis affected skin areas: (7)

A 
scalp
eyelids (blepharitis)
face
ears/ear canals
mid-upper chest and back
buttock crease/genital area
armpits
23
Q

Seborrhea triggers

A

HIV infection

Parkinsonism

24
Q

Seborrhea causes:

  • Malassezia (yeast) grows in the ____ along with bacteria
  • hormones
  • physical stress, fatigue, travel
  • ____ deficiency
  • obesity
  • change of season (worsens when ____)
A
  • sebum
  • zinc
  • cold
25
Q

Seborrhea physical characteristics:

  • ____ or dry scaling of scalp; “cradle cap”
  • mildly scaling eczematous patches on face at typical locations, often with itch and ____
  • itch and ____ of ear canal
  • blepharitis
  • well-demarcated eczematous patches on mid-upper ____
  • intertrigo (webs of fingers)
A
  • greasy
  • stinging
  • inflammation
  • trunk
26
Q

Seborrhea goals of treatment

A

-reduce inflammation and epidermal turnover rate and minimize/eliminate visible erythema and scaling

27
Q

Seborrhea general treatment approach/management strategies:

  • ____ or remove scales and crusts
  • inhibit ____ colonization
  • reduce erythema and itching
  • avoid ____, aftershave, ____, soaps
  • control secondary infections
A
  • loosen
  • yeast (Malassezia)
  • perfumes; ointments
28
Q

Seborrheic scales can be softened with a cream containing ____ acid and ____ or by ____/washing. Seborrheic skin should be ____ more often than usual.

A

salicylic; sulfur; wetting

washed

29
Q

To decrease fungal growth in seborrhea, wash the ____ with ____ shampoo (first line) or ____ ____shampoo (second line). May suggest topical cream treatments, such as ____ derivatives. Sometimes ____ light therapy.

A

ketoconazole; selenium sulfide
imidazole
ultraviolet

30
Q

Reduce seborrheic erythema and itching with corticosteroid ____ for the scalp, corticosteroid ____ for other parts of the body, and moisturizing ____ after washing. ____ shampoo and corticosteriod ____ must often be combined in therapy-resistant cases.

A

lotion; creams; emollients; ketoconazole; lotion

31
Q

Seborrheic treatment for infants:

  • remove scaling on scalp by massaging scalp with ____ ____, use a non-medicated shampoo (for severe cases, use ____ ____ 3-5% in olive oil or a water soluble base), use a soft bristle brush.
  • if they are over 2 y.o., use low potency ____
  • if on the face, wash with mild soap or cleanser, apply facial emollient - NO ____
A
  • baby oil; salicylic acid
  • hydrocortisone (0.5-1%)
  • steroids
32
Q

___ quantifies the extent and severity of skin involvement in different body regions as score. 0 means ___ ___, 72 means ___ ___

A

PASI (psoriasis area and severity index); no lesions; severe disease

33
Q

Psoriasis goals of treatment:

  • minimize/eliminate signs of psoriasis (____ and ____)
  • alleviate pruritus and minimize ____
  • reduce frequency of flare-ups
  • ensure appropriate treatment of associated conditions such as PsA, HTN, dyslipidemia, diabetes, clinical depression, or ____
  • avoid/minimize ____ ____ from topical or systemic treatments used
  • provide cost-effective therapy
  • provide guidance or counseling ____ ____
  • maintaining/improving ____ of ____
A
  • plaques; scales
  • excoriations
  • itching
  • adverse effects
  • as needed
  • quality; life
34
Q

Psoriasis lifestyle recommendations (5)

A
  • reduce stress
  • regular exercise
  • weight management
  • moderation of alcohol consumption
  • cessation of smoking
35
Q

Psoriasis non-pharmacologic treatments (3)

A
  • moisturizers/emollients
  • oatmeal baths
  • sunscreen
36
Q

Photochemotherapy:

  • PUVA (____+ ultraviolet A light)
  • MOA?
  • for patients with ____, ____ psoriasis
  • need skin ____ of lesion to confirm ____
  • ___% effective
A
  • psoralen
  • psoralen cross-links with DNA in presence of UVA light, effects immune response in skin and lymphocytes
  • severe; refractory
  • biopsy; diagnosis
  • 90
37
Q

Photochemotherapy

  • dosing?
  • side effects? (6)
A
  • 0.6-0.8 mg/kg PO Q2h before UVA exposure

- serious burns, increased risk of melanoma & non-melanoma skin CA, blistering, peeling, itching, nausea

PT III - DEENT (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions